公开(公告)号：US4388478A

公开(公告)日：1983-06-14

申请号：US316800

申请日：1981-10-30

申请人： Akihide Kudoh ,  Motoo Kawamata ,  Kazushi Ohshima ,  Makoto Kotani ,  Takeshi Tsuda ,  Fukuichi Aoki

发明人： Akihide Kudoh ,  Motoo Kawamata ,  Kazushi Ohshima ,  Makoto Kotani ,  Takeshi Tsuda ,  Fukuichi Aoki

IPC分类号： B01J23/00 ,  B01J23/32 ,  B01J23/34 ,  C07B61/00 ,  C07C27/00 ,  C07C37/16 ,  C07C39/06 ,  C07C67/00

CPC分类号： B01J23/32 ,  C07C37/16

摘要： This invention relates to a process for the selective ortho-alkylation of a phenolic compound having at least one ortho-positioned hydrogen atom by catalytically reacting the phenolic compound with an alcohol in the vapor phase. In this process, the reaction of the phenolic compound with the alcohol is carried out at a temperature of from 300.degree. to 550.degree. C. in the presence of a catalyst containing manganese oxide and one or more additives selected from group (A) consisting of germanium oxide, tin oxide and lead oxide, or a catalyst containing manganese oxide, one or more additives selected from the aforesaid group (A), and one or more additives selected from group (B) consisting of alkali metal oxides and alkaline earth metal oxides. The catalyst used in this invention exhibits not only excellent catalytic activity in the selective ortho-alkylation of phenols, continuous stability of the activity, good shapeability and good mechanical strength but also effective utilization of alcohols.

摘要翻译： 本发明涉及一种通过使酚类化合物与气相中的醇催化反应，使具有至少一个邻位氢原子的酚类化合物选择性正烷基化的方法。 在该方法中，酚类化合物与醇的反应在含有氧化锰和一种或多种选自（A）组成的催化剂的催化剂存在下，在300〜550℃的温度下进行。 或者含有氧化锰的催化剂，选自上述组（A）的一种或多种添加剂和选自由碱金属氧化物和碱土金属氧化物组成的组（B）的一种或多种添加剂 。 用于本发明的催化剂不仅在酚的选择性邻烷基化中表现出优异的催化活性，活性的连续稳定性，良好的成型性和良好的机械强度，而且有效地利用醇。