Medical devices containing radiation resistant polymers
    1.
    发明申请
    Medical devices containing radiation resistant polymers 有权
    含抗辐射聚合物的医疗器械

    公开(公告)号:US20070020307A1

    公开(公告)日:2007-01-25

    申请号:US11184196

    申请日:2005-07-19

    IPC分类号: A61F2/02 C08G8/28

    CPC分类号: A61L31/10 C08L71/02 C08L63/04

    摘要: The present invention relates generally to radiation-resistant medical devices which contain polymer regions for release of therapeutic agents. The present invention also relates to radiation-resistant copolymer materials for use in connection with insertable or implantable medical devices. The radiation-sterilized medical device comprises (a) a release region and (b) at least one therapeutic agent and the release region comprises a phenoxy resin block.

    摘要翻译: 本发明一般涉及含有用于释放治疗剂的聚合物区域的耐辐射医疗装置。 本发明还涉及用于与可插入或可植入的医疗装置相结合的耐辐射共聚物材料。 辐射消毒的医疗装置包括(a)释放区和(b)至少一种治疗剂,并且释放区包含苯氧树脂嵌段。

    Medical devices containing radiation resistant polymers
    3.
    发明授权
    Medical devices containing radiation resistant polymers 有权
    含抗辐射聚合物的医疗器械

    公开(公告)号:US08722074B2

    公开(公告)日:2014-05-13

    申请号:US11184196

    申请日:2005-07-19

    IPC分类号: A61F2/02

    CPC分类号: A61L31/10 C08L71/02 C08L63/04

    摘要: The present invention relates generally to radiation-resistant medical devices which contain polymer regions for release of therapeutic agents. The present invention also relates to radiation-resistant copolymer materials for use in connection with insertable or implantable medical devices. The radiation-sterilized medical device comprises (a) a release region and (b) at least one therapeutic agent and the release region comprises a phenoxy resin block.

    摘要翻译: 本发明一般涉及含有用于释放治疗剂的聚合物区域的耐辐射医疗装置。 本发明还涉及用于与可插入或可植入的医疗装置相结合的耐辐射共聚物材料。 辐射消毒的医疗装置包括(a)释放区和(b)至少一种治疗剂,并且释放区包含苯氧树脂嵌段。

    Implantable or insertable medical devices visible under magnetic resonance imaging
    5.
    发明申请
    Implantable or insertable medical devices visible under magnetic resonance imaging 有权
    可植入或可插入的医疗器械在磁共振成像下可见

    公开(公告)号:US20070167735A1

    公开(公告)日:2007-07-19

    申请号:US11637263

    申请日:2006-12-12

    IPC分类号: A61B5/05

    摘要: Disclosed is an implantable or insertable medical device comprising (a) a substrate and (b) a hydrogel polymer coating at a least a portion of the surface of the substrate, wherein the hydrogel polymer is adapted to render the medical device visible under magnetic resonance imaging (MRI) upon insertion or implantation of the medical device into a patient. Also disclosed is the use of such a hydrogel coated implantable or insertable medical device in a medical procedure, wherein during or after insertion or implantation of the medical device in a patient, the position of the medical device is viewed under MRI. The use of a hydrogel polymer for coating a medical device wherein the hydrogel polymer is adapted to render a medical device coated with the hydrogel polymer visible under MRI and a hydrogel polymer adapted to render a medical device coated therewith visible under MRI are also disclosed.

