公开(公告)号：US20170128029A1

公开(公告)日：2017-05-11

申请号：US15412885

申请日：2017-01-23

申请人： Scott Penfold ,  Mark R. Amato ,  Edward Ivanov ,  Jillian Reno ,  Nick Ruebel ,  Stephen Siedge ,  Lauri Reichert ,  Kyle Schmanke ,  W. Davis Lee ,  James P. Bennett

发明人： Scott Penfold ,  Mark R. Amato ,  Edward Ivanov ,  Jillian Reno ,  Nick Ruebel ,  Stephen Siedge ,  Lauri Reichert ,  Kyle Schmanke ,  W. Davis Lee ,  James P. Bennett

IPC分类号： A61B6/00 ,  G01T1/20 ,  G01N23/04 ,  A61B6/03 ,  A61N5/10

CPC分类号： A61B6/4417 ,  A61B6/032 ,  A61B6/037 ,  A61B6/4258 ,  A61B6/4266 ,  A61B6/50 ,  A61B6/5205 ,  A61B6/5235 ,  A61N5/1037 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/1069 ,  A61N5/107 ,  A61N5/1077 ,  A61N5/1081 ,  A61N5/1082 ,  A61N2005/1051 ,  A61N2005/1054 ,  A61N2005/1061 ,  A61N2005/1087 ,  A61N2005/1095 ,  A61N2005/1097 ,  G01N23/04 ,  G01N2223/1006 ,  G01T1/2018 ,  G21K1/08 ,  G21K5/04

摘要： The invention comprises an apparatus and method of use thereof for using a single patient position during, optionally simultaneous, X-ray imaging and positively charged particle imaging, where imaging a tumor of a patient using X-rays and positively charged particles comprises the steps of: (1) generating an X-ray image using the X-rays directed from an X-ray source, through the patient, and to an X-ray detector, (2) generating a positively charged particle image: (a) using the positively charged particles directed from an exit nozzle, through the patient, through the X-ray detector, and to a scintillator, the scintillator emitting photons when struck by the positively charged particles and (b) generating the positively charged particle image of the tumor using a photon detector configured to detect the emitted photons, where the X-ray detector maintains a position between said the nozzle and the scintillator during the step of generating a positively charged particle image.

公开(公告)号：US20170128747A1

公开(公告)日：2017-05-11

申请号：US15413066

申请日：2017-01-23

申请人： James P. Bennett ,  Kyle Schmanke ,  Lauri Reichert ,  Stephen Sledge ,  Nick Ruebel ,  Jillian Reno ,  Edward Ivanov ,  Mark R. Amato ,  Scott Penfold ,  W. Davis Lee

发明人： James P. Bennett ,  Kyle Schmanke ,  Lauri Reichert ,  Stephen Sledge ,  Nick Ruebel ,  Jillian Reno ,  Edward Ivanov ,  Mark R. Amato ,  Scott Penfold ,  W. Davis Lee

IPC分类号： A61N5/10 ,  A61B6/00

CPC分类号： A61N5/1049 ,  A61B6/032 ,  A61B6/4085 ,  A61B6/4258 ,  A61B6/5205 ,  A61B6/5235 ,  A61B6/582 ,  A61N5/1037 ,  A61N5/1067 ,  A61N5/1069 ,  A61N5/107 ,  A61N5/1077 ,  A61N5/1081 ,  A61N5/1082 ,  A61N2005/1051 ,  A61N2005/1054 ,  A61N2005/1061 ,  A61N2005/1087 ,  A61N2005/1095 ,  A61N2005/1097 ,  G21K1/08 ,  G21K5/04

摘要： The invention comprises an X-ray—positively charged particle double/dual exposure imaging apparatus and method of use thereof. Double exposure imaging of a tumor of a patient is performed using detector hardware responsive to both X-rays and positively charged particles. A near-simultaneous double exposure yields enhanced resolution due to the imaging rate versus patient movement, no requirement of a software overlay step of the X-ray based image and the positively charged particle based image, and enhancement of an X-ray image, the enhancement resultant from a differing physical interaction of the positively charged particles with the patient compared to interactions of X-rays and the patient. Further, resolution enhancements utilize individual particle tracking, as measured using detection screens, to determine a probable intra-patient path. Residual energy positively charged particles are optionally used to generate a second or dual image at a secondary detector, such as a detector detecting scintillation resultant from proton absorbance.

公开(公告)号：US20170036041A1

公开(公告)日：2017-02-09

申请号：US15334206

申请日：2016-10-25

申请人： Lauri Reichert ,  Stephen Sledge ,  Edward Ivanov ,  W. Davis Lee

发明人： Lauri Reichert ,  Stephen Sledge ,  Edward Ivanov ,  W. Davis Lee

IPC分类号： A61N5/10 ,  G21K5/04 ,  G21K1/093 ,  A61B6/03

CPC分类号： A61N5/1077 ,  A61B6/032 ,  A61B6/4092 ,  A61B6/4258 ,  A61B6/4266 ,  A61B6/485 ,  A61B6/487 ,  A61B6/5205 ,  A61N5/1037 ,  A61N5/1044 ,  A61N5/1067 ,  A61N5/1069 ,  A61N5/107 ,  A61N5/1082 ,  A61N2005/1054 ,  A61N2005/1074 ,  A61N2005/1087 ,  A61N2005/1095 ,  A61N2005/1097 ,  G21K1/08 ,  G21K1/093 ,  G21K5/04

摘要： The invention comprises a method and apparatus for directing charged particles into a patient from several directions. A delivery system is described that uses a primary beam line from an accelerator to a path switching magnet used to dynamically direct bunches of the positively charged particles down a selected pathway of a plurality of physically separated beam transport lines to a single patient treatment position, where the selected pathways enter the patient from two or more sides. Optionally, a repositionable treatment nozzle is repositioned to interface with each beam transport line, which allows the charged particle delivery system to use a single scanning capable nozzle in combination with delivery of the charged particles to the two or more sides of the patient to implement a tumor irradiation plan without a necessity of a moveable beamline in, at, or near a treatment room.

摘要翻译： 本发明包括一种用于将带电粒子从多个方向引导到患者体内的方法和装置。 描述了一种输送系统，其使用来自加速器的主波束线到路径切换磁体，用于将多个物理分离的波束输送线的选定路径的带正电荷的粒子的一束动态地引导到单个患者治疗位置， 选定的路径从两侧或两侧进入患者。 可选地，可重新定位的治疗喷嘴被重新定位以与每个束输送管线相接合，这允许带电粒子输送系统使用单一扫描能力的喷嘴与将带电粒子递送到患者的两侧或更多侧来实现 肿瘤照射计划，而不需要在治疗室内，附近或附近的可移动的束线。