Medicine based on fenofibrate, and a method of preparing it
    3.
    发明授权
    Medicine based on fenofibrate, and a method of preparing it 失效
    基于非诺贝特的药物及其制备方法

    公开(公告)号:US4800079A

    公开(公告)日:1989-01-24

    申请号:US83409

    申请日:1987-08-10

    CPC分类号: A61K31/22 A61K9/5078

    摘要: A granular medicine based on fenofibrate, each granule comprising an inert core, a layer based on fenofibrate, and a protective layer, the medicine being characterized in that the fenofibrate in the layer based on fenofibrate is present in the form of crystalline microparticles of dimensions not greater than 30 microns, and preferably less than 10 microns.

    摘要翻译: 一种基于非诺贝特的颗粒药物,每个颗粒包含惰性核心,基于非诺贝特的层和保护层,该药物的特征在于,基于非诺贝特的层中的非诺贝特以不是的结晶微粒的形式存在 大于30微米,优选小于10微米。

    Method of preparing comtrolled release fenofibrate
    5.
    发明授权
    Method of preparing comtrolled release fenofibrate 失效
    制备松露非诺贝特的方法

    公开(公告)号:US4961890A

    公开(公告)日:1990-10-09

    申请号:US256836

    申请日:1988-10-12

    CPC分类号: A61K31/22 A61K9/5078

    摘要: A process for preparing a controlled release medicine containing fenofibrate in an intermediate layer in the form of cyrstalline microparticles included within pores of an inert matrix prepared by a process involving the sequential steps of dampening said inert core with a solution based on said biner, then projecting said fenofibrate microparticles in a single layer onto said dampened core, and thereafter drying before said solution based on said binder dissolves said fenofibrate microparticles and repeating said three steps in sequence until said intermediate layer is formed.