    摘要翻译: 公开了一种可植入或可插入的医疗装置,其包括(a)基底和(b)在所述基底表面的至少一部分表面上的水凝胶聚合物涂层,其中所述水凝胶聚合物适于使所述医疗装置在磁共振成像 (MRI)在将医疗装置插入或植入患者体内时。 还公开了在医疗过程中使用这种水凝胶涂覆的可植入或可插入的医疗装置,其中在将医疗装置插入或植入患者体内或之后,在MRI下观察医疗装置的位置。 还公开了使用水凝胶聚合物涂覆医疗装置,其中水凝胶聚合物适于使涂覆有水凝胶聚合物的医疗装置在MRI下可见,并且还公开了适于使其涂覆的医疗装置在MRI下可见的水凝胶聚合物。

    Implantable or insertable medical devices visible under magnetic resonance imaging
    6.
    发明授权
    Implantable or insertable medical devices visible under magnetic resonance imaging 有权
    可植入或可插入的医疗器械在磁共振成像下可见

    公开(公告)号:US08163326B2

    公开(公告)日:2012-04-24

    申请号:US11637263

    申请日:2006-12-12

    IPC分类号: B05D3/02 B05D3/06 A61B5/05

    摘要: Disclosed is an implantable or insertable medical device comprising (a) a substrate and (b) a hydrogel polymer coating at a least a portion of the surface of the substrate, wherein the hydrogel polymer is adapted to render the medical device visible under magnetic resonance imaging (MRI) upon insertion or implantation of the medical device into a patient. Also disclosed is the use of such a hydrogel coated implantable or insertable medical device in a medical procedure, wherein during or after insertion or implantation of the medical device in a patient, the position of the medical device is viewed under MRI. The use of a hydrogel polymer for coating a medical device wherein the hydrogel polymer is adapted to render a medical device coated with the hydrogel polymer visible under MRI and a hydrogel polymer adapted to render a medical device coated therewith visible under MRI are also disclosed.

    摘要翻译: 公开了一种可植入或可插入的医疗装置,其包括(a)基底和(b)在所述基底表面的至少一部分表面上的水凝胶聚合物涂层,其中所述水凝胶聚合物适于使所述医疗装置在磁共振成像 (MRI)在将医疗装置插入或植入患者体内时。 还公开了在医疗过程中使用这种水凝胶涂覆的可植入或可插入的医疗装置,其中在将医疗装置插入或植入患者体内或之后,在MRI下观察医疗装置的位置。 还公开了使用水凝胶聚合物涂覆医疗装置,其中水凝胶聚合物适于使涂覆有水凝胶聚合物的医疗装置在MRI下可见,并且还公开了适于使其涂覆的医疗装置在MRI下可见的水凝胶聚合物。

    Injectable therapeutic formulations
    7.
    发明申请
    Injectable therapeutic formulations 审中-公开
    可注射的治疗剂型

    公开(公告)号:US20050064045A1

    公开(公告)日:2005-03-24

    申请号:US10667151

    申请日:2003-09-18

    摘要: Sterile injectable formulations, which comprise the following: (a) a ablation agent in an amount effective to cause necrosis of tissue, and (b) a biodisintegrable viscosity adjusting agent in an amount effective to render the formulation highly viscous, (c) an optional imaging contrast agent, (d) an optional therapeutic agent, and (e) an optional liquid selected from water and an organic solvent. Also described are novel prostatic ablation formulations, which comprise a prostatic ablation agent selected from free-radical generating ablation agents, oxidizing ablation agents and tissue fixing ablation agents. Further aspects of the invention relate to methods of treating a variety of diseases and conditions, including benign prostatic hypertrophy, in which above injectable formulations are injected into the tissue of a subject, optionally with the assistance of a non-invasive imaging technique.

    摘要翻译: 无菌可注射制剂,其包含以下物质:(a)有效引起组织坏死的量的消融剂,和(b)有效使制剂高度粘稠的量的生物可分解粘度调节剂,(c)任选的 成像造影剂,(d)任选的治疗剂,和(e)选自水和有机溶剂的任选液体。 还描述了新型前列腺消融制剂,其包含选自自由基产生消融剂,氧化消融剂和组织固定消融剂的前列腺消融剂。 本发明的其它方面涉及治疗各种疾病和病症(包括良性前列腺肥大)的方法,其中任选地在非侵入性成像技术的帮助下,上述可注射制剂注射到受试者的组织中。