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1.发明申请公开(公告)号：US20050026926A1
公开(公告)日：2005-02-03
申请号：US10866101
申请日：2004-06-14
Applicant: Heinz Uragg , Corinne Maul , Helmut Buschmann , Bernd Sundermann , Hagen-Heinrich Hennies
Inventor： Heinz Uragg , Corinne Maul , Helmut Buschmann , Bernd Sundermann , Hagen-Heinrich Hennies
IPC: C07D295/08 , A61K31/495 , A61K31/496 , A61P1/08 , A61P1/12 , A61P9/00 , A61P9/06 , A61P13/00 , A61P15/00 , A61P17/04 , A61P23/02 , A61P25/04 , A61P25/18 , A61P25/20 , A61P25/24 , A61P25/30 , A61P25/32 , A61P29/00 , C07D295/088 , C07D295/096 , C07D333/20
CPC classification number: C07D295/096 , C07D295/088
Abstract: N,N′-disubstituted piperazine compounds, processes for the production thereof, and pharmaceutical preparations containing these compounds. The use of N,N′-disubstituted piperazine compounds for the production of pharmaceutical preparations and in related methods of treatment.
Abstract translation: N，N'-二取代哌嗪化合物，其制备方法和含有这些化合物的药物制剂。 使用N，N'-二取代的哌嗪化合物用于制备药物制剂和相关的治疗方法。
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公开(公告)号：US20050020691A1
公开(公告)日：2005-01-27
申请号：US10866099
申请日：2004-06-14
Applicant: Heinz Uragg , Corinna Maul , Helmut Buschmann , Bernd Sundermann , Hagen-Heinrich Hennies
Inventor： Heinz Uragg , Corinna Maul , Helmut Buschmann , Bernd Sundermann , Hagen-Heinrich Hennies
IPC: C07D295/08 , A61K31/40 , A61K31/445 , A61K31/535 , A61K31/55 , A61P1/08 , A61P1/12 , A61P9/00 , A61P13/00 , A61P15/10 , A61P17/04 , A61P25/00 , A61P25/04 , A61P25/24 , A61P25/26 , A61P25/28 , A61P25/30 , A61P25/32 , A61P29/00 , C07D295/096 , A61K31/137
CPC classification number: C07D295/096 , A61K31/40 , A61K31/445 , A61K31/535 , A61K31/55
Abstract: Pharmaceutical compositions containing substituted aminoalcohols, the use of preparations containing substituted aminoalcohols for treatment of conditions such as pain, emesis, neurotropic conditions, cardiovascular diseases, urinary incontinence, diarrhea, pruritus, alcohol or drug dependency, inflammation, depression, decreased vigilance, or depressed libido, as well as 2-(aminomethyl)cycloalkane-1-ol compounds and a process for their preparation.
Abstract translation: 含有取代氨基醇的药物组合物，含有取代氨基醇的制剂用于治疗诸如疼痛，呕吐，神经营养状况，心血管疾病，尿失禁，腹泻，瘙痒，酒精或药物依赖性，炎症，抑郁，降低的警惕性或抑郁症 性状，以及2-（氨基甲基）环烷烃-1-醇化合物及其制备方法。
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公开(公告)号：US07569585B2
公开(公告)日：2009-08-04
申请号：US10866088
申请日：2004-06-14
Applicant: Heinz Uragg , Corinna Maul , Helmut Buschmann , Bernd Sundermann , Werner Englberger
Inventor： Heinz Uragg , Corinna Maul , Helmut Buschmann , Bernd Sundermann , Werner Englberger
IPC: A61K31/445 , C07D401/06
CPC classification number: A61K31/133 , A61K31/44 , C07D295/088 , C07D333/16
Abstract: Substituted 1,5-diaminopentan-3-ol compounds and methods of making the same. Pharmaceutical compositions containing these compounds and methods of treatment using these pharmaceutical compositions.
Abstract translation: 取代的1,5-二氨基戊烷-3-醇化合物及其制备方法。 含有这些化合物的药物组合物和使用这些药物组合物的治疗方法。
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公开(公告)号：US07507816B2
公开(公告)日：2009-03-24
申请号：US10866099
申请日：2004-06-14
Applicant: Heinz Uragg , Corinna Maul , Helmut Buschmann , Bernd Sundermann , Hagen-Heinrich Hennies
Inventor： Heinz Uragg , Corinna Maul , Helmut Buschmann , Bernd Sundermann , Hagen-Heinrich Hennies
IPC: C07D267/02 , C07D267/04 , C07D267/06 , C07D267/08 , C07D267/10 , C07D281/02 , C07D281/04 , C07D281/06
CPC classification number: C07D295/096 , A61K31/40 , A61K31/445 , A61K31/535 , A61K31/55
Abstract: Pharmaceutical compositions containing substituted aminoalcohols, the use of preparations containing substituted aminoalcohols for treatment of conditions such as pain, emesis, neurotropic conditions, cardiovascular diseases, urinary incontinence, diarrhea, pruritus, alcohol or drug dependency, inflammation, depression, decreased vigilance, or depressed libido, as well as 2-(aminomethyl)cycloalkane-1-ol compounds and a process for their preparation.
