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公开(公告)号:US20100144544A1
公开(公告)日:2010-06-10
申请号:US12522237
申请日:2008-01-04
CPC分类号: G01N21/6428 , G01N2021/6441
摘要: Fluorescence Labelling This invention generally relates to techniques for fluorescence labelling, and to methods, apparatus and computer program code for processing fluorescence signal data. A method of determining respective first and second degree-of-labelling signals for different respective first and second fluorophores associated with a common entity, the method comprising: determining a first fluorescence signal from said first and second fluorophores under first conditions; determining a second fluorescence signal from said first and second fluorophores under second conditions different to said first conditions; and determining said first and second degree-of-labelling signals for said first and second fluorophores from said first and second fluorescence signals; and wherein said determining of said first and second degree-of-labelling signals is responsive to at least one coupling value (c12; c21) representing a coupling of energy between said fluorophores.
摘要翻译: 荧光标记本发明一般涉及用于荧光标记的技术,以及用于处理荧光信号数据的方法,装置和计算机程序代码。 确定与共同实体相关联的不同的相应的第一和第二荧光团的相应的第一和第二标记信号的方法,所述方法包括:在第一条件下从所述第一和第二荧光团确定第一荧光信号; 在与所述第一条件不同的第二条件下,从所述第一和第二荧光团确定第二荧光信号; 以及从所述第一和第二荧光信号确定所述第一和第二荧光团的所述第一和第二标记信号; 并且其中所述确定所述第一和第二标记符号信号响应于表示所述荧光团之间的能量耦合的至少一个耦合值(c12; c21)。
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公开(公告)号:US06229147B1
公开(公告)日:2001-05-08
申请号:US09051260
申请日:1998-09-03
IPC分类号: H01L31115
CPC分类号: G01T1/28 , G01T1/2942
摘要: There is disclosed an autoradiography system which includes an autoradiography sample, a substantially radioisotope free microchannel plate (MCP), and an MCP signal collection means, wherein the MCP directly measures beta particles from radioisotopes within the sample.
摘要翻译: 公开了一种放射自显影系统,其包括放射自显影样品,基本上不含放射性同位素的微通道板(MCP)和MCP信号采集装置,其中MCP直接测量样品内放射性同位素的β粒子。
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公开(公告)号:US07585624B2
公开(公告)日:2009-09-08
申请号:US10794397
申请日:2004-03-05
申请人: George William Fraser , Andrew David Holland , Gertrude Maria Schwarzacher , John Seymour Heslop-Harrison
发明人: George William Fraser , Andrew David Holland , Gertrude Maria Schwarzacher , John Seymour Heslop-Harrison
CPC分类号: G01N21/6456 , G01N2021/6441
摘要: A cryogenic detector is used for detection in a biological assay.
摘要翻译: 低温检测器用于生物测定中的检测。
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公开(公告)号:US07265359B2
公开(公告)日:2007-09-04
申请号:US10526823
申请日:2003-09-08
IPC分类号: G01T3/00
CPC分类号: G01T3/00
摘要: A method of detecting fast neutrons of energy greater than 5 MeV is provided. The method includes providing a neutron detector including a plate having plurality of detection sites disposed thereon which produce an electron output. The neutron detector is directly coupled to an electron detector without an intermediate scintillator layer. The detector is positioned so that neutrons are incident on the detector and the output of the electron detector is detected.
摘要翻译: 提供了一种检测能量大于5MeV的快中子的方法。 该方法包括提供一种中子检测器,其包括具有多个检测位置的板,该检测位置设置在其上,产生电子输出。 中子检测器直接耦合到没有中间闪烁体层的电子检测器。 探测器的定位使得中子入射到探测器上,并检测出电子探测器的输出。
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公开(公告)号:US20100032568A1
公开(公告)日:2010-02-11
申请号:US12539416
申请日:2009-08-11
申请人: George William Fraser , Andrew David Holland , Gertrude Maria Schwarzacher , John Seymour Heslop-Harrison
发明人: George William Fraser , Andrew David Holland , Gertrude Maria Schwarzacher , John Seymour Heslop-Harrison
CPC分类号: G01N21/6456 , G01N2021/6441
摘要: A cryogenic detector is used for detection in a biological assay.
摘要翻译: 低温检测器用于生物测定中的检测。
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公开(公告)号:US07173251B2
公开(公告)日:2007-02-06
申请号:US10433799
申请日:2001-12-04
IPC分类号: G01T1/24
CPC分类号: G01T1/2018 , A61B6/4258 , A61B6/508
摘要: There is disclosed a device for imaging radionuclide emissions comprising: a charge coupled device or CMOS active pixel sensor device; and a scintillator layer in direct contact with the charge coupled device or CMOS active pixel sensor device; in which the thickness of the scintillator layer is greater than 200 μm, preferably greater than 400 μm, most preferably about 500 μm.
摘要翻译: 公开了一种用于对放射性核素发射进行成像的装置,包括:电荷耦合器件或CMOS有源像素传感器器件; 以及与电荷耦合器件或CMOS有源像素传感器器件直接接触的闪烁体层; 其中闪烁体层的厚度大于200μm,优选大于400μm,最优选约500μm。
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