公开(公告)号：US06560583B1

公开(公告)日：2003-05-06

申请号：US09372173

申请日：1999-08-11

申请人： Henry Markram

发明人： Henry Markram

IPC分类号： G06N302

CPC分类号： G06N3/049

摘要： A process and apparatus that enable continual self-adaptation of dynamic transmission devices (saSTDs), allow “smart” filtering of information for transmission from one element to another within a network of interacting elements, such as a “neural network”. An adaptation algorithm (MapSA) incorporated in STDs allows multiple parameters of STDs (which determine its filtering properties) to continuously adapt simultaneously and interdependently. In this manner, complex correlations can be established between the parameters in all STDs within a network of interacting elements. The process according to the invention therefore establishes unique patterns of connection parameters within the network which in turn dictates a novel sequence of information processing steps by the network.

摘要翻译： 允许动态传输设备（saSTD）的连续自适应的过程和设备允许在诸如“神经网络”的交互元件的网络内的信息对从一个元件到另一个元件的传输的“智能”过滤。 结合在STD中的自适应算法（MapSA）允许STD的多个参数（确定其过滤属性）能够连续适应并相互依赖。 以这种方式，可以在相互作用的元件的网络内的所有STD中的参数之间建立复杂的相关性。 因此，根据本发明的方法建立了网络内的连接参数的独特模式，这进而决定了网络的新颖的信息处理步骤序列。

公开(公告)号：US20120313798A1

公开(公告)日：2012-12-13

申请号：US13555518

申请日：2012-07-23

申请人： Henry Markram

发明人： Henry Markram

IPC分类号： H03M7/00

CPC分类号： H04L25/493

摘要： Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for encoding and decoding information. In one aspect, methods of encoding information in an encoder include receiving a signal representing information using a collection of discrete digits, converting, by an encoder, the received signal into a time-based code, and outputting the time-based code. The time-based code is divided into time intervals. Each of the time intervals of the time-based code corresponds to a digit in the received signal. Each digit of a first state of the received signal is expressed as an event occurring at a first time within the corresponding time interval of the time-based code. Each digit of a second state of the received signal is expressed as an event occurring at a second time within the corresponding time intervals of the time-based code, the first time is distinguishable from the second time.

摘要翻译： 方法，系统和装置，包括在计算机存储介质上编码的计算机程序，用于对信息进行编码和解码。 在一个方面，编码器中信息编码的方法包括使用离散数字的集合来接收表示信息的信号，由编码器将接收到的信号转换成基于时间的代码，并输出基于时间的代码。 基于时间的代码被分为时间间隔。 基于时间的代码的每个时间间隔对应于接收信号中的数字。 接收信号的第一状态的每个数字表示为在时间码的对应时间间隔内的第一时间发生的事件。 接收信号的第二状态的每个数字被表示为在时间码的对应时间间隔内的第二时间发生的事件，第一次与第二次可区分。

公开(公告)号：US20120119926A1

公开(公告)日：2012-05-17

申请号：US13353760

申请日：2012-01-19

申请人： Henry Markram

发明人： Henry Markram

IPC分类号： H03M7/00

CPC分类号： H04L25/493

摘要： Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for encoding and decoding information. In one aspect, methods of encoding information in an encoder include the actions of receiving a signal representing information using a collection of discrete digits, converting, by an encoder, the received signal into a time-based code, and outputting the time-based code. The time-based code is divided into time intervals. Each of the time intervals of the time-based code corresponds to a digit in the received signal. Each digit of a first state of the received signal is expressed as a event occurring at a first time within the corresponding time interval of the time-based code. Each digit of a second state of the received signal is expressed as a event occurring at a second time within the corresponding time intervals of the time-based code, the first time is distinguishable from the second time. All of the states of the digits in the received signal are represented by events in the time-based code.

摘要翻译： 方法，系统和装置，包括在计算机存储介质上编码的计算机程序，用于对信息进行编码和解码。 一方面，在编码器中编码信息的方法包括使用离散数字集合接收表示信息的信号的动作，由编码器将接收到的信号转换为基于时间的码，并输出基于时间的码 。 基于时间的代码被分为时间间隔。 基于时间的代码的每个时间间隔对应于接收信号中的数字。 接收信号的第一状态的每个数字表示为在时间码的对应时间间隔内的第一时间发生的事件。 接收信号的第二状态的每个数字被表示为在时间码的对应时间间隔内的第二时间发生的事件，第一次与第二次可区分。 接收信号中的数字的所有状态由基于时间的代码中的事件表示。

公开(公告)号：US20110025532A1

公开(公告)日：2011-02-03

申请号：US12844112

申请日：2010-07-27

申请人： Henry Markram

发明人： Henry Markram

IPC分类号： H03M7/14

CPC分类号： H04L25/493

摘要： Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for encoding and decoding information. In one aspect, methods of encoding information in an encoder include the actions of receiving a signal representing information using a collection of discrete digits, converting, by an encoder, the received signal into a time-based code, and outputting the time-based code. The time-based code is divided into time intervals. Each of the time intervals of the time-based code corresponds to a digit in the received signal. Each digit of a first state of the received signal is expressed as a event occurring at a first time within the corresponding time interval of the time-based code. Each digit of a second state of the received signal is expressed as a event occurring at a second time within the corresponding time intervals of the time-based code, the first time is distinguishable from the second time. All of the states of the digits in the received signal are represented by events in the time-based code.

