Devices and methods for treatment of heart failure and associated conditions

    公开(公告)号:US08265760B2

    公开(公告)日:2012-09-11

    申请号:US12485895

    申请日:2009-06-16

    Abstract: Devices and methods of use identification, treatment, and/or management of heart failure and/or associated conditions. Methods may include providing a baroreflex therapy system, providing an implantable measurement device proximate a blood vessel of a patient, the implantable measurement device including a plurality of electrodes, determining an impedance of the blood vessel with the implantable measurement device over a time period of at least one cardiac cycle, generating at least one signal representative of a pressure waveform based on the impedance, activating, deactivating or otherwise modulating the baroreflex therapy system to deliver a therapy to treat heart failure based at least in part on the at least one signal representative of the pressure waveform.

    Devices and methods for treatment of heart failure and associated conditions
    3.
    发明授权
    Devices and methods for treatment of heart failure and associated conditions 有权
    用于治疗心力衰竭和相关病症的装置和方法

    公开(公告)号:US08401652B2

    公开(公告)日:2013-03-19

    申请号:US13360339

    申请日:2012-01-27

    Abstract: Devices and methods of use are described for detecting and treating an undesirable level of fluid in a pulmonary circulation of a patient. An exemplary system may include an implantable baroreflex activation device including an electrode configured to be implanted proximate a baroreptor within a patient, an implantable sensor configured to provide an indication of a fluid level within the patient, and a control system coupled to the baroreflex activation device and the sensor. The control system may be programmed to automatically detect a level of a fluid in a pulmonary circulation of the patient with the sensor and upon detecting an undesirable level of the fluid in the pulmonary circulation, delivering a therapy via the electrode of the baroreflex activation device to reduce the level of fluid in the pulmonary circulation.

    Abstract translation: 描述了用于检测和治疗患者肺循环中不希望量的流体的装置和使用方法。 示例性系统可以包括可植入的压力反射激活装置,其包括构造成被植入在患者体内的压力调节器附近的电极,被配置为提供患者内的液位的指示的可植入传感器以及耦合到所述压力反射激活装置的控制系统 和传感器。 控制系统可以被编程为使用传感器自动检测患者的肺循环中的流体水平,并且在检测到肺循环中的不期望的液体水平时,通过压力反射激活装置的电极将治疗传递到 降低肺循环中的液体水平。

    Devices and methods for treatment of heart failure and associated conditions
    4.
    发明授权
    Devices and methods for treatment of heart failure and associated conditions 有权
    用于治疗心力衰竭和相关病症的装置和方法

    公开(公告)号:US08326430B2

    公开(公告)日:2012-12-04

    申请号:US12485895

    申请日:2009-06-16

    Abstract: Devices and methods of use identification, treatment, and/or management of heart failure and/or associated conditions. Methods may include providing a baroreflex therapy system, providing an implantable measurement device proximate a blood vessel of a patient, the implantable measurement device including a plurality of electrodes, determining an impedance of the blood vessel with the implantable measurement device over a time period of at least one cardiac cycle, generating at least one signal representative of a pressure waveform based on the impedance, activating, deactivating or otherwise modulating the baroreflex therapy system to deliver a therapy to treat heart failure based at least in part on the at least one signal representative of the pressure waveform.

    Abstract translation: 用于识别,治疗和/或管理心力衰竭和/或相关病症的装置和方法。 方法可以包括提供压力反射治疗系统,提供靠近患者血管的可植入测量装置,所述可植入测量装置包括多个电极,所述可植入测量装置包括多个电极,所述可植入测量装置在一段时间内用所述可植入测量装置确定所述血管的阻抗 至少一个心动周期,基于所述阻抗产生代表压力波形的至少一个信号,激活,去激活或以其他方式调制所述压力反射治疗系统,以至少部分地基于所述至少一个信号代表递送治疗以治疗心力衰竭 的压力波形。

    DEVICES AND METHODS FOR TREATMENT OF HEART FAILURE AND ASSOCIATED CONDITIONS
    5.
    发明申请
    DEVICES AND METHODS FOR TREATMENT OF HEART FAILURE AND ASSOCIATED CONDITIONS 有权
    用于治疗心力衰竭和相关条件的装置和方法

    公开(公告)号:US20120123506A1

    公开(公告)日:2012-05-17

    申请号:US13360339

    申请日:2012-01-27

    Abstract: Devices and methods of use identification, treatment, and/or management of heart failure and/or associated conditions. Methods may include providing a baroreflex therapy system, providing an implantable measurement device proximate a blood vessel of a patient, the implantable measurement device including a plurality of electrodes, determining an impedance of the blood vessel with the implantable measurement device over a time period of at least one cardiac cycle, generating at least one signal representative of a pressure waveform based on the impedance, activating, deactivating or otherwise modulating the baroreflex therapy system to deliver a therapy to treat heart failure based at least in part on the at least one signal representative of the pressure waveform.

    Abstract translation: 用于识别,治疗和/或管理心力衰竭和/或相关病症的装置和方法。 方法可以包括提供压力反射治疗系统,提供靠近患者血管的可植入测量装置,所述可植入测量装置包括多个电极,所述可植入测量装置包括多个电极,所述可植入测量装置在一段时间内用所述可植入测量装置确定所述血管的阻抗 至少一个心动周期,基于所述阻抗产生代表压力波形的至少一个信号,激活,去激活或以其他方式调制所述压力反射治疗系统,以至少部分地基于所述至少一个信号代表递送治疗以治疗心力衰竭 的压力波形。

    DEVICES AND METHODS FOR TREATMENT OF HEART FAILURE AND ASSOCIATED CONDITIONS
    6.
    发明申请
    DEVICES AND METHODS FOR TREATMENT OF HEART FAILURE AND ASSOCIATED CONDITIONS 有权
    用于治疗心力衰竭和相关条件的装置和方法

    公开(公告)号:US20100004714A1

    公开(公告)日:2010-01-07

    申请号:US12485895

    申请日:2009-06-16

    Abstract: Devices and methods of use identification, treatment, and/or management of heart failure and/or associated conditions. Methods may include providing a baroreflex therapy system, providing an implantable measurement device proximate a blood vessel of a patient, the implantable measurement device including a plurality of electrodes, determining an impedance of the blood vessel with the implantable measurement device over a time period of at least one cardiac cycle, generating at least one signal representative of a pressure waveform based on the impedance, activating, deactivating or otherwise modulating the baroreflex therapy system to deliver a therapy to treat heart failure based at least in part on the at least one signal representative of the pressure waveform.

    Abstract translation: 用于识别,治疗和/或管理心力衰竭和/或相关病症的装置和方法。 方法可以包括提供压力反射治疗系统,提供靠近患者血管的可植入测量装置,所述可植入测量装置包括多个电极,所述可植入测量装置包括多个电极,所述可植入测量装置在一段时间内用所述可植入测量装置确定所述血管的阻抗 至少一个心动周期,基于所述阻抗产生代表压力波形的至少一个信号,激活,去激活或以其他方式调制所述压力反射治疗系统,以至少部分地基于所述至少一个信号代表递送治疗以治疗心力衰竭 的压力波形。

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