Abstract translation: 含有取代氨基醇的药物组合物，含有取代氨基醇的制剂用于治疗诸如疼痛，呕吐，神经营养状况，心血管疾病，尿失禁，腹泻，瘙痒，酒精或药物依赖性，炎症，抑郁，降低的警惕性或抑郁症 性状，以及2-（氨基甲基）环烷烃-1-醇化合物及其制备方法。
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5.发明授权Pharmaceutical formulations comprising N,N′-disubstituted piperazine compounds 有权包含N，N'-二取代哌嗪化合物的药物制剂公开(公告)号：US07816358B2
公开(公告)日：2010-10-19
申请号：US10866100
申请日：2004-06-14
Applicant: Heinz Uragg , Corinna Maul , Helmut Buschmann , Bernd Sundermann , Michael Haubrand , Boris Chizh
Inventor： Heinz Uragg , Corinna Maul , Helmut Buschmann , Bernd Sundermann , Michael Haubrand , Boris Chizh
IPC: A61K31/497 , C07D241/04
CPC classification number: A61K31/496 , A61K31/495
Abstract: Pharmaceutical formulations comprising N,N′disubstituted piperazine compounds and related methods of treatment using these formulations.
Abstract translation: 包含N，N'-二取代哌嗪化合物的药物制剂和使用这些制剂的相关治疗方法。
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Patent Agency Ranking
6.发明授权公开(公告)号：US07390812B2
公开(公告)日：2008-06-24
申请号：US10866101
申请日：2004-06-14
Applicant: Heinz Uragg , Corinne Maul , Helmut Buschmann , Bernd Sundermann , Hagen-Heinrich Hennies
Inventor： Heinz Uragg , Corinne Maul , Helmut Buschmann , Bernd Sundermann , Hagen-Heinrich Hennies
IPC: A61K31/497
CPC classification number: C07D295/096 , C07D295/088
Abstract: N,N′-disubstituted piperazine compounds, processes for the production thereof, and pharmaceutical preparations containing these compounds. The use of N,N′-disubstituted piperazine compounds for the production of pharmaceutical preparations and in related methods of treatment.
Abstract translation: N，N'-二取代哌嗪化合物，其制备方法和含有这些化合物的药物制剂。 使用N，N'-二取代的哌嗪化合物用于制备药物制剂和相关的治疗方法。
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公开(公告)号：US20080085900A1
公开(公告)日：2008-04-10
申请号：US11742946
申请日：2007-05-01
Applicant: MATTHIAS GERLACH , Heinz Uragg , Michael Haurand , Claudia Puetz , Corinna Sundermann , Boris Chizh
Inventor： MATTHIAS GERLACH , Heinz Uragg , Michael Haurand , Claudia Puetz , Corinna Sundermann , Boris Chizh
IPC: A61K31/18 , A61K31/341 , A61K31/381 , A61K31/40 , A61K31/415 , A61K31/4402 , A61K31/4458 , A61K31/495 , A61K31/505 , A61K31/5375 , A61P25/00 , C07C311/18 , C07D207/16 , C07D213/58 , C07D213/72 , C07D231/38 , C07D239/26 , C07D295/12 , C07D295/28 , C07D307/52 , C07D333/22
CPC classification number: C07D213/40 , C07C311/49 , C07C311/64 , C07C2601/14 , C07D213/75 , C07D213/77 , C07D231/40 , C07D239/26 , C07D295/215 , C07D295/32 , C07D307/52 , C07D333/20 , C07D401/12 , C07D409/12 , C07D521/00
Abstract: Sulfonylguanidine compounds corresponding to the tautomeric formulas I and Ia, a method for producing them, pharmaceutical compositions containing them, and methods of using them to prepare medicaments and for treating various medical conditions. The sulfonylguanidine compounds have an affinity for the gabapentin binding site and can be used to treat conditions such as pain, epilepsy, migraine and others.
