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公开(公告)号：US20070129305A1
公开(公告)日：2007-06-07
申请号：US11294421
申请日：2005-12-06
CPC分类号： C07K14/00
摘要： The present invention concerns cell-penetrating peptides which comprise an amino acid sequence consisting of GLX9WRAX9WRX1LX2RSLX9WX3X4X5X6X7X8 (SEQ ID No: 1), wherein X1 is A, L or G, X2 is W or none, X3 is R or K, X4 is K, L or S, X5 is L or K, X6 is R or W, X7 is K or S, and X8 is A, V or Q, and X9 is W, F or Y. These CPPs can be used as vectors for delivering nucleic acids and/or proteins and/or peptides to cells, in vitro or in vivo.
摘要翻译： 本发明涉及细胞穿透肽，其包含由GLX 9 WRAX 9 WRX 1 LX 2 / SEQ ID NO：1组成的氨基酸序列， 3 （SEQ ID No：1），其中X 1是A，L或G，X 2是 W或不是X 3是R或K，X 4是K，L或S，X 5是L或K，X < S> 6是R或W，X 7是K或S，X 8是A，V或Q，X 9， / SUB>是W，F或Y.这些CPP可用作体外或体内将核酸和/或蛋白质和/或肽递送至细胞的载体。
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公开(公告)号：US20100099626A2
公开(公告)日：2010-04-22
申请号：US12346000
申请日：2008-12-30
CPC分类号： C07K14/00
摘要： The present invention concerns cell-penetrating peptides which comprise an amino acid sequence consisting of GLX9WRAX9WRX1LX2RSLX9WX3X4X5X6X7X8 (SEQ ID No: 1), wherein X1 is A, L or G, X2 is W or none, X3 is R or K, X4 is K, L or S, X5 is L or K, X6 is R or W, X7 is K or S, and X8 is A, V or Q, and X9 is W, F or Y. These CPPs can be used as vectors for delivering nucleic acids and/or proteins and/or peptides to cells, in vitro or in vivo.
摘要翻译： 本发明涉及包含由GLX9WRAX9WRX1LX2RSLX9WX3X4X5X6X7X8（SEQ ID No：1）组成的氨基酸序列的细胞穿透肽，其中X1为A，L或G，X2为W或无，X3为R或K，X4为K， L或S，X 5为L或K，X 6为R或W，X 7为K或S，X 8为A，V或Q，X 9为W，F或Y.这些CPP可用作递送核酸 酸和/或蛋白质和/或肽在体外或体内。
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公开(公告)号：US08242081B2
公开(公告)日：2012-08-14
申请号：US12096378
申请日：2006-12-05
CPC分类号： C07K14/001 , A61K48/00 , C07K7/08 , C12N15/111 , C12N15/113 , C12N2310/14 , C12N2320/32
摘要： The present invention concerns cell-penetrating peptides which comprise an amino acid sequence consisting of GLX9RALX9RX1LX2RSLX9X3X4X5X6X7X8 (SEQ ID No: 1), wherein X1 is A, L or G, X2 is W or none, X3 is R or K, X4 is K, L or S, X5 is L or K, X6 is R or W, X7 is K or S, and X8 is A, V or Q, and X9 is W, F or Y. These CPPs can be used as vectors for delivering nucleic acids and/or proteins and/or peptides to cells, in vitro or in vivo.
摘要翻译： 本发明涉及包含由GLX9RALX9RX1LX2RSLX9X3X4X5X6X7X8（SEQ ID No：1）组成的氨基酸序列的细胞穿透肽，其中X1为A，L或G，X2为W或无，X3为R或K，X4为K， L或S，X 5为L或K，X 6为R或W，X 7为K或S，X 8为A，V或Q，X 9为W，F或Y.这些CPP可用作递送核酸 酸和/或蛋白质和/或肽在体外或体内。
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公开(公告)号：US07943581B2
公开(公告)日：2011-05-17
申请号：US12346000
申请日：2008-12-30
CPC分类号： C07K14/00
摘要： The present invention concerns cell-penetrating peptides which comprise an amino acid sequence consisting of GLX9WRAX9WRX1LX2RSLX9WX3X4X5X6X7X8(SEQ ID No: 1), wherein X1 is A, L or G, X2 is W or none, X3 is R or K, X4 is K, L or S, X5 is L or K, X6 is R or W, X7 is K or S, and X8 is A, V or Q, and X9 is W, F or Y. These CPPs can be used as vectors for delivering nucleic acids and/or proteins and/or peptides to cells, in vitro or in vivo.
