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17 条记录 (耗时 0.023 秒)

    Subsea Intervention Plug Pulling Device
    1.
    发明申请
    Subsea Intervention Plug Pulling Device 审中-公开
    海底干预拔插装置

    公开(公告)号：US20150136406A1

    公开(公告)日：2015-05-21

    申请号：US14082469

    申请日：2013-11-18

    申请人： Mauricio Baez ,  Raymond A. Stawaisz ,  John Lloyd Busby ,  Brian Saucier ,  Stephen Gregory Pierce ,  Walter Warren Weaver

    发明人： Mauricio Baez ,  Raymond A. Stawaisz ,  John Lloyd Busby ,  Brian Saucier ,  Stephen Gregory Pierce ,  Walter Warren Weaver

    IPC分类号： E21B23/00

    CPC分类号： E21B23/00 ,  E21B23/04 ,  E21B33/043 ,  E21B33/076

    摘要： A plug pulling device includes an elongated housing comprising a production tree connection interface, a shifting tool disposed within and along a substantial length the housing and comprising a distal end configured to couple to a tubing plug, and a seal disposed within the housing and formed around a portion of the shifting tool. The seal isolates a first portion of the housing from a second portion of the housing. The second portion of the housing is adjacent to the production tree connection interface. The shifting tool is configured to move partially in and out of the first portion of the housing when there is a pressure differential between the first portion of the housing and an environment external to the first portion of the housing.

    摘要翻译： 插头拉动装置包括细长壳体，该细长壳体包括生产树连接界面，设置在壳体内部并沿其长度大体上延伸的移动工具，并且包括构造成联接到管道塞的远端以及设置在壳体内并围绕 换档工具的一部分。 密封件将壳体的第一部分与壳体的第二部分隔离。 外壳的第二部分与生产树连接界面相邻。 当在壳体的第一部分和壳体的第一部分外部的环境之间存在压力差时，换档工具构造成部分地进出壳体的第一部分。

    HER-2 PEPTIDES AND VACCINES
    2.
    发明申请
    HER-2 PEPTIDES AND VACCINES 有权
    HER-2肽和疫苗

    公开(公告)号：US20130078270A1

    公开(公告)日：2013-03-28

    申请号：US13701814

    申请日：2011-05-23

    申请人： Helen Kim Cho ,  Siradanahalli Chandrasekharalah Guru ,  Van To Tsai ,  Brian Gregory Pierce

    发明人： Helen Kim Cho ,  Siradanahalli Chandrasekharalah Guru ,  Van To Tsai ,  Brian Gregory Pierce

    IPC分类号： C07K14/71

    CPC分类号： C07K14/71 ,  A61K39/0011 ,  A61K2039/53 ,  C07K14/82

    摘要： The present invention provides (a) isolated immunogenic HER-2 peptides capable of inducing immune responses against human HER-2 receptor; (b) isolated nucleic acid molecules encoding an isolated immunogenic HER-2 peptide; (c) plasmid constructs comprising a nucleic acid molecule encoding an isolated immunogenic HER-2 peptide; (d) vaccine compositions comprising an isolated immunogenic HER-2 peptide (e) vaccine compositions comprising an isolated nucleic acid molecule encoding an isolated immunogenic HER-2 peptide; and (f) methods of treating or preventing cancer, inhibiting abnormal cell proliferation, or eliciting an immune response against HER-2 protein in a mammal using (1) an isolated immunogenic HER-2 peptide, (2) nucleic acid molecule encoding an isolated immunogenic HER-2 peptide, or (3) a composition comprising an isolated immunogenic HER-2 peptide, or composition comprising a nucleic acid molecule encoding an isolated immunogenic HER-2 peptide.

    摘要翻译： 本发明提供（a）能够诱导针对人HER-2受体的免疫应答的分离的免疫原性HER-2肽; （b）编码分离的免疫原性HER-2肽的分离的核酸分子; （c）包含编码分离的免疫原性HER-2肽的核酸分子的质粒构建体; （d）包含分离的免疫原性HER-2肽（e）疫苗组合物的疫苗组合物，其包含编码分离的免疫原性HER-2肽的分离的核酸分子; 和（f）使用（1）分离的免疫原性HER-2肽，（2）编码分离的免疫原性HER-2肽的核酸分子来治疗或预防癌症，抑制异常细胞增殖或引起哺乳动物中HER-2蛋白的免疫应答的方法 免疫原性HER-2肽，或（3）包含分离的免疫原性HER-2肽或包含编码分离的免疫原性HER-2肽的核酸分子的组合物的组合物。

    HER-2 peptides and vaccines
    4.
    发明授权
    HER-2 peptides and vaccines 有权
    HER-2肽和疫苗

    公开(公告)号：US08895017B2

    公开(公告)日：2014-11-25

    申请号：US13701814

    申请日：2011-05-23

    申请人： Helen Kim Cho ,  Siradanahalli Chandrasekharalah Guru ,  Van To Tsai ,  Brian Gregory Pierce

    发明人： Helen Kim Cho ,  Siradanahalli Chandrasekharalah Guru ,  Van To Tsai ,  Brian Gregory Pierce

    IPC分类号： A61K39/00 ,  C07K14/71 ,  C07K14/82

    CPC分类号： C07K14/71 ,  A61K39/0011 ,  A61K2039/53 ,  C07K14/82

    摘要： The present invention provides (a) isolated immunogenic HER-2 peptides capable of inducing immune responses against human HER-2 receptor; (b) isolated nucleic acid molecules encoding an isolated immunogenic HER-2 peptide; (c) plasmid constructs comprising a nucleic acid molecule encoding an isolated immunogenic HER-2 peptide; (d) vaccine compositions comprising an isolated immunogenic HER-2 peptide (e) vaccine compositions comprising an isolated nucleic acid molecule encoding an isolated immunogenic HER-2 peptide; and (f) methods of treating or preventing cancer, inhibiting abnormal cell proliferation, or eliciting an immune response against HER-2 protein in a mammal using (1) an isolated immunogenic HER-2 peptide, (2) nucleic acid molecule encoding an isolated immunogenic HER-2 peptide, or (3) a composition comprising an isolated immunogenic HER-2 peptide, or composition comprising a nucleic acid molecule encoding an isolated immunogenic HER-2 peptide.

    摘要翻译： 本发明提供（a）能够诱导针对人HER-2受体的免疫应答的分离的免疫原性HER-2肽; （b）编码分离的免疫原性HER-2肽的分离的核酸分子; （c）包含编码分离的免疫原性HER-2肽的核酸分子的质粒构建体; （d）包含分离的免疫原性HER-2肽（e）疫苗组合物的疫苗组合物，其包含编码分离的免疫原性HER-2肽的分离的核酸分子; 和（f）使用（1）分离的免疫原性HER-2肽，（2）编码分离的免疫原性HER-2肽的核酸分子来治疗或预防癌症，抑制异常细胞增殖或引起哺乳动物中HER-2蛋白的免疫应答的方法 免疫原性HER-2肽，或（3）包含分离的免疫原性HER-2肽或包含编码分离的免疫原性HER-2肽的核酸分子的组合物的组合物。

    Method of associating timing violations with critical structures in an integrated circuit design
    5.
    发明授权
    Method of associating timing violations with critical structures in an integrated circuit design 失效
    将定时违规与集成电路设计中的关键结构相关联的方法

    公开(公告)号：US07380228B2

    公开(公告)日：2008-05-27

    申请号：US10984115

    申请日：2004-11-08

    申请人： Randall P. Fry ,  Gregory Pierce ,  Juergen Lahner

    发明人： Randall P. Fry ,  Gregory Pierce ,  Juergen Lahner

    IPC分类号： G06F9/45 ,  G06F17/50

    CPC分类号： G06F17/5031

    摘要： A method and computer program product for associating timing violations with critical structures in an integrated circuit design include steps of: (a) receiving as input an integrated circuit design; (b) identifying a critical structure in the integrated circuit design; and (c) generating as output a script for a static timing analysis tool that includes a timing check for a path having a start point at an input of the critical structure and an end point at an output of the critical structure.

    摘要翻译： 一种用于将定时违规与关键结构相关联的集成电路设计的方法和计算机程序产品包括以下步骤：（a）作为输入接收集成电路设计; （b）识别集成电路设计中的关键结构; 以及（c）生成用于静态时序分析工具的输出脚本，该工具包括对关键结构的输入端具有起始点的路径的定时检查以及临界结构输出端的终点。

    Method of associating timing violations with critical structures in an integrated circuit design
    8.
    发明申请
    Method of associating timing violations with critical structures in an integrated circuit design 失效
    将定时违规与集成电路设计中的关键结构相关联的方法

    公开(公告)号：US20060101363A1

    公开(公告)日：2006-05-11

    申请号：US10984115

    申请日：2004-11-08

    申请人： Randall Fry ,  Gregory Pierce ,  Juergen Lahner

    发明人： Randall Fry ,  Gregory Pierce ,  Juergen Lahner

    IPC分类号： G06F17/50 ,  G06F9/45

    CPC分类号： G06F17/5031

    摘要： A method and computer program product for associating timing violations with critical structures in an integrated circuit design include steps of: (a) receiving as input an integrated circuit design; (b) identifying a critical structure in the integrated circuit design; and (c) generating as output a script for a static timing analysis tool that includes a timing check for a path having a start point at an input of the critical structure and an end point at an output of the critical structure.

    摘要翻译： 一种用于将定时违规与关键结构相关联的集成电路设计的方法和计算机程序产品包括以下步骤：（a）作为输入接收集成电路设计; （b）识别集成电路设计中的关键结构; 以及（c）生成用于静态时序分析工具的输出脚本，该工具包括对关键结构的输入端具有起始点的路径的定时检查以及临界结构输出端的终点。