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公开(公告)号：US20070197963A1
公开(公告)日：2007-08-23
申请号：US11425497
申请日：2006-06-21
申请人： David Griffiths , Rosemary Almon-Martin , Alan Hirschman , David Reilly , Mark Trocki , Frederick Trombley , Arthur Uber , Thomas Weich , William Jaecklein
发明人： David Griffiths , Rosemary Almon-Martin , Alan Hirschman , David Reilly , Mark Trocki , Frederick Trombley , Arthur Uber , Thomas Weich , William Jaecklein
IPC分类号： A61M29/00
CPC分类号： A61M25/10184 , A61M5/007 , A61M5/14566 , A61M5/16827 , A61M5/16854 , A61M25/007 , A61M25/104 , A61M2025/102 , A61M2025/1022
摘要： A combined fluid injection and inflation system is disclosed and includes a fluid delivery system including at least one pressurizing device, a fluid path, and a control unit. The fluid path is adapted to connect the pressurizing device to a patient via a catheter including a balloon and inserted in the patient. The control unit is operable to control the fluid delivery system. In operation, the control unit selectively actuates the fluid delivery system to operate in a fluid injection mode or in a balloon inflation mode. In the fluid injection mode the pressurizing device delivers fluid to the fluid path for a fluid injection procedure. In the balloon inflation mode, the pressurizing device delivers fluid to the fluid path for inflating the balloon associated with the catheter. An operator control may be connected to the control unit for controlling the fluid delivery system and may be a handheld device.
摘要翻译： 公开了组合的流体注入和充气系统，并且包括包括至少一个加压装置，流体路径和控制单元的流体输送系统。 流体路径适于经由包括球囊并且插入患者体内的导管将加压装置连接到患者。 控制单元可操作以控制流体输送系统。 在操作中，控制单元选择性地致动流体输送系统以流体注射模式或气球充气模式操作。 在流体注射模式中，加压装置将流体输送到流体路径用于流体注射程序。 在球囊膨胀模式中，加压装置将流体输送到流体路径，用于使与导管相关联的球囊膨胀。 操作员控制可以连接到控制单元以控制流体输送系统，并且可以是手持装置。
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公开(公告)号：US20070106208A1
公开(公告)日：2007-05-10
申请号：US11460635
申请日：2006-07-28
申请人： Arthur Uber , Frederick Trombley , Eugene Gelblum , Edward Rhinehart , David Reilly , Page Cedarholm , Kevin Cowan , Mark Trocki , Alan Hirschman
发明人： Arthur Uber , Frederick Trombley , Eugene Gelblum , Edward Rhinehart , David Reilly , Page Cedarholm , Kevin Cowan , Mark Trocki , Alan Hirschman
IPC分类号： A61M31/00 , A01N1/02 , C12M1/12 , C12M1/24 , B65D25/04 , A01N1/00 , C12M3/00 , B65D1/24 , B65D1/36 , B65D57/00 , B65D85/00
CPC分类号： A61J1/1443 , A61J1/1456 , A61J1/1475 , A61M5/142 , A61M5/1723 , A61M5/3145 , A61M31/005 , B01L3/502 , B01L2300/044 , B01L2300/0681 , G06F19/3468
摘要： A system for injecting an injectate into patient includes a first pressurizable container for holding the injectate; a patient interface in fluid connection with the first pressurizable container, the patient interface being adapted to pass the injectate into tissue of the patient; a powered injector in operative connection with the first pressurizable container to pressurize the injectate; a controller system in operative connection with powered injector; and a stereotactic localization frame adapted to be placed in operative connection with the patient interface to assist in controlling localization of the patient interface. A system for processing cells (and/or other injectate components) includes a container and a plunger adapted to be slidably positioned within the container. The system includes at least one inlet port through which a fluid can enter the system and at least one effluent port through which an effluent can exit the system. The plunger section forms a sealing engagement with the inner wall of the container such that rearward motion of the plunger is adapted to draw fluid into the system via the inlet and forward motion of the plunger is adapted to force effluent out of the system via the effluent port.
摘要翻译： 用于将注射器注射到患者体内的系统包括用于保持注射器的第一可加压容器; 与所述第一可加压容器流体连接的患者接口，所述患者接口适于将所述注射器通入患者的组织; 动力注射器，其与所述第一可加压容器可操作地连接以对所述注射器加压; 与动力注射器操作连接的控制器系统; 以及适于与病人界面操作连接的立体定向定位框架，以协助控制患者界面的定位。 用于处理细胞（和/或其它注射组分）的系统包括适于可滑动地定位在容器内的容器和柱塞。 该系统包括至少一个入口，流体可以通过该入口进入系统和至少一个流出物端口，流出物可通过该至少一个出口端口离开系统。 柱塞部分形成与容器的内壁的密封接合，使得柱塞的向后运动适于通过入口将流体引入系统，并且柱塞的向前运动适于通过流出物强制流出系统的流出物 港口。
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公开(公告)号：US20080015505A1
公开(公告)日：2008-01-17
申请号：US11624933
申请日：2007-01-19
IPC分类号： A61M1/00
摘要： A tubing set includes a length of tubing having at least a section thereof that is fabricated to function with an infusion pump. The tubing set further preferably includes a first valve that is removably connected to the length of tubing on a first end thereof. The first valve is preferably in a closed state when disconnected from the length of tubing. The tubing set also preferably includes a second valve on a second end thereof. The second valve is preferably in a closed state until connected to another fluid path component. The tubing set is preferably suitable for use in an MR environment. A method of replacing at least a first infusion pump in connection with a patient with at least a second infusion pump includes the steps: closing a length of patient tubing connected to a patient to prevent backflow of blood therethrough, the patient tubing being in fluid communication at a first end thereof with a length of administration tubing, the administration tubing being in operative connection with the first infusion pump and being in fluid connection with a source of fluid, the patient tubing being in fluid connection with a patient catheter at a second end thereof; disconnecting the patient tubing from the administration tubing; connecting an intermediate length of tubing to the administration tubing, the intermediate tubing including at least a section thereof that is fabricated to function with the second infusion pump; placing the second infusion pump in operative connection with the intermediate tubing; removing the first infusion pump from operative connection with the administration tubing; and connecting the intermediate tubing to the patient tubing.
摘要翻译： 管组包括具有至少其一部分的管的长度，其被制造成与输注泵一起起作用。 管组还优选地包括第一阀，其可拆卸地连接到其第一端上的管道长度。 当与管道的长度断开时，第一阀优选处于关闭状态。 管道组件还优选地包括在其第二端上的第二阀。 第二阀优选地处于关闭状态，直到连接到另一个流体路径部件。 管组优选适用于MR环境。 用至少第二输液泵替代与患者相关的至少第一输注泵的方法包括以下步骤：闭合连接到患者的一段长度的患者管线，以防止血液通过其中流动，患者管路处于流体连通状态 在其第一端具有一定长度的给药管，所述给药管与所述第一输注泵可操作地连接并且与流体源流体连接，所述患者管与第二端的患者导管流体连接 的; 从患者管路断开患者管路; 将管道的中间长度连接到所述管理管道，所述中间管道包括制造成与所述第二输注泵一起起作用的至少一部分; 将所述第二输液泵放置成与所述中间管道有效连接; 将所述第一输注泵从所述管道管的操作连接中移除; 并将中间管连接到患者管。
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公开(公告)号：US20060184124A1
公开(公告)日：2006-08-17
申请号：US11336150
申请日：2006-01-21
申请人： Kevin Cowan , David Reilly , Joseph Fularz , Paul Swartz , Mark Trocki , David Mishler
发明人： Kevin Cowan , David Reilly , Joseph Fularz , Paul Swartz , Mark Trocki , David Mishler
IPC分类号： A61M37/00
CPC分类号： A61M5/007 , A61M5/14546 , A61M5/14566 , A61M5/16827 , A61M2005/14506
摘要： An injector for injection a fluid into a patient, including: a first pressurizing mechanism adapted to operatively connect with a first fluid container to pressurize fluid therein; at least a second pressurizing mechanism to operatively connect with a second fluid container to pressurize a fluid therein; a single drive; and a transmission to control how power from the drive is distributed to the first pressurizing mechanism of the first container and to the second pressurizing mechanism of the second container to control injection of fluid from the first container and from the second container. The drive can, for example, be an electric motor or other drive.
摘要翻译： 一种用于将流体注射到患者体内的注射器，包括：第一加压机构，其适于与第一流体容器可操作地连接以对其中的流体加压; 至少第二加压机构，用于与第二流体容器可操作地连接以对其中的流体加压; 单个驱动器 以及变速器，用于控制来自驱动器的动力如何分配到第一容器的第一加压机构和第二容器的第二加压机构，以控制来自第一容器和第二容器的流体的喷射。 驱动器可以例如是电动机或其他驱动器。
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5.发明授权Apparatus and methods for delivery of fluid injection boluses to patients and handling harmful fluids 有权用于向患者输送流体注射剂并处理有害流体的装置和方法公开(公告)号：US09056200B2
公开(公告)日：2015-06-16
申请号：US12996520
申请日：2009-06-05
申请人： Arthur E. Uber, III , Mark Trocki , Marc A. Mabie , Larry McCutchan , L. George Siddoway , Kevin P. Cowan , Lisa M. Coates , John F. Kalafut , Aaron Hughes , David M. Griffiths , Peter Twichell , Julie Gulick , Frederick W. Trombley, III
发明人： Arthur E. Uber, III , Mark Trocki , Marc A. Mabie , Larry McCutchan , L. George Siddoway , Kevin P. Cowan , Lisa M. Coates , John F. Kalafut , Aaron Hughes , David M. Griffiths , Peter Twichell , Julie Gulick , Frederick W. Trombley, III
CPC分类号： A61N5/1007 , A61M5/007 , A61M5/16827 , A61M5/1785 , A61M2005/1402 , A61M2202/0225 , A61M2202/049 , A61M2206/11 , A61M2206/18 , Y10T137/0318
摘要： A hazardous fluid transport container and a hazardous fluid delivery system are disclosed. The hazardous fluid transport container includes a housing enclosing an at least partially shielded enclosure. First and second fluid path elements are disposed within the housing, with the first fluid path element and second fluid path element fluidly coupled together. A pump unit may be provided for dispensing fluid from the first and second fluid path elements optionally into a third fluid path element. Also, methods for priming the hazardous fluid transport container and for mitigating laminar flow injection bolus spreading are disclosed. Additionally, disclosed is a radioactive fluid transport container for a syringe or other container. The radioactive fluid transport container allows the syringe or container to be used in an injection procedure without removal from the container.
摘要翻译： 公开了一种危险流体输送容器和危险流体输送系统。 危险流体输送容器包括封闭至少部分屏蔽的外壳的壳体。 第一和第二流体通道元件设置在壳体内，第一流体路径元件和第二流体路径元件流体耦合在一起。 可以提供泵单元，用于将流体从第一和第二流体路径元件任选地分配到第三流体路径元件中。 此外，公开了用于引燃危险流体输送容器和减轻层流注射团块扩散的方法。 此外，公开了一种用于注射器或其他容器的放射性流体输送容器。 放射性流体输送容器允许注射器或容器在注射过程中使用而不从容器中取出。
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公开(公告)号：US07670315B2
公开(公告)日：2010-03-02
申请号：US11336150
申请日：2006-01-21
申请人： Kevin P. Cowan , David M. Reilly , Joseph J. Fularz , Paul J. Swartz , Mark Trocki , David A. Mishler
发明人： Kevin P. Cowan , David M. Reilly , Joseph J. Fularz , Paul J. Swartz , Mark Trocki , David A. Mishler
CPC分类号： A61M5/007 , A61M5/14546 , A61M5/14566 , A61M5/16827 , A61M2005/14506
摘要： An injector for injection a fluid into a patient, including: a first pressurizing mechanism adapted to operatively connect with a first fluid container to pressurize fluid therein; at least a second pressurizing mechanism to operatively connect with a second fluid container to pressurize a fluid therein; a single drive; and a transmission to control how power from the drive is distributed to the first pressurizing mechanism of the first container and to the second pressurizing mechanism of the second container to control injection of fluid from the first container and from the second container. The drive can, for example, be an electric motor or other drive.
摘要翻译： 一种用于将流体注射到患者体内的注射器，包括：第一加压机构，其适于与第一流体容器可操作地连接以对其中的流体加压; 至少第二加压机构，用于与第二流体容器可操作地连接以对其中的流体加压; 单个驱动器 以及变速器，用于控制来自驱动器的动力如何分配到第一容器的第一加压机构和第二容器的第二加压机构，以控制来自第一容器和第二容器的流体的喷射。 驱动器可以例如是电动机或其他驱动器。
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公开(公告)号：US20090050216A1
公开(公告)日：2009-02-26
申请号：US12258505
申请日：2008-10-27
IPC分类号： F16K15/00
CPC分类号： A61M39/24 , A61M5/14546 , A61M5/16827 , A61M39/223 , A61M39/228 , A61M2039/2473 , A61M2039/2486 , A61M2039/2493 , Y10T137/2567 , Y10T137/2569 , Y10T137/2572 , Y10T137/2622 , Y10T137/7838 , Y10T137/7843 , Y10T137/7849 , Y10T137/86726 , Y10T137/87338 , Y10T137/87555
摘要： A valve system for use in a system including a first source of a first pressurized fluid and a second source of a second pressurized fluid includes a valve housing including a first inlet port adapted to be placed in fluid connection with the first source, a second inlet port adapted to be placed in fluid connection with the second source and an outlet port. The valve system further includes a backflow prevention system to prevent flow of the first pressurized fluid through the second inlet and to prevent flow of the second pressurized fluid through the first inlet port. The valve system is adapted to provide a fluid path between at least the first inlet port and the outlet port to enable fluid to be drawn from the outlet port to the first inlet port. Several of the valve systems of the present invention provide for flow from the first inlet port to the outlet port and concurrent flow from the second inlet port to the outlet port.
摘要翻译： 一种用于包括第一加压流体的第一源和第二加压流体的第二源的系统的阀系统包括阀壳体，其包括适于与第一源流体连接的第一入口端口，第二入口 端口适于与第二源和出口端口流体连接。 阀系统还包括防止流体流动的第一加压流体通过第二入口并防止第二加压流体通过第一入口流动的防回流系统。 阀系统适于在至少第一入口和出口之间提供流体路径，以使流体能够从出口到第一入口端口被抽出。 本发明的几个阀门系统提供从第一入口到出口的流动以及从第二入口到出口的并流。
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公开(公告)号：US20080294096A1
公开(公告)日：2008-11-27
申请号：US12092448
申请日：2006-11-06
申请人： Arthur E. Uber, III , Alan D. Hirschman , Evan Facher , Eugene A. Gelblum , David M. Griffiths , Edward J. Rhinehart , David M. Reilly , Kevin P. Cowan , Page Cedarholm , Barry L. Tucker , Mark Trocki , David Mishler , Henry E. Bartony, JR. , Robert Parks
发明人： Arthur E. Uber, III , Alan D. Hirschman , Evan Facher , Eugene A. Gelblum , David M. Griffiths , Edward J. Rhinehart , David M. Reilly , Kevin P. Cowan , Page Cedarholm , Barry L. Tucker , Mark Trocki , David Mishler , Henry E. Bartony, JR. , Robert Parks
IPC分类号： A61M5/168
CPC分类号： A61M5/142 , A61M5/1452 , A61M5/1723 , A61M5/3291 , A61M25/007 , A61M25/04 , A61M31/005 , A61M2025/0089 , A61M2025/009 , A61M2025/0092
摘要： A system for delivering a fluid comprising cells to tissue of a patient, includes: a least a first container for holding an injection fluid in which the agent is carried; a first powered drive in operative connection with the container, the first powered drive being operable to pressurize contents of the container; a control system in operative connection with the first powered drive and operative to control the first powered drive; a fluid path in fluid connection with the container, the fluid path including a patient interface adapted to deposit the cells within tissue of the patient; a sensor system; and a communication system in connection with at least the control system and the sensor system. The communication system is adapted to provide information to the control system. The control system in adapted to transmit a control signal to at least the first powered drive based at least in part on information provided to the control system. The cells can for example be pregenitor cells or stem cells.
