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公开(公告)号：US06899893B2
公开(公告)日：2005-05-31
申请号：US10417254
申请日：2003-04-17
IPC分类号： A23G3/34 , A23G4/00 , A23L1/30 , A61K8/00 , A61K8/60 , A61K8/97 , A61K9/00 , A61K31/05 , A61K31/7024 , A61K31/7032 , A61P29/00 , A61P37/08 , A61Q19/10 , C07H13/08 , C12N15/09 , A61K47/00
CPC分类号： A61K31/05 , A61K8/60 , A61K8/97 , A61K9/0056 , A61Q19/10 , Y10S514/844 , Y10S514/845 , Y10S514/846 , Y10S514/847 , Y10S514/848
摘要： This invention is to provide an agent for therapy and prevