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    MEDICAL FLUID INJECTION AND INFLATION SYSTEM
    2.
    发明申请
    MEDICAL FLUID INJECTION AND INFLATION SYSTEM 有权
    医用流体注射和灌注系统

    公开(公告)号：US20070197963A1

    公开(公告)日：2007-08-23

    申请号：US11425497

    申请日：2006-06-21

    申请人： David Griffiths ,  Rosemary Almon-Martin ,  Alan Hirschman ,  David Reilly ,  Mark Trocki ,  Frederick Trombley ,  Arthur Uber ,  Thomas Weich ,  William Jaecklein

    发明人： David Griffiths ,  Rosemary Almon-Martin ,  Alan Hirschman ,  David Reilly ,  Mark Trocki ,  Frederick Trombley ,  Arthur Uber ,  Thomas Weich ,  William Jaecklein

    IPC分类号： A61M29/00

    CPC分类号： A61M25/10184 ,  A61M5/007 ,  A61M5/14566 ,  A61M5/16827 ,  A61M5/16854 ,  A61M25/007 ,  A61M25/104 ,  A61M2025/102 ,  A61M2025/1022

    摘要： A combined fluid injection and inflation system is disclosed and includes a fluid delivery system including at least one pressurizing device, a fluid path, and a control unit. The fluid path is adapted to connect the pressurizing device to a patient via a catheter including a balloon and inserted in the patient. The control unit is operable to control the fluid delivery system. In operation, the control unit selectively actuates the fluid delivery system to operate in a fluid injection mode or in a balloon inflation mode. In the fluid injection mode the pressurizing device delivers fluid to the fluid path for a fluid injection procedure. In the balloon inflation mode, the pressurizing device delivers fluid to the fluid path for inflating the balloon associated with the catheter. An operator control may be connected to the control unit for controlling the fluid delivery system and may be a handheld device.

    摘要翻译： 公开了组合的流体注入和充气系统，并且包括包括至少一个加压装置，流体路径和控制单元的流体输送系统。 流体路径适于经由包括球囊并且插入患者体内的导管将加压装置连接到患者。 控制单元可操作以控制流体输送系统。 在操作中，控制单元选择性地致动流体输送系统以流体注射模式或气球充气模式操作。 在流体注射模式中，加压装置将流体输送到流体路径用于流体注射程序。 在球囊膨胀模式中，加压装置将流体输送到流体路径，用于使与导管相关联的球囊膨胀。 操作员控制可以连接到控制单元以控制流体输送系统，并且可以是手持装置。

    DELIVERY OF AGENTS TO TISSUE
    3.
    发明申请
    DELIVERY OF AGENTS TO TISSUE 失效
    交付代理组织

    公开(公告)号：US20070106208A1

    公开(公告)日：2007-05-10

    申请号：US11460635

    申请日：2006-07-28

    申请人： Arthur Uber ,  Frederick Trombley ,  Eugene Gelblum ,  Edward Rhinehart ,  David Reilly ,  Page Cedarholm ,  Kevin Cowan ,  Mark Trocki ,  Alan Hirschman

    发明人： Arthur Uber ,  Frederick Trombley ,  Eugene Gelblum ,  Edward Rhinehart ,  David Reilly ,  Page Cedarholm ,  Kevin Cowan ,  Mark Trocki ,  Alan Hirschman

    IPC分类号： A61M31/00 ,  A01N1/02 ,  C12M1/12 ,  C12M1/24 ,  B65D25/04 ,  A01N1/00 ,  C12M3/00 ,  B65D1/24 ,  B65D1/36 ,  B65D57/00 ,  B65D85/00

    CPC分类号： A61J1/1443 ,  A61J1/1456 ,  A61J1/1475 ,  A61M5/142 ,  A61M5/1723 ,  A61M5/3145 ,  A61M31/005 ,  B01L3/502 ,  B01L2300/044 ,  B01L2300/0681 ,  G06F19/3468

    摘要： A system for injecting an injectate into patient includes a first pressurizable container for holding the injectate; a patient interface in fluid connection with the first pressurizable container, the patient interface being adapted to pass the injectate into tissue of the patient; a powered injector in operative connection with the first pressurizable container to pressurize the injectate; a controller system in operative connection with powered injector; and a stereotactic localization frame adapted to be placed in operative connection with the patient interface to assist in controlling localization of the patient interface. A system for processing cells (and/or other injectate components) includes a container and a plunger adapted to be slidably positioned within the container. The system includes at least one inlet port through which a fluid can enter the system and at least one effluent port through which an effluent can exit the system. The plunger section forms a sealing engagement with the inner wall of the container such that rearward motion of the plunger is adapted to draw fluid into the system via the inlet and forward motion of the plunger is adapted to force effluent out of the system via the effluent port.

