Antibodies and methods for making and using them
    1.
    发明授权
    Antibodies and methods for making and using them 有权
    用于制造和使用它们的抗体和方法

    公开(公告)号:US08945550B2

    公开(公告)日:2015-02-03

    申请号:US12487422

    申请日:2009-06-18

    IPC分类号: A61K39/395

    摘要: The invention provides antibodies, including chimeric human antibodies, recombinant antibodies, synthetic anti-bodies, and the nucleic acids encoding them, and methods for making and using these immunoglobulins. The invention provides recombinant and synthetic polypeptide and nucleic acid embodiments of these polypeptides and/or antibodies. The invention also provides polypeptides comprising, or consisting of, consensus human framework regions, or “Independently Consensused Frameworks (ICFs)”, nucleic acids encoding them, and libraries and kits comprising these ICFs and/or antibodies of the invention, individually and in combinatorial libraries and combinations.

    摘要翻译: 本发明提供抗体,包括嵌合人抗体,重组抗体,合成抗体和编码它们的核酸,以及制备和使用这些免疫球蛋白的方法。 本发明提供这些多肽和/或抗体的重组和合成多肽和核酸实施方案。 本发明还提供了包含共有人框架区或“独立共有框架(ICF)”的编码它们的核酸或包含本发明的这些ICF和/或抗体的文库和试剂盒的多肽,并且组合的多肽 图书馆和组合。

    Oscillating slide valve
    9.
    发明授权
    Oscillating slide valve 失效
    摆动滑阀

    公开(公告)号:US4089505A

    公开(公告)日:1978-05-16

    申请号:US740031

    申请日:1976-11-08

    CPC分类号: F16K3/10 F16K31/5286

    摘要: In an oscillating valve in which a slide plate is subjected to a swinging movement between an opening position in which it is clear of a flow passage and a closing position in which it is inserted in the flow path, and, in its closing position, is applied against a sealing surface by a sealing force to block the flow path, a single drive device is provided to produce both the swinging movement and the sealing force and the sealing force is produced by moving the slide plate perpendicular to the sealing surface only after the slide plate has reached the closing position associated with its swinging movement.

    摘要翻译: 在一个摆动阀中,其中滑动板在其中没有流动通道的打开位置和其中插入流路中的关闭位置之间经受摆动运动,并且在其关闭位置是 通过密封力施加到密封表面以阻塞流动路径,提供单个驱动装置以产生摆动运动和密封力,并且仅通过将滑板垂直于密封表面移动而产生密封力 滑板已经达到与其摆动相关联的关闭位置。