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公开(公告)号：US20140037690A1
公开(公告)日：2014-02-06
申请号：US14113198
申请日：2012-04-17
申请人： Hiroharu Kawahara , Yuichi Inque
发明人： Hiroharu Kawahara , Yuichi Inque
IPC分类号： A61K38/44
CPC分类号： A61K38/44 , A23L33/105 , C12Y102/01012
摘要： This invention provides an anti-allergic substance that effectively inhibits allergic symptoms by inhibiting production of the IgE antibody associated with the development of allergies. Anti-allergic substances, pharmaceutical products (i.e., anti-allergic agents), and food (i.e., food with health-promoting benefits) containing strawberry-derived glyceraldehyde-3-phosphate do not cause side effects such as those caused by steroids, and such substances can be consumed through daily meals and can alleviate allergic symptoms.
摘要翻译： 本发明提供了通过抑制与过敏发生相关的IgE抗体的产生来有效地抑制过敏症状的抗过敏物质。 含有草甘膦甘油醛-3-磷酸酯的抗过敏物质，药物（即抗过敏剂）和食品（即具有促进健康的食物）不会引起类固醇引起的副作用， 这些物质可以通过日常饮食消耗，并可以减轻过敏症状。
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公开(公告)号：US09511124B2
公开(公告)日：2016-12-06
申请号：US14113198
申请日：2012-04-17
申请人： Hiroharu Kawahara , Yuichi Inoue
发明人： Hiroharu Kawahara , Yuichi Inoue
CPC分类号： A61K38/44 , A23L33/105 , C12Y102/01012
摘要： This invention provides an anti-allergic substance that effectively inhibits allergic symptoms by inhibiting production of the IgE antibody associated with the development of allergies. Anti-allergic substances, pharmaceutical products (i.e., anti-allergic agents), and food (i.e., food with health-promoting benefits) containing strawberry-derived glyceraldehyde-3-phosphate do not cause side effects such as those caused by steroids, and such substances can be consumed through daily meals and can alleviate allergic symptoms.
摘要翻译： 本发明提供了通过抑制与过敏发生相关的IgE抗体的产生来有效地抑制过敏症状的抗过敏物质。 含有草甘膦甘油醛-3-磷酸酯的抗过敏物质，药物（即抗过敏剂）和食品（即具有促进健康的食物）不会引起类固醇引起的副作用， 这些物质可以通过日常饮食消耗，并可以减轻过敏症状。
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公开(公告)号：US6013518A
公开(公告)日：2000-01-11
申请号：US001995
申请日：1997-12-31
申请人： Kenkou Tsuji , Mari Yamamoto , Kazuhiro Osada , Hiroharu Kawahara
发明人： Kenkou Tsuji , Mari Yamamoto , Kazuhiro Osada , Hiroharu Kawahara
CPC分类号： C12N5/163 , C12N2500/25 , C12N2503/02
摘要： Provided are a human immunocompetent fused cell line, characterized in that any one of a mutant cell selected from the group consisting of ICLU-B, ICLU-T and ICLU-E is used as a parent cell line, wherein said mutant cell is obtained by selecting an 8-azaguanine- or 6-thioguanine-resistant clone from a human Burkitt lymphoma cell line Raji, a human T-cell lymphocytic leukemia cell line PEER and a human eosinophilic leukemia cell line EoL-1, and then treating said clone in order to capable of serum-free culture, and a method of obtaining said human immunocompetent fused cell line.The human immunocoipetent fused cell line obtained by the present invention is used to investigate food functions, novel drugs and production thereof with the view to the elucidation of mechanisms of phenomena of an immune system such as allergies, cancers and the like using human cell lines, and the prevention, diagnosis and therapy of these diseases.
