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![IMIDAZO[1,2-b]PYRIDAZINE-BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE](/abs-image/US/2013/09/19/US20130245021A1/abs.jpg.150x150.jpg)
1.发明申请公开(公告)号：US20130245021A1
公开(公告)日：2013-09-19
申请号：US13785271
申请日：2013-03-05
申请人： Yingzhi BI , Kenneth Gordon CARSON , Giovanni CIANCHETTA , Michael Alan GREEN , Godwin KUMI , Zhi LIANG , Ying Jade LIU , Alan MAIN , Yulian ZHANG , Gregory Glenn ZIPP
发明人： Yingzhi BI , Kenneth Gordon CARSON , Giovanni CIANCHETTA , Michael Alan GREEN , Godwin KUMI , Zhi LIANG , Ying Jade LIU , Alan MAIN , Yulian ZHANG , Gregory Glenn ZIPP
IPC分类号： C07D487/04
CPC分类号： C07D487/04 , A61K31/5025 , C07D241/04 , C07D401/14 , C07D403/14 , C07D498/18 , C07D519/00
摘要： Imidazo[1,2-b]pyridazine-based compounds of the formula: are disclosed, wherein R1, R2 and R3 are defined herein. Compositions comprising the compounds and methods of their use to treat, manage and/or prevent diseases and disorders mediated by mediated by adaptor associated kinase 1 activity are also disclosed.
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![Imidazo[1,2-b]pyridazine-based compounds, compositions comprising them, and methods of their use](/abs-image/US/2015/03/03/US08969565B2/abs.jpg.150x150.jpg)
2.发明授权Imidazo[1,2-b]pyridazine-based compounds, compositions comprising them, and methods of their use 有权咪唑并[1,2-b]哒嗪类化合物，包含它们的组合物及其使用方法公开(公告)号：US08969565B2
公开(公告)日：2015-03-03
申请号：US13785271
申请日：2013-03-05
申请人： Yingzhi Bi , Kenneth Gordon Carson , Giovanni Cianchetta , Michael Alan Green , Godwin Kumi , Zhi Liang , Ying Jade Liu , Alan Main , Yulian Zhang , Gregory Glenn Zipp
发明人： Yingzhi Bi , Kenneth Gordon Carson , Giovanni Cianchetta , Michael Alan Green , Godwin Kumi , Zhi Liang , Ying Jade Liu , Alan Main , Yulian Zhang , Gregory Glenn Zipp
IPC分类号： C07D241/04 , C07D401/14 , C07D403/14 , C07D487/04 , A61K31/5025
CPC分类号： C07D487/04 , A61K31/5025 , C07D241/04 , C07D401/14 , C07D403/14 , C07D498/18 , C07D519/00
摘要： Imidazo[1,2-b]pyridazine-based compounds of the formula: are disclosed, wherein R1, R2 and R3 are defined herein. Compositions comprising the compounds and methods of their use to treat, manage and/or prevent diseases and disorders mediated by mediated by adaptor associated kinase 1 activity are also disclosed.
摘要翻译： 公开了下式的咪唑并[1,2-b]哒嗪类化合物，其中R1，R2和R3如本文所定义。 还公开了包含化合物的组合物及其用于治疗，治疗和/或预防由衔接子相关激酶1活性介导的疾病和病症的方法。
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![Pyrazolo[1,5-a]pyrimidine-based compounds, compositions comprising them, and methods of their use](/abs-image/US/2015/02/03/US08946415B2/abs.jpg.150x150.jpg)
3.发明授权Pyrazolo[1,5-a]pyrimidine-based compounds, compositions comprising them, and methods of their use 有权吡唑并[1,5-a]嘧啶类化合物，包含它们的组合物及其用途公开(公告)号：US08946415B2
公开(公告)日：2015-02-03
申请号：US13785355
申请日：2013-03-05
申请人： Yingzhi Bi , Kenneth Gordon Carson , Giovanni Cianchetta , Michael Alan Green , Godwin Kumi , Alan Main , Yulian Zhang , Gregory Glenn Zipp
发明人： Yingzhi Bi , Kenneth Gordon Carson , Giovanni Cianchetta , Michael Alan Green , Godwin Kumi , Alan Main , Yulian Zhang , Gregory Glenn Zipp
IPC分类号： C07D487/04 , A61K31/519
CPC分类号： C07D487/04 , A61K31/519 , C07B59/002 , C07B2200/05
摘要： Pyrazolo[1,5-a]pyrimidine-based compounds of the formula: are disclosed, wherein R1, R2 and R3 are defined herein. Compositions comprising the compounds and methods of their use to treat, manage and/or prevent diseases and disorders mediated by adaptor associated kinase 1 activity are also disclosed.
摘要翻译： 公开了下式的吡唑并[1,5-a]嘧啶类化合物，其中R1，R2和R3在本文中定义。 还公开了包含化合物的组合物及其用于治疗，治疗和/或预防由衔接子相关激酶1活性介导的疾病和病症的方法。
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![PYRAZOLO[1,5-a]PYRIMIDINE-BASED COMPOUNDS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE](/abs-image/US/2013/09/26/US20130253194A1/abs.jpg.150x150.jpg)
4.发明申请公开(公告)号：US20130253194A1
公开(公告)日：2013-09-26
申请号：US13785355
申请日：2013-03-05
申请人： Yingzhi BI , Kenneth Gordon CARSON , Giovanni CIANCHETTA , Michael Alan GREEN , Godwin KUMI , Alan MAIN , Yulian ZHANG , Gregory Glenn ZIPP
发明人： Yingzhi BI , Kenneth Gordon CARSON , Giovanni CIANCHETTA , Michael Alan GREEN , Godwin KUMI , Alan MAIN , Yulian ZHANG , Gregory Glenn ZIPP
IPC分类号： C07D487/04
CPC分类号： C07D487/04 , A61K31/519 , C07B59/002 , C07B2200/05
摘要： Pyrazolo[1,5-a]pyrimidine-based compounds of the formula: are disclosed, wherein R1, R2 and R3 are defined herein. Compositions comprising the compounds and methods of their use to treat, manage and/or prevent diseases and disorders mediated by mediated by adaptor associated kinase 1 activity are also disclosed.
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