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    BRAINSTORMING IN A CLOUD ENVIRONMENT
    2.
    发明申请
    BRAINSTORMING IN A CLOUD ENVIRONMENT 有权
    在云端环境中发挥作用

    公开(公告)号：US20130326346A1

    公开(公告)日：2013-12-05

    申请号：US13588773

    申请日：2012-08-17

    申请人： Zheren Zhu ,  Yongyuan Shen ,  Fu Zhao ,  Yingyu Chen ,  Bin Dong ,  Zheng Long Wei ,  Hui Wang

    发明人： Zheren Zhu ,  Yongyuan Shen ,  Fu Zhao ,  Yingyu Chen ,  Bin Dong ,  Zheng Long Wei ,  Hui Wang

    IPC分类号： G06F15/16 ,  G06F17/30 ,  G06F17/24

    CPC分类号： G06Q10/101 ,  H04L67/10

    摘要： The embodiments provide a cloud brainstorming service implemented on at least one cloud server. The brainstorming service includes a message service component configured to receive a plurality of ideas, over a network, from one or more users of devices. The users represent members of a brainstorming session. The brainstorming service also includes a brainstorming logic component configured to process the plurality of ideas and store the plurality of processed ideas in an in-memory database system, and a clustering component configured to retrieve the plurality of processed ideas from the in-memory database system and arrange the plurality of processed ideas into one or more clusters, where each cluster is a group of similar ideas. The message service component is configured to provide the plurality of processed ideas that are arranged into the one or more clusters, over the network, to the one or more users for display.

    摘要翻译： 这些实施例提供了在至少一个云服务器上实现的云头脑风暴服务。 头脑风暴服务包括消息服务组件，其被配置为从设备的一个或多个用户通过网络接收多个想法。 用户代表头脑风暴会议的成员。 头脑风暴服务还包括头脑风暴逻辑组件，其被配置为处理多个想法并将多个处理的想法存储在存储器内数据库系统中;以及集群组件，被配置为从存储器内数据库系统中检索多个处理的想法 并将多个处理的想法排列成一个或多个集群，其中每个集群是一组相似的观点。 消息服务组件被配置为将被布置在一个或多个集群中的多个经处理的想法通过网络提供给一个或多个用户进行显示。

    Polycosanols from Ericerus pela wax
    3.
    发明授权
    Polycosanols from Ericerus pela wax 有权
    来自梨果的聚山梨醇蜡

    公开(公告)号：US06683116B1

    公开(公告)日：2004-01-27

    申请号：US10356676

    申请日：2003-01-31

    申请人： Qi Jia ,  Ji-Fu Zhao

    发明人： Qi Jia ,  Ji-Fu Zhao

    IPC分类号： A01N3100

    CPC分类号： A61K31/045 ,  Y10S514/925 ,  A61K2300/00

    摘要： The present invention provides a novel method for the preparation of a unique profile of primary aliphatic alcohols, having 24 to 30 carbon atoms, from the wax secreted by the insect Ericerus pela. Included in the present invention is the composition of matter, referred to herein as “polycosanol” produced by the method of this invention. The polycosanol composition is comprised primarily of the four primary aliphatic alcohols, tetracosanol, hexacosanol, octacosanol and triacontanol. Further included in this invention is the use of said composition of matter for the prevention and treatment of obesity, syndrome X, diabetes, hypercholesterolemia, atherosclerotic complications, ischemia and thrombosis.

    摘要翻译： 本发明提供了一种新颖的方法，用于制备具有24至30个碳原子的伯脂肪醇，其特征在于由昆虫螨属分泌的蜡。 本发明中包括由本发明的方法生产的物质组合物，这里称为“多可醇”。 多糖醇组合物主要由四种脂族醇，二十四烷醇，二十四烷醇，三十烷醇组成。 本发明还包括所述物质组合物用于预防和治疗肥胖症，综合征X，糖尿病，高胆固醇血症，动脉粥样硬化并发症，局部缺血和血栓形成的用途。

    Chromones as therapeutic agents
    4.
    发明授权
    Chromones as therapeutic agents 有权
    色酮作为治疗剂

    公开(公告)号：US08852657B2

    公开(公告)日：2014-10-07

    申请号：US11971523

    申请日：2008-01-09

    申请人： Ji-Fu Zhao ,  Julie Tseng-Crank ,  Mesfin Yimam ,  Qi Jia

    发明人： Ji-Fu Zhao ,  Julie Tseng-Crank ,  Mesfin Yimam ,  Qi Jia

    IPC分类号： A61K36/886 ,  A61K36/00 ,  A61K36/704 ,  A61K31/7048 ,  A61K31/35 ,  A61K31/352 ,  A61K36/48 ,  A61K36/38 ,  A61K36/489

    CPC分类号： A61K31/352 ,  A61K31/35 ,  A61K31/7048 ,  A61K36/38 ,  A61K36/48 ,  A61K36/489 ,  A61K36/704 ,  A61K36/886

    摘要： The identification and isolation of chromones and novel chromone compositions from plant sources that exhibit up-regulation of adiponectin production by adipocytes and the normalization of virtually hundreds of genes related to glucose and fatty acid metabolic and signaling pathways. The chromone compositions are effective in enhancing adiponectin production by adipocytes and regulating genes involved in fatty acid biosynthesis, mitochondrial β-oxidation of fatty acids, steroid biosynthesis, gluconeogenesis, fat transport, PPARα/RXRα liver signaling and xenobiotic metabolism. The chromone compositions can be used to increase insulin sensitivity, improve glucose tolerance, lower triglyceride levels and balance glucose levels in mammals. Included are methods for the prevention and treatment of a variety of diseases and conditions including, but not limited to insulin resistance, glucose intolerance, hyperglycemia, metabolic syndromes, dyslipidemia, and hypertriglyceridemia.

    摘要翻译： 鉴定和分离来自植物来源的色酮和新的色酮组合物，其表现出脂肪细胞脂联素产生的上调，以及与葡萄糖和脂肪酸代谢和信号通路相关的几乎几百个基因的归一化。 色酮组合物可有效增强脂肪细胞的脂联素产生，调节脂肪酸生物合成，线粒体和脂肪酸的氧化，类固醇生物合成，糖异生，脂肪转运，PPARα/RXRα肝脏信号转导和异种生物代谢等因素的调控。 色酮组合物可用于增加胰岛素敏感性，改善葡萄糖耐量，降低甘油三酯水平和平衡哺乳动物中的葡萄糖水平。 包括预防和治疗各种疾病和病症的方法，包括但不限于胰岛素抵抗，葡萄糖不耐受，高血糖症，代谢综合征，血脂异常和高甘油三酯血症。

    Chromones As Therapeutic Agents
    6.
    发明申请
    Chromones As Therapeutic Agents 有权
    色酮作为治疗剂

    公开(公告)号：US20080166438A1

    公开(公告)日：2008-07-10

    申请号：US11971523

    申请日：2008-01-09

    申请人： Ji-Fu Zhao ,  Julie Tseng-Crank ,  Mesfin Yimam ,  Qi Jia

    发明人： Ji-Fu Zhao ,  Julie Tseng-Crank ,  Mesfin Yimam ,  Qi Jia

    IPC分类号： A61K31/352 ,  A61K31/7048 ,  A61P3/00 ,  A61K36/886

    CPC分类号： A61K31/352 ,  A61K31/35 ,  A61K31/7048 ,  A61K36/38 ,  A61K36/48 ,  A61K36/489 ,  A61K36/704 ,  A61K36/886

    摘要： The present invention describes the identification and isolation of chromones and novel chromone compositions from plant sources that exhibit up-regulation of adiponectin production by adipocytes and the normalization of virtually hundreds of genes related to glucose and fatty acid metabolic and signaling pathways. The chromone compositions are effective in enhancing adiponectin production by adipocytes and regulating genes involved in fatty acid biosynthesis, mitochondrial β-oxidation of fatty acids, steroid biosynthesis, gluconeogenesis, fat transport, PPARα/RXRα liver signaling and xenobiotic metabolism. The chromone compositions can be used to increase insulin sensitivity, improve glucose tolerance, lower triglyceride levels and balance glucose levels in mammals. Included in the present invention are methods for the prevention and treatment of a variety of diseases and conditions including, but not limited to insulin resistance, glucose intolerance, hyperglycemia, metabolic syndromes, dyslipidemia, and hypertriglyceridemia.

    摘要翻译： 本发明描述了鉴定和分离来自植物来源的色酮和新的色酮组合物，其显示脂肪细胞脂联素产生的上调和几乎几百个与葡萄糖和脂肪酸代谢和信号通路相关基因的标准化。 色酮组合物有效促进脂肪细胞的脂联素产生，调节脂肪酸生物合成，脂肪酸线粒体β-氧化，类固醇生物合成，糖异生，脂肪转运，PPARalpha / RXRalpha肝信号转导和异种生物代谢的基因。 色酮组合物可用于增加胰岛素敏感性，改善葡萄糖耐量，降低甘油三酯水平和平衡哺乳动物中的葡萄糖水平。 本发明包括预防和治疗各种疾病和病症的方法，包括但不限于胰岛素抵抗，葡萄糖不耐受，高血糖症，代谢综合症，血脂异常和高甘油三酯血症。