摘要翻译： 方法，系统和装置，包括在计算机存储介质上编码的计算机程序，用于对信息进行编码和解码。 一方面，在编码器中编码信息的方法包括使用离散数字的集合接收表示信息的信号的动作，由编码器将接收到的信号转换为基于时间的代码，并输出基于时间的代码 。 基于时间的代码被分为时间间隔。 基于时间的代码的每个时间间隔对应于接收信号中的数字。 接收信号的第一状态的每个数字表示为在时间码的对应时间间隔内的第一时间发生的事件。 接收信号的第二状态的每个数字被表示为在时间码的对应时间间隔内的第二时间发生的事件，第一次与第二次可区分。 接收信号中的数字的所有状态由基于时间的代码中的事件表示。

公开(公告)号：US20090204469A1

公开(公告)日：2009-08-13

申请号：US12302722

申请日：2007-05-30

申请人： Henry Markram

发明人： Henry Markram

IPC分类号： G06Q99/00 ,  G06Q10/00 ,  G06F17/30 ,  G06Q50/00

CPC分类号： G06Q10/10 ,  G06F16/38 ,  G06Q30/02 ,  G06Q50/205

摘要： A technical method for evaluation, publication and distillation of information, such as scientific articles and other similar work, said method, process and system comprising at least the following technical process steps (1) an interactive online reviewing process of said information before it is published; (2) a publication process of said information if accepted; (3) an evaluation process of said information once published; (4) a distillation process of said published information in a tier filtering system based on said evaluation process.

摘要翻译： 所述方法，过程和系统至少包括以下技术流程步骤（1）在所述信息发布之前的所述信息的互动在线审查过程的技术方法，用于评估，发布和蒸馏诸如科学文章和其他类似工作的信息的技术方法 ; （2）如果接受了所述信息的公布过程; （3）一旦公布的信息的评估过程; （4）基于所述评估过程的层过滤系统中的所述已发布信息的蒸馏处理。

公开(公告)号：US20130109048A1

公开(公告)日：2013-05-02

申请号：US13809315

申请日：2011-07-11

申请人： Michele Giugliano ,  Ruth Luthi-Carter ,  Henry Markram ,  Luca Gambazzi ,  Ozgün Gökce

发明人： Michele Giugliano ,  Ruth Luthi-Carter ,  Henry Markram ,  Luca Gambazzi ,  Ozgün Gökce

IPC分类号： C12Q1/02

CPC分类号： C12Q1/025 ,  G01N33/4836 ,  G01N33/5058

摘要： The present invention relates to methods and neuronal cellular preparations allowing monitoring intracellular and transcellular molecular events on both short and long timescales in an ex vivo neuronal network of intact post-mitotic neurons. In particular, the invention relates to methods, kits, genetically engineered neuronal cells, preparations and uses thereof allowing the ex vivo monitoring of early neuronal disease-related changes in neuronal network behavior.

摘要翻译： 本发明涉及允许在完整的后有丝分裂神经元的离体神经元网络中在短时间和长时间尺度上监测细胞内和跨细胞分子事件的方法和神经元细胞制剂。 特别地，本发明涉及方法，试剂盒，遗传工程神经元细胞，其制备方法及其用途，其允许离体监测神经元网络行为的早期神经元疾病相关变化。

公开(公告)号：US20120323833A1

公开(公告)日：2012-12-20

申请号：US13566128

申请日：2012-08-03

申请人： Henry Markram ,  Rodrigo de Campos Perin ,  Thomas K. Berger

发明人： Henry Markram ,  Rodrigo de Campos Perin ,  Thomas K. Berger

IPC分类号： G06N3/04

CPC分类号： G06N3/0454 ,  G06N3/08 ,  G06N3/082

摘要： Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for organizing trained and untrained neural networks. In one aspect, a neural network device includes a collection of node assemblies interconnected by between-assembly links, each node assembly itself comprising a network of nodes interconnected by a plurality of within-assembly links, wherein each of the between-assembly links and the within-assembly links have an associated weight, each weight embodying a strength of connection between the nodes joined by the associated link, the nodes within each assembly being more likely to be connected to other nodes within that assembly than to be connected to nodes within others of the node assemblies.

摘要翻译： 方法，系统和装置，包括在计算机存储介质上编码的计算机程序，用于组织训练和未经训练的神经网络。 在一个方面，神经网络设备包括通过组件间链路相互连接的节点组合的集合，每个节点组件本身包括通过多个内部组件链接互连的节点网络，其中每个组件间链接和 组装内链接具有相关联的权重，每个权重体现由相关联的链接连接的节点之间的连接强度，每个组件内的节点更可能连接到该组件内的其他节点而不是连接到其他节点内的节点 的节点组件。

公开(公告)号：US08253607B2

公开(公告)日：2012-08-28

申请号：US13353760

申请日：2012-01-19

申请人： Henry Markram

发明人： Henry Markram

IPC分类号： H03M7/00

CPC分类号： H04L25/493

摘要： Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for encoding and decoding information. In one aspect, methods of encoding information in an encoder include the actions of receiving a signal representing information using a collection of discrete digits, converting, by an encoder, the received signal into a time-based code, and outputting the time-based code. The time-based code is divided into time intervals. Each of the time intervals of the time-based code corresponds to a digit in the received signal. Each digit of a first state of the received signal is expressed as a event occurring at a first time within the corresponding time interval of the time-based code. Each digit of a second state of the received signal is expressed as a event occurring at a second time within the corresponding time intervals of the time-based code, the first time is distinguishable from the second time. All of the states of the digits in the received signal are represented by events in the time-based code.

摘要翻译： 方法，系统和装置，包括在计算机存储介质上编码的计算机程序，用于对信息进行编码和解码。 一方面，在编码器中编码信息的方法包括使用离散数字集合接收表示信息的信号的动作，由编码器将接收到的信号转换为基于时间的码，并输出基于时间的码 。 基于时间的代码被分为时间间隔。 基于时间的代码的每个时间间隔对应于接收信号中的数字。 接收信号的第一状态的每个数字表示为在时间码的对应时间间隔内的第一时间发生的事件。 接收信号的第二状态的每个数字被表示为在时间码的对应时间间隔内的第二时间发生的事件，第一次与第二次可区分。 接收信号中的数字的所有状态由基于时间的代码中的事件表示。

公开(公告)号：US10387767B2

公开(公告)日：2019-08-20

申请号：US13566128

申请日：2012-08-03

申请人： Henry Markram ,  Rodrigo de Campos Perin ,  Thomas K. Berger

发明人： Henry Markram ,  Rodrigo de Campos Perin ,  Thomas K. Berger

IPC分类号： G06N3/04 ,  G06F3/08 ,  G06N3/08

摘要： Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for organizing trained and untrained neural networks. In one aspect, a neural network device includes a collection of node assemblies interconnected by between-assembly links, each node assembly itself comprising a network of nodes interconnected by a plurality of within-assembly links, wherein each of the between-assembly links and the within-assembly links have an associated weight, each weight embodying a strength of connection between the nodes joined by the associated link, the nodes within each assembly being more likely to be connected to other nodes within that assembly than to be connected to nodes within others of the node assemblies.

公开(公告)号：US08941512B2

公开(公告)日：2015-01-27

申请号：US13555518

申请日：2012-07-23

申请人： Henry Markram

发明人： Henry Markram

IPC分类号： H03M7/00 ,  H04L25/493

CPC分类号： H04L25/493

摘要： Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for encoding and decoding information. In one aspect, methods of encoding information in an encoder include receiving a signal representing information using a collection of discrete digits, converting, by an encoder, the received signal into a time-based code, and outputting the time-based code. The time-based code is divided into time intervals. Each of the time intervals of the time-based code corresponds to a digit in the received signal. Each digit of a first state of the received signal is expressed as an event occurring at a first time within the corresponding time interval of the time-based code. Each digit of a second state of the received signal is expressed as an event occurring at a second time within the corresponding time intervals of the time-based code, the first time is distinguishable from the second time.

摘要翻译： 方法，系统和装置，包括在计算机存储介质上编码的计算机程序，用于对信息进行编码和解码。 在一个方面，编码器中信息编码的方法包括使用离散数字的集合接收表示信息的信号，由编码器将接收到的信号转换成基于时间的代码，并输出基于时间的代码。 基于时间的代码被分为时间间隔。 基于时间的代码的每个时间间隔对应于接收信号中的数字。 接收信号的第一状态的每个数字表示为在时间码的对应时间间隔内的第一时间发生的事件。 接收信号的第二状态的每个数字被表示为在时间码的对应时间间隔内的第二时间发生的事件，第一次与第二次可区分。