摘要翻译： 一种用于将包含细胞的流体输送到患者的组织的系统，包括：用于保持其中携带有药剂的注射液体的至少第一容器; 与容器操作性连接的第一动力驱动器，第一动力驱动器可操作以对容器的内容物进行加压; 控制系统，其与第一动力驱动器操作连接并且可操作以控制第一动力驱动; 与容器流体连接的流体路径，流体路径包括适于将细胞沉积在患者组织内的患者界面; 传感器系统; 以及至少与控制系统和传感器系统相关的通信系统。 通信系统适于向控制系统提供信息。 控制系统适于至少部分地基于提供给控制系统的信息将控制信号发送到至少第一动力驱动器。 细胞可以例如是前体细胞或干细胞。
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公开(公告)号：US07414382B2
公开(公告)日：2008-08-19
申请号：US11733215
申请日：2007-04-10
IPC分类号： H02J7/00
CPC分类号： H02J7/0068 , A61B5/0046 , A61M5/007 , A61M5/14546 , A61M2205/8206 , A61M2205/8237 , H02J7/045
摘要： A battery charger system, for use with an injector system, comprises a power supply and a battery pack. The power supply converts AC power to DC power. The battery pack includes a battery and a charging module. The module monitors the operating mode of the injector system. When the battery pack is disconnected from the injection control unit, the module enables the power supply to charge the battery with DC power. When the battery pack is connected to the injection control unit: (A) upon detecting the injector system in an idle mode, the module routes DC power from the power supply to both the battery for charging thereof and the injection control unit for operation thereof; and (B) upon detecting the injector system in a non-idle mode, the module prevents the power supply from charging the battery and enables the battery to provide DC power to the injection control unit.
摘要翻译： 与注射器系统一起使用的电池充电器系统包括电源和电池组。 电源将交流电转换成直流电源。 电池组包括电池和充电模块。 模块监控喷油器系统的运行模式。 当电池组与注射控制单元断开连接时，该模块可使电源以直流电为电池充电。 当电池组连接到喷射控制单元时：（A）在空气模式下检测到喷射器系统时，该模块将来自电源的直流电力传送到用于充电的电池和用于其操作的喷射控制单元; 和（B）当在非空闲模式下检测到喷射器系统时，该模块防止电源对电池充电并使电池能够向喷射控制单元提供直流电力。
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公开(公告)号：US07224143B2
公开(公告)日：2007-05-29
申请号：US10723183
申请日：2003-11-26
IPC分类号： H01M10/46
CPC分类号： H02J7/0068 , A61B5/0046 , A61M5/007 , A61M5/14546 , A61M2205/8206 , A61M2205/8237 , H02J7/045
摘要： A battery charger system, for use with an injector system, comprises a power supply and a battery pack. The power supply converts AC power to DC power. The battery pack includes a battery and a charging module. The module monitors the operating mode of the injector system. When the battery pack is disconnected from the injection control unit, the module enables the power supply to charge the battery with DC power. When the battery pack is connected to the injection control unit: (A) upon detecting the injector system in an idle mode, the module routes DC power from the power supply to both the battery for charging thereof and the injection control unit for operation thereof; and (B) upon detecting the injector system in a non-idle mode, the module prevents the power supply from charging the battery and enables the battery to provide DC power to the injection control unit.
摘要翻译： 与注射器系统一起使用的电池充电器系统包括电源和电池组。 电源将交流电转换成直流电源。 电池组包括电池和充电模块。 模块监控喷油器系统的运行模式。 当电池组与注射控制单元断开连接时，该模块可使电源以直流电为电池充电。 当电池组连接到喷射控制单元时：（A）在空气模式下检测到喷射器系统时，模块将来自电源的直流电力传送到用于充电的电池和用于操作的注射控制单元; 和（B）当在非空闲模式下检测到喷射器系统时，该模块防止电源对电池充电并使电池能够向喷射控制单元提供直流电力。
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