    Polycosanols from Ericerus pela wax
    7.
    发明申请
    Polycosanols from Ericerus pela wax 审中-公开
    来自梨果的聚山梨醇蜡

    公开(公告)号：US20050239904A1

    公开(公告)日：2005-10-27

    申请号：US11157992

    申请日：2005-06-21

    申请人： Qi Jia ,  Ji-Fu Zhao

    发明人： Qi Jia ,  Ji-Fu Zhao

    IPC分类号： A61K31/045 ,  A61K35/63 ,  A61K35/64

    CPC分类号： A61K31/045 ,  A61K35/63 ,  Y10S514/925 ,  A61K2300/00

    摘要： The present invention provides a novel method for the preparation of a unique profile of primary aliphatic alcohols, having 24 to 30 carbon atoms, from the wax secreted by the insect Ericerus pela. Included in the present invention is the composition of matter, referred to herein as “polycosanol” produced by the method of this invention. The polycosanol composition is comprised primarily of the four primary aliphatic alcohols, tetracosanol, hexacosanol, octacosanol and triacontanol. Further included in this invention is the use of said composition of matter for the prevention and treatment of obesity, syndrome X, diabetes, hypercholesterolemia, atherosclerotic complications, ischemia and thrombosis.

    摘要翻译： 本发明提供了一种新颖的方法，用于制备具有24至30个碳原子的伯脂肪醇，其特征在于由昆虫螨属分泌的蜡。 本发明中包括由本发明的方法生产的物质组合物，这里称为“多可醇”。 多糖醇组合物主要由四种脂族醇，二十四烷醇，二十四烷醇，三十烷醇组成。 本发明还包括所述物质组合物用于预防和治疗肥胖症，综合征X，糖尿病，高胆固醇血症，动脉粥样硬化并发症，局部缺血和血栓形成的用途。

    Polycosanols from Ericerus pela wax
    9.
    发明授权
    Polycosanols from Ericerus pela wax 有权

    公开(公告)号：US07034060B2

    公开(公告)日：2006-04-25

    申请号：US10991340

    申请日：2004-11-16

    申请人： Qi Jia ,  Ji-Fu Zhao

    发明人： Qi Jia ,  Ji-Fu Zhao

    IPC分类号： A01N31/00 ,  A61K31/045

    CPC分类号： A61K31/045 ,  A61K35/63 ,  Y10S514/925 ,  A61K2300/00

    摘要： The present invention provides a novel method for the preparation of a unique profile of primary aliphatic alcohols, having 24 to 30 carbon atoms, from the wax secreted by the insect Ericerus pela. Included in the present invention is the composition of matter, referred to herein as “polycosanol” produced by the method of this invention. The polycosanol composition is comprised primarily of the four primary aliphatic alcohols, tetracosanol, hexacosanol, octacosanol and triacontanol. Further included in this invention is the use of said composition of matter for the prevention and treatment of obesity, syndrome X, diabetes, hypercholesterolemia, atherosclerotic complications, ischemia and thrombosis.

    Polycosanols from Ericerus pela wax
    10.
    发明授权
    Polycosanols from Ericerus pela wax 失效
    来自梨果的聚山梨醇蜡

    公开(公告)号：US06984666B2

    公开(公告)日：2006-01-10

    申请号：US10991179

    申请日：2004-11-16

    申请人： Qi Jia ,  Ji-Fu Zhao

    发明人： Qi Jia ,  Ji-Fu Zhao

    IPC分类号： A01N31/00 ,  A61K31/045

    CPC分类号： A61K31/045 ,  Y10S514/925 ,  A61K2300/00

    摘要： The present invention provides a novel method for the preparation of a unique profile of primary aliphatic alcohols, having 24 to 30 carbon atoms, from the wax secreted by the insect Ericerus pela. Included in the present invention is the composition of matter, referred to herein as “polycosanol” produced by the method of this invention. The polycosanol composition is comprised primarily of the four primary aliphatic alcohols, tetracosanol, hexacosanol, octacosanol and triacontanol. Further included in this invention is the use of said composition of matter for the prevention and treatment of obesity, syndrome X, diabetes, hypercholesterolemia, atherosclerotic complications, ischemia and thrombosis.

    摘要翻译： 本发明提供了一种新颖的方法，用于制备具有24至30个碳原子的伯脂肪醇，其特征在于由昆虫螨属分泌的蜡。 本发明中包括由本发明的方法生产的物质组合物，这里称为“多可醇”。 多糖醇组合物主要由四种脂族醇，二十四烷醇，二十四烷醇，三十烷醇组成。 本发明还包括所述物质组合物用于预防和治疗肥胖症，综合征X，糖尿病，高胆固醇血症，动脉粥样硬化并发症，局部缺血和血栓形成的用途。