专利检索 ap:("Pedro Cuevas Sánchez" OR "Guillermo Gimenez Gallego" OR "Inigo Saenz de Tejada Gorgan" OR "Javier Angulo Frutos" OR "Serafin Valverde Lopez" OR "Antonio Romero Garrido" OR "Rosa Maria Lozano Puerto") AND inv:"Javier Angulo Frutos" 第 1 页

1.

发明申请
USE OF 2,5-DIHYDROXYBENZENE DERIVATIVES FOR TREATING DERMATITIS 有权
标题翻译：使用2,5-二羟基苯衍生物进行处理

公开(公告)号：US20120087947A1

公开(公告)日：2012-04-12

申请号：US13209803

申请日：2011-08-15

申请人： Pedro Cuevas Sánchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Gorgan , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto

发明人： Pedro Cuevas Sánchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Gorgan , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto

IPC分类号： A61K31/255 , A61K31/192 , A61K38/46 , A61K31/675 , A61K31/56 , A61K31/436 , A61K31/606 , A61P17/00 , A61P31/00 , A61P29/00 , A61P37/02 , A61P37/06 , A61P23/00 , A61P35/00 , A61K31/235

CPC分类号： A61K31/185 , A61K8/368 , A61K8/466 , A61K31/10 , A61K31/192 , A61K31/222 , A61K31/225 , A61K31/60 , A61K31/618 , A61K45/06 , A61Q17/04 , A61Q19/08

摘要： The present invention relates to the use of a 2,5-dihydroxybenzene derivative represented by Formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the therapeutic and/or prophylactic treatment of, inter alia, dermatitis.

摘要翻译： 本发明涉及由式（I）表示的2,5-二羟基苯衍生物或其药学上可接受的盐，溶剂合物，异构体或前药用于治疗和/或预防性治疗特别是皮炎的用途。

2.

发明授权
Use of 2,5-dihydroxybenzene derivatives for the treatment of arthritis and pain 有权
标题翻译：使用2,5-二羟基苯衍生物治疗关节炎和疼痛

公开(公告)号：US09060966B2

公开(公告)日：2015-06-23

申请号：US12377837

申请日：2007-08-15

申请人： Pedro Cuevas Sánchez , Guillermo Gimenez Gallego , Javier Angulo Frutos , Rosa Maria Lozano Puerto , Antonio Romero Garrido , Serafin Valverde Lopez , Maria Luisa Krauel

发明人： Pedro Cuevas Sánchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Morgan , Javier Angulo Frutos , Rosa Maria Lozano Puerto , Antonio Romero Garrido , Serafin Valverde Lopez

IPC分类号： A61K31/045 , A61K31/15 , A61K31/10 , A61K31/192 , A61K31/60 , A61K31/618

CPC分类号： A61K31/10 , A61K31/192 , A61K31/60 , A61K31/618 , Y02A50/409

摘要： The present invention relates to the use of a compound of Formula (I′″) or pharmaceutically acceptable salt or solvate, isomer or prodrug thereof in the manufacturing of a medicament for the treatment and/or prophylaxis of arthritis and pain.

摘要翻译： 本发明涉及式（I'“）化合物或其药学上可接受的盐或溶剂合物，异构体或前药在制备用于治疗和/或预防关节炎和疼痛的药物中的用途。

3.

发明授权
Use of 2,5-dihydroxybenzene compounds and derivatives for the treatment of rosacea 有权

公开(公告)号：US08492367B2

公开(公告)日：2013-07-23

申请号：US13154164

申请日：2011-06-06

申请人： Pedro Cuevas Sánchez , Guillermo Gimenez Gallego , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto

发明人： Pedro Cuevas Sánchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Gorman , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto

IPC分类号： A01N37/36 , A01N45/00 , A01N41/02 , A01N37/10 , A01N37/02 , A61K31/56 , A61K31/255 , A61K31/235 , A61K31/22 , A61K37/19

CPC分类号： A61K31/255 , A61K9/0014 , A61K31/095 , A61K31/10 , A61K31/185 , A61K31/192 , A61K31/216 , A61K31/222 , A61K31/225 , A61K31/235 , A61K45/06 , C07C57/44 , C07C59/68 , C07C65/03 , C07C65/19 , C07C69/017 , C07C69/84 , C07C309/24 , C07C309/42 , C07C309/68 , C07C309/75 , A61K2300/00

摘要： The present invention relates to the use of a 2,5-dihydroxybenzene derivative of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the treatment and/or prophylaxis of, inter alia, rosacea.

4.

发明授权
Use of 2,5-dihydroxybenzene for the treatment of ocular diseases 有权
标题翻译：使用2,5-二羟基苯治疗眼部疾病

公开(公告)号：US09198886B2

公开(公告)日：2015-12-01

申请号：US12986674

申请日：2011-01-07

申请人： Pedro Cuevas Sánchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Morgan , Maria Luisa Krauel , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto

发明人： Pedro Cuevas Sánchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Morgan , Javier Angulo Frutos , Serafin Valverde Lopez , Antonio Romero Garrido , Rosa Maria Lozano Puerto

IPC分类号： A61K31/185 , A61K31/192 , A61K31/235 , A61K31/56 , A61K45/06

CPC分类号： A61K31/185 , A61K31/192 , A61K31/235 , A61K31/56 , A61K45/06

摘要： The present invention relates to the use of a compound of Formula (IIV) or pharmaceutically acceptable salt or solvate, isomer or prodrug thereof in the manufacturing of a medicament for the treatment and/or prophylaxis of any of the diseases selected from the group consisting of macular degeneration, corneal neovascularization or angiogenesis, iris neovascularization or angiogenesis, retinal neovascularization or angiogenesis, diabetic proliferative retinopathy and non-diabetic proliferative retinopathy.