    摘要翻译： 用于将注射器注射到患者体内的系统包括用于保持注射器的第一可加压容器; 与所述第一可加压容器流体连接的患者接口，所述患者接口适于将所述注射器通入患者的组织; 动力注射器，其与所述第一可加压容器可操作地连接以对所述注射器加压; 与动力注射器操作连接的控制器系统; 以及适于与病人界面操作连接的立体定向定位框架，以协助控制患者界面的定位。 用于处理细胞（和/或其它注射组分）的系统​​包括适于可滑动地定位在容器内的容器和柱塞。 该系统包括至少一个入口，流体可以通过该入口进入系统和至少一个流出物端口，流出物可通过该至少一个出口端口离开系统。 柱塞部分形成与容器的内壁的密封接合，使得柱塞的向后运动适于通过入口将流体引入系统，并且柱塞的向前运动适于通过流出物强制流出系统的流出物 港口。

    Container for agitating and injecting a multi-component medium
    4.
    发明申请
    Container for agitating and injecting a multi-component medium 有权
    用于搅拌和注射多组分介质的容器

    公开(公告)号：US20060184102A1

    公开(公告)日：2006-08-17

    申请号：US11394946

    申请日：2006-03-31

    申请人： Frederick Trombley ,  Arthur Uber ,  Edward Rhinehart ,  Rosemary Almon-Martin ,  Alan Hirschman

    发明人： Frederick Trombley ,  Arthur Uber ,  Edward Rhinehart ,  Rosemary Almon-Martin ,  Alan Hirschman

    IPC分类号： A61M37/00

    CPC分类号： A61M5/142 ,  A61M5/007 ,  A61M5/14546 ,  A61M5/14566 ,  A61M5/445 ,  A61M2205/3673 ,  B01F9/103 ,  B01F13/005

    摘要： A system for dispensing a medium includes at least a first container to hold the medium, a pressurizing device, such as a pump, in fluid connection with the container for pressurizing the medium, and an agitation mechanism or device to maintain the components of the medium in a mixed state. The container and the pressurizing device can be separate units, as in the case of an bag or bottle in fluid connection with a peristaltic or other type of pump. The container and the pump can also be combined in a single unit, as in the case of a syringe, wherein the syringe barrel of the syringe acts to contain the medium and the syringe plunger pressurizes the medium within the syringe barrel. A method of injecting a multi-component medium includes the step of agitating the medium (for example, as described above) before or during an injection procedure to maintain the components of the medium in a mixed state.

    摘要翻译： 用于分配介质的系统至少包括用于保持介质的第一容器，与容器流体连接的用于对介质加压的加压装置，例如泵，以及用于维持介质的组分的搅拌机构或装置 处于混合状态。 容器和加压装置可以是分离的单元，如在与蠕动或其它类型的泵流体连接的袋或瓶的情况下。 容器和泵也可以在单个单元中组合，如在注射器的情况下，其中注射器的注射器筒用于容纳介质，并且注射器柱塞对注射器筒内的介质加压。 注射多组分培养基的方法包括在注射过程之前或过程中搅拌培养基（例如，如上所述）以将培养基的组分维持在混合状态的步骤。

    FLUID DELIVERY SYSTEM, FLUID PATH, AND MEDICAL CONNECTOR FOR USE WITH THE FLUID DELIVERY SYSTEM AND FLUID PATH
    7.
    发明申请
    FLUID DELIVERY SYSTEM, FLUID PATH, AND MEDICAL CONNECTOR FOR USE WITH THE FLUID DELIVERY SYSTEM AND FLUID PATH 有权
    流体输送系统，流体路径和医疗连接器，用于流体输送系统和流体路径

    公开(公告)号：US20070129705A1

    公开(公告)日：2007-06-07

    申请号：US11426348

    申请日：2006-08-10

    申请人： Frederick Trombley ,  Kevin Cowan ,  Kraig McEwen ,  Joseph Havrilla

    发明人： Frederick Trombley ,  Kevin Cowan ,  Kraig McEwen ,  Joseph Havrilla

    IPC分类号： A61M25/00

    CPC分类号： A61M39/10 ,  A61M39/12 ,  A61M2039/1033 ,  A61M2039/1038

    摘要： A medical connector includes a body defining a lumen for fluid flow through the medical connector. The medical connector includes a luer member and an annular member disposed about the luer member. The annular member includes internal and/or external engagement structures. The medical connector may be provided on the outlet of a syringe or on a catheter. A fluid path is disclosed including a first section and a second section. The first and second sections may each include a medical connector to provide a removable connection with a syringe and a catheter, respectively. The medical connector may provide a removable connection between the first and second sections. A fluid delivery system is disclosed including an injector, a syringe operatively associated with the injector, and a fluid path connecting the syringe and a source of injection. The medical connector may provide a removable connection between the syringe and fluid path.

