Gene useful for diagnosis and treatment of aplasia of corpus callosum and aspermatogenesis and use thereof
    1.
    发明授权
    Gene useful for diagnosis and treatment of aplasia of corpus callosum and aspermatogenesis and use thereof 失效
    用于诊断和治疗胼of体发育不全的基因和不典型生成及其用途

    公开(公告)号:US07081338B2

    公开(公告)日:2006-07-25

    申请号:US10314395

    申请日:2002-12-06

    IPC分类号: C12Q1/68 C12P19/34

    CPC分类号: C07K14/47 A61K38/00

    摘要: Aplasia of the corpus callosum or aspermatogenesis is diagnosed by investigating existence or expression of the BT-IgSF gene with use of a primer for PCR or probe for hybridization comprising a DNA coding for a novel cell adhesion molecule (BT-IgSF) defined in the following (A) or (B) or a partial sequence thereof: (A) a protein comprising the amino acid sequence of the amino acid numbers 1 to 409 of SEQ ID NO: 2; (B) a protein comprising an amino acid sequence of the amino acid numbers 1 to 409 of SEQ ID NO: 2 including substitution, deletion, insertion or addition of one or several amino acids and having a function as a cell adhesion molecule.

    摘要翻译: 通过使用PCR引物或用于杂交的探针研究BT-IgSF基因的存在或表达来诊断胼the体或异常生殖的发生,包括编码下述定义的新型细胞粘附分子(BT-IgSF)的DNA (A)或(B)或其部分序列:(A)包含SEQ ID NO:2的氨基酸编号1至409的氨基酸序列的蛋白质; (B)包含SEQ ID NO:2的氨基酸编号1至409的氨基酸序列的蛋白质,包括一个或几个氨基酸的取代,缺失,插入或添加并具有作为细胞粘附分子的功能。

    Method for diagnosing aplasia of corpus callosum
    2.
    发明授权
    Method for diagnosing aplasia of corpus callosum 失效
    诊断胼of体发育不良的方法

    公开(公告)号:US07217524B2

    公开(公告)日:2007-05-15

    申请号:US11409216

    申请日:2006-04-21

    IPC分类号: C12Q1/68 C12P19/34 C07H21/02

    CPC分类号: C07K14/47 A61K38/00

    摘要: Aplasia of the corpus callosum or aspermatogenesis is diagnosed by investigating existence or expression of the BT-IgSF gene with use of a primer for PCR or probe for hybridization comprising a DNA coding for a novel cell adhesion molecule (BT-IgSF) defined in the following (A) or (B) or a partial sequence thereof: (A) a protein comprising the amino acid sequence of the amino acid numbers 1 to 409 of SEQ ID NO: 2; (B) a protein comprising an amino acid sequence of the amino acid numbers 1 to 409 of SEQ ID NO: 2 including substitution, deletion, insertion or addition of one or several amino acids and having a function as a cell adhesion molecule.

    摘要翻译: 通过使用PCR引物或用于杂交的探针研究BT-IgSF基因的存在或表达来诊断胼the体或异常生殖的发生,包括编码下述定义的新型细胞粘附分子(BT-IgSF)的DNA (A)或(B)或其部分序列:(A)包含SEQ ID NO:2的氨基酸编号1至409的氨基酸序列的蛋白质; (B)包含SEQ ID NO:2的氨基酸编号1至409的氨基酸序列的蛋白质,包括一个或几个氨基酸的取代,缺失,插入或添加并具有作为细胞粘附分子的功能。

    Method for diagnosing aplasia of corpus callosum
    3.
    发明申请
    Method for diagnosing aplasia of corpus callosum 失效
    诊断胼of体发育不良的方法

    公开(公告)号:US20060178337A1

    公开(公告)日:2006-08-10

    申请号:US11409216

    申请日:2006-04-21

    CPC分类号: C07K14/47 A61K38/00

    摘要: Aplasia of the corpus callosum or aspermatogenesis is diagnosed by investigating existence or expression of the BT-IgSF gene with use of a primer for PCR or probe for hybridization comprising a DNA coding for a novel cell adhesion molecule (BT-IgSF) defined in the following (A) or (B) or a partial sequence thereof: (A) a protein comprising the amino acid sequence of the amino acid numbers 1 to 409 of SEQ ID NO: 2; (B) a protein comprising an amino acid sequence of the amino acid numbers 1 to 409 of SEQ ID NO: 2 including substitution, deletion, insertion or addition of one or several amino acids and having a function as a cell adhesion molecule.

    摘要翻译: 通过使用PCR引物或用于杂交的探针研究BT-IgSF基因的存在或表达来诊断胼the体或异常生殖的发生,包括编码下述定义的新型细胞粘附分子(BT-IgSF)的DNA (A)或(B)或其部分序列:(A)包含SEQ ID NO:2的氨基酸编号1至409的氨基酸序列的蛋白质; (B)包含SEQ ID NO:2的氨基酸编号1至409的氨基酸序列的蛋白质,包括一个或几个氨基酸的取代,缺失,插入或添加并具有作为细胞粘附分子的功能。