摘要翻译： 本发明涉及式（IIV）化合物或其药学上可接受的盐或溶剂化物，异构体或前体药物在制备用于治疗和/或预防任何选自下组的疾病的药物中的用途：黄斑变性，角膜新生血管形成或血管生成，虹膜新生血管形成或血管生成，视网膜新生血管形成或血管生成，糖尿病性增生性视网膜病变和非糖尿病性增生性视网膜病变。

5.

发明授权
Use of 2,5-dihydroxybenzene compounds and derivatives for the treatment of hematological dyscrasias and cancer of an organ 有权
标题翻译： 2,5-二羟基苯化合物及其衍生物用于治疗器官的血液恶化和癌症

公开(公告)号：US08541467B2

公开(公告)日：2013-09-24

申请号：US11839525

申请日：2007-08-15

申请人： Pedro Cuevas Sánchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Morgan , Javier Angulo Frutos , Rosa Maria Lozano Puerto , Antonio Romero Garrido , Serafin Valverde Lopez

发明人： Pedro Cuevas Sánchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Morgan , Javier Angulo Frutos , Rosa Maria Lozano Puerto , Antonio Romero Garrido , Serafin Valverde Lopez

IPC分类号： A01N37/02 , A01N41/10 , A01N31/08 , A61K31/22 , A61K31/225

CPC分类号： A61K31/255 , A61K9/0014 , A61K31/095 , A61K31/10 , A61K31/185 , A61K31/192 , A61K31/216 , A61K31/222 , A61K31/225 , A61K31/235 , A61K45/06 , C07C57/44 , C07C59/68 , C07C65/03 , C07C65/19 , C07C69/017 , C07C69/84 , C07C309/24 , C07C309/42 , C07C309/68 , C07C309/75 , A61K2300/00

摘要： The present invention refers to the use of the compound of Formula (I′) or pharmaceutically acceptable salt, solvate, isomer, or prodrug thereof for the treatment and/or prophylaxis of hematological dyscrasias, including myelodisplastic syndromes (MDSs) and for improving the efficacy of chemotherapy, radiation therapy and/or cancer immunotherapy. In addition, it relates to the use of a compound of formula (I″) for the treatment and/or prophylaxis of cancer of an organ.

摘要翻译： 本发明涉及式（I'）化合物或其药学上可接受的盐，溶剂合物，异构体或前体药物在治疗和/或预防血液恶化症中的用途，包括骨髓增生异常综合征（MDS）和用于改善功效的化疗，放射治疗和/或癌症免疫治疗。此外，它涉及式（I“）化合物用于治疗和/或预防器官癌症的用途。

6.

发明申请
USE OF 2,5-DIHYDROXYBENZENE FOR THE TREATMENT OF OCULAR DISEASES 审中-公开
标题翻译：使用2,5-二羟基苯甲醚治疗眼部疾病

公开(公告)号：US20120015912A1

公开(公告)日：2012-01-19

申请号：US12986674

申请日：2011-01-07

申请人： Pedro Cuevas Sánchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Morgan , Maria Luisa Krauel , Javier Angulo Frutos , Rosa Maria Lozano Puerto , Antonio Romero Garrido , Serafin Valverde Lopez

发明人： Pedro Cuevas Sánchez , Guillermo Gimenez Gallego , Inigo Saenz de Tejada Morgan , Maria Luisa Krauel , Javier Angulo Frutos , Rosa Maria Lozano Puerto , Antonio Romero Garrido , Serafin Valverde Lopez

IPC分类号： A61K31/185 , C07C65/05 , A61K31/235 , A61K31/192 , A61K31/56 , A61P31/00 , A61P37/02 , A61P37/06 , A61P35/00 , A61P29/00 , A61P39/06 , A61P33/00 , A61P23/00 , A61P27/02 , C07C309/42

CPC分类号： A61K31/185 , A61K31/192 , A61K31/235 , A61K31/56 , A61K45/06

摘要： The present invention relates to the use of a compound of Formula (IIV) or pharmaceutically acceptable salt or solvate, isomer or prodrug thereof in the manufacturing of a medicament for the treatment and/or prophylaxis of any of the diseases selected from the group consisting of macular degeneration, corneal neovascularization or angiogenesis, iris neovascularization or angiogenesis, retinal neovascularization or angiogenesis, diabetic proliferative retinopathy and non-diabetic proliferative retinopathy.

摘要翻译： 本发明涉及式（IIV）化合物或其药学上可接受的盐或溶剂化物，异构体或前体药物在制备用于治疗和/或预防任何选自下组的疾病的药物中的用途：黄斑变性，角膜新生血管形成或血管生成，虹膜新生血管形成或血管生成，视网膜新生血管形成或血管生成，糖尿病性增生性视网膜病变和非糖尿病性增生性视网膜病变。