    摘要翻译： 医疗连接器包括限定用于通过医疗连接器的流体流动的内腔的主体。 医疗连接器包括鲁尔构件和围绕鲁尔构件设置的环形构件。 环形构件包括内部和/或外部接合结构。 医疗连接器可设置在注射器的出口或导管上。 公开了一种包括第一部分和第二部分的流体路径。 第一和第二部分可以各自包括医疗连接器，以分别提供与注射器和导管的可移除连接。 医疗连接器可以在第一和第二部分之间提供可移除的连接。 公开了一种流体递送系统，其包括注射器，与注射器可操作地相关联的注射器以及连接注射器和注射源的流体路径。 医疗连接器可以在注射器和流体路径之间提供可移除的连接。

    Method for agitating and injecting a multi-component medium
    8.
    发明申请
    Method for agitating and injecting a multi-component medium 审中-公开
    用于搅拌和注入多组分介质的方法

    公开(公告)号：US20060178628A1

    公开(公告)日：2006-08-10

    申请号：US11395552

    申请日：2006-03-31

    申请人： Frederick Trombley ,  Arthur Uber ,  Edward Rhinehart ,  Rosemary Almon-Martin ,  Alan Hirschman

    发明人： Frederick Trombley ,  Arthur Uber ,  Edward Rhinehart ,  Rosemary Almon-Martin ,  Alan Hirschman

    IPC分类号： A61M37/00

    CPC分类号： A61M5/142 ,  A61M5/007 ,  A61M5/14546 ,  A61M5/14566 ,  A61M5/445 ,  A61M2205/3673 ,  B01F9/103 ,  B01F13/005

    摘要： A system for dispensing a medium includes at least a first container to hold the medium, a pressurizing device, such as a pump, in fluid connection with the container for pressurizing the medium, and an agitation mechanism or device to maintain the components of the medium in a mixed state. The container and the pressurizing device can be separate units, as in the case of an bag or bottle in fluid connection with a peristaltic or other type of pump. The container and the pump can also be combined in a single unit, as in the case of a syringe, wherein the syringe barrel of the syringe acts to contain the medium and the syringe plunger pressurizes the medium within the syringe barrel. A method of injecting a multi-component medium includes the step of agitating the medium (for example, as described above) before or during an injection procedure to maintain the components of the medium in a mixed state.

    摘要翻译： 用于分配介质的系统至少包括用于保持介质的第一容器，与容器流体连接的用于对介质加压的加压装置，例如泵，以及用于维持介质的组分的搅拌机构或装置 处于混合状态。 容器和加压装置可以是分离的单元，如在与蠕动或其它类型的泵流体连接的袋或瓶的情况下。 容器和泵也可以在单个单元中组合，如在注射器的情况下，其中注射器的注射器筒用于容纳介质，并且注射器柱塞对注射器筒内的介质加压。 注射多组分培养基的方法包括在注射过程之前或过程中搅拌培养基（例如，如上所述）以将培养基的组分维持在混合状态的步骤。

    MEDICAL CONNECTOR, FLUID DELIVERY SYSTEM, AND METHOD OF USE THEREFOR
    9.
    发明申请
    MEDICAL CONNECTOR, FLUID DELIVERY SYSTEM, AND METHOD OF USE THEREFOR 审中-公开
    流体输送系统医疗连接器及其使用方法

    公开(公告)号：US20050015074A1

    公开(公告)日：2005-01-20

    申请号：US10604402

    申请日：2003-07-17

    申请人： Frederick Trombley

    发明人： Frederick Trombley

    IPC分类号： A61M25/00 ,  A61M25/16 ,  A61M25/18

    CPC分类号： A61M25/0014

    摘要： A medical connector device defines a first passage and a second passage, and includes a first connector and a second connector. The first connector is capable of connecting to a fluid container. The second connector is capable of connecting to a fluid conduit. The first passage extends into the fluid container, and allows air to be vented into the fluid container. The second passage extends between the first connector and the second connector, and allows for the transfer of fluid between the fluid container and the fluid conduit. The connector body may be incorporated into a fluid delivery system including a fluid container, such as a syringe, and a fluid conduit, such as a connector tubing.

    摘要翻译： 医疗连接器装置限定第一通道和第二通道，并且包括第一连接器和第二连接器。 第一连接器能够连接到流体容器。 第二连接器能够连接到流体导管。 第一通道延伸到流体容器中，并允许空气排放到流体容器中。 第二通道在第一连接器和第二连接器之间延伸，并允许在流体容器和流体导管之间传送流体。 连接器主体可以结合到包括诸如注射器的流体容器和诸如连接器管的流体导管的流体输送系统中。