Abstract translation: 对应于互变异构体式I和Ia的磺酰胍化合物，其制备方法，含有它们的药物组合物及其用于制备药物和用于治疗各种医疗条件的方法。 磺酰胍类化合物对加巴喷丁结合位点具有亲和力，可用于治疗疼痛，癫痫，偏头痛等疾病。
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公开(公告)号：US07671074B2
公开(公告)日：2010-03-02
申请号：US11742946
申请日：2007-05-01
Applicant: Matthias Gerlach , Heinz Uragg , Michael Haurand , Claudia Katharina Puetz , Corinna Sundermann , Boris Chizh
Inventor： Matthias Gerlach , Heinz Uragg , Michael Haurand , Claudia Katharina Puetz , Corinna Sundermann , Boris Chizh
IPC: A61K31/44
CPC classification number: C07D213/40 , C07C311/49 , C07C311/64 , C07C2601/14 , C07D213/75 , C07D213/77 , C07D231/40 , C07D239/26 , C07D295/215 , C07D295/32 , C07D307/52 , C07D333/20 , C07D401/12 , C07D409/12 , C07D521/00
Abstract: Sulfonylguanidine compounds corresponding to the tautomeric formulas I and Ia, a method for producing them, pharmaceutical compositions containing them, and methods of using them to prepare medicaments and for treating various medical conditions. The sulfonylguanidine compounds have an affinity for the gabapentin binding site and can be used to treat conditions such as pain, epilepsy, migraine and others.
Abstract translation: 对应于互变异构体式I和Ia的磺酰胍化合物，其制备方法，含有它们的药物组合物及其用于制备药物和用于治疗各种医疗条件的方法。 磺酰胍类化合物对加巴喷丁结合位点具有亲和力，可用于治疗疼痛，癫痫，偏头痛等疾病。
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9.发明申请Pharmaceutical formulations comprising N,N'-disubstituted piperazine compounds 有权包含N，N'-二取代哌嗪化合物的药物制剂公开(公告)号：US20050038034A1
公开(公告)日：2005-02-17
申请号：US10866100
申请日：2004-06-14
Applicant: Heinz Uragg , Corinna Maul , Helmut Buschmann , Bernd Sundermann , Michael Haurand , Boris Chizh
Inventor： Heinz Uragg , Corinna Maul , Helmut Buschmann , Bernd Sundermann , Michael Haurand , Boris Chizh
IPC: C07D295/08 , A61K31/495 , A61K31/496 , A61P1/00 , A61P1/04 , A61P15/12 , A61P17/00 , A61P19/02 , A61P21/00 , A61P21/02 , A61P21/04 , A61P25/00 , A61P25/02 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P27/02 , A61P29/00
CPC classification number: A61K31/496 , A61K31/495
Abstract: Pharmaceutical formulations comprising N,N′disubstituted piperazine compounds and related methods of treatment using these formulations.
Abstract translation: 包含N，N'-二取代哌嗪化合物的药物制剂和使用这些制剂的相关治疗方法。
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公开(公告)号：US20050020562A1
公开(公告)日：2005-01-27
申请号：US10866088
申请日：2004-06-14
Applicant: Heinz Uragg , Corinna Maul , Helmut Buschmann , Bernd Sundermann , Werner Englberger
Inventor： Heinz Uragg , Corinna Maul , Helmut Buschmann , Bernd Sundermann , Werner Englberger
IPC: C07D295/08 , A61K31/133 , A61K31/135 , A61K31/397 , A61K31/40 , A61K31/44 , A61K31/4402 , A61K31/445 , A61K31/4453 , A61P1/04 , A61P1/08 , A61P1/12 , A61P3/04 , A61P7/00 , A61P7/10 , A61P9/02 , A61P9/06 , A61P9/10 , A61P11/06 , A61P13/10 , A61P15/10 , A61P17/04 , A61P23/00 , A61P23/02 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/26 , A61P25/28 , A61P25/30 , A61P25/32 , A61P25/36 , A61P27/06 , A61P27/16 , A61P29/00 , A61P37/08 , C07B61/00 , C07C213/00 , C07C215/06 , C07C215/18 , C07C215/20 , C07C215/30 , C07C215/42 , C07D207/46 , C07D211/08 , C07D211/26
CPC classification number: A61K31/133 , A61K31/44 , C07D295/088 , C07D333/16
Abstract: Substituted 1,5-diaminopentan-3-ol compounds and methods of making the same. Pharmaceutical compositions containing these compounds and methods of treatment using these pharmaceutical compositions.
Abstract translation: 取代的1,5-二氨基戊烷-3-醇化合物及其制备方法。 含有这些化合物的药物组合物和使用这些药物组合物的治疗方法。
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