摘要翻译： 本发明涉及包含由GLX9WRAX9WRX1LX2RSLX9WX3X4X5X6X7X8（SEQ ID No：1）组成的氨基酸序列的细胞穿透肽，其中X1为A，L或G，X2为W或无，X3为R或K，X4为K， L或S，X 5为L或K，X 6为R或W，X 7为K或S，X 8为A，V或Q，X 9为W，F或Y.这些CPP可用作递送核酸 酸和/或蛋白质和/或肽在体外或体内。
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公开(公告)号：US20090292003A1
公开(公告)日：2009-11-26
申请号：US12096378
申请日：2006-12-05
IPC分类号： A61K31/7088 , C07K14/00 , A61P35/00
CPC分类号： C07K14/001 , A61K48/00 , C07K7/08 , C12N15/111 , C12N15/113 , C12N2310/14 , C12N2320/32
摘要： The present invention concerns cell-penetrating peptides which comprise an amino acid sequence consisting of GLX9RALX9RX1LX2RSLX9X3X4X5X6X7X8 (SEQ ID No: 1), wherein X1 is A, L or G, X2 is W or none, X3 is R or K, X4 is K, L or S, X5 is L or K, X6 is R or W, X7 is K or S, and X8 is A, V or Q, and X9 is W, F or Y. These CPPs can be used as vectors for delivering nucleic acids and/or proteins and/or peptides to cells, in vitro or in vivo.
摘要翻译： 本发明涉及包含由GLX9RALX9RX1LX2RSLX9X3X4X5X6X7X8（SEQ ID No：1）组成的氨基酸序列的细胞穿透肽，其中X1为A，L或G，X2为W或无，X3为R或K，X4为K， L或S，X 5为L或K，X 6为R或W，X 7为K或S，X 8为A，V或Q，X 9为W，F或Y.这些CPP可用作递送核酸 酸和/或蛋白质和/或肽在体外或体内。
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公开(公告)号：US07579318B2
公开(公告)日：2009-08-25
申请号：US11294421
申请日：2005-12-06
IPC分类号： A61K38/00
CPC分类号： C07K14/00
摘要： The present invention concerns cell-penetrating peptides which comprise an amino acid sequence consisting of GLX9WRAX9WRX1LX2RSLX9WX3X4X5X6X7X8 (SEQ ID No: 1), wherein X1 is A, L or G, X2 is W or none, X3 is R or K, X4 is K, L or S, X5 is L or K, X6 is R or W, X7 is K or S, and X8 is A, V or Q, and X9 is W, F or Y. These CPPs can be used as vectors for delivering nucleic acids and/or proteins and/or peptides to cells, in vitro or in vivo.
摘要翻译： 本发明涉及包含由GLX9WRAX9WRX1LX2RSLX9WX3X4X5X6X7X8（SEQ ID No：1）组成的氨基酸序列的细胞穿透肽，其中X1为A，L或G，X2为W或无，X3为R或K，X4为K， L或S，X 5为L或K，X 6为R或W，X 7为K或S，X 8为A，V或Q，X 9为W，F或Y.这些CPP可用作递送核酸 酸和/或蛋白质和/或肽在体外或体内。
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公开(公告)号：US20090156503A1
公开(公告)日：2009-06-18
申请号：US12346000
申请日：2008-12-30
CPC分类号： C07K14/00
摘要： The present invention concerns cell-penetrating peptides which comprise an amino acid sequence consisting of GLX9WRAX9WRX1LX2RSLX9WX3X4X5X6X7X8(SEQ ID No: 1), wherein X1 is A, L or G, X2 is W or none, X3 is R or K, X4 is K, L or S, X5 is L or K, X6 is R or W, X7 is K or S, and X8 is A, V or Q, and X9 is W, F or Y. These CPPs can be used as vectors for delivering nucleic acids and/or proteins and/or peptides to cells, in vitro or in vivo.
摘要翻译： 本发明涉及包含由GLX9WRAX9WRX1LX2RSLX9WX3X4X5X6X7X8（SEQ ID No：1）组成的氨基酸序列的细胞穿透肽，其中X1为A，L或G，X2为W或无，X3为R或K，X4为K， L或S，X 5为L或K，X 6为R或W，X 7为K或S，X 8为A，V或Q，X 9为W，F或Y.这些CPP可用作递送核酸 酸和/或蛋白质和/或肽在体外或体内。
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