摘要翻译： 提供一种人免疫活性融合细胞系，其特征在于，使用选自ICLU-B，ICLU-T和ICLU-E的突变细胞中的任一种作为亲本细胞系，其中所述突变细胞通过 从人类伯基特淋巴瘤细胞系Raji，人T细胞淋巴细胞白血病细胞系PEER和人嗜酸粒细胞白血病细胞系EoL-1中选择8-氮鸟嘌呤或6-硫鸟嘌呤抗性克隆，然后按顺序处理所述克隆 能够进行无血清培养，以及获得所述人免疫活性融合细胞系的方法。 本发明获得的人免疫融合细胞系用于研究食物功能，新药及其生产，以便使用人细胞系阐明免疫系统如过敏，癌症等现象的机制， 以及这些疾病的预防，诊断和治疗。
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4.发明授权Human cell strains for protein production, provided by selecting strains with high intracellular protein and mutating with carcinogens 失效通过选择具有高细胞内蛋白质的菌株和用致癌物突变提供的用于蛋白质生产的人类细胞株公开(公告)号：US07678570B2
公开(公告)日：2010-03-16
申请号：US10591521
申请日：2004-10-27
申请人： Hiroharu Kawahara
发明人： Hiroharu Kawahara
CPC分类号： C12N5/0694 , C12N2510/02
摘要： A novel human cell strain enabling the continuous production of a desired protein with high efficiency, comprising a novel human cell strain established by transforming a human cell strain whose total intracellular protein weight is 0.1 to 1 mg per 1,000,000 cells; with the novel human cell strain being further characterized in that after a gene encoding a desired protein is transfected into it, the transfected cell is subsequently cultured.
摘要翻译： 一种能够高效连续生产所需蛋白质的新型人类细胞株，其包含通过转化总细胞内蛋白质重量为0.1至1mg / 1,000,000个细胞的人细胞株而建立的新型人类细胞株; 新型人类细胞株的进一步特征在于，将编码所需蛋白质的基因转染入其后，随后培养转染的细胞。
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公开(公告)号：US5739540A
公开(公告)日：1998-04-14
申请号：US668230
申请日：1996-06-21
摘要： A nuclear medicine diagnostic apparatus, particularly involving emission computed tomography, wherein absorption correction is performed by a gamma ray source including a plurality of line sources arrayed in a common plane. Each line source produces a radiation distribution having a peak and defining a half-width distance at which the radiation from the line source is attenuated by one-half. The plurality of line sources are arranged at a pitch equal to the half-width distance or an integral multiple of the half-width distance. In one embodiment, a serpentine line source is used having straight line portions and a plurality of bent portions, with the straight line portions arrayed parallel to each other at a pitch equal to the half-width distance or an integral multiple of the half-width distance.
摘要翻译： 一种核医学诊断装置，特别涉及发射计算机断层摄影，其中，由包括排列在公共平面中的多个线源的伽马射线源执行吸收校正。 每个线源产生具有峰值并限定半线宽度距离的辐射分布，在该距离处来自线源的辐射被衰减一半。 多个线源以等于半宽度距离或半角距离的整数倍的间距排列。 在一个实施例中，使用具有直线部分和多个弯曲部分的蛇形线源，其中直线部分以等于半宽度距离的间距或半宽度的整数倍彼此平行排列 距离。
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6.发明申请Human cell strains for protein production, provided by selecting strains with high intracellular protein and mutating with carcinogens 失效通过选择具有高细胞内蛋白质的菌株和用致癌物突变提供的用于蛋白质生产的人类细胞株公开(公告)号：US20070196896A1
公开(公告)日：2007-08-23
申请号：US10591521
申请日：2004-10-27
申请人： Hiroharu Kawahara
发明人： Hiroharu Kawahara
CPC分类号： C12N5/0694 , C12N2510/02
摘要： A novel human cell strain enabling the continuous production of a desired protein with high efficiency, comprising a novel human cell strain established by transforming a human cell strain whose total intracellular protein weight is 0.1 to 1 mg 1,000,000 cells; with the novel human cell strain being further characterized in that after a gene encoding a desired protein is transfected into it, the transfected cell is subsequently cultured.
摘要翻译： 一种能够高效连续生产所需蛋白质的新型人类细胞株，包括通过转化总细胞内蛋白质重量为0.1至1mg 1,000,000个细胞的人类细胞株建立的新型人类细胞株; 新型人类细胞株的进一步特征在于，将编码所需蛋白质的基因转染入其后，随后培养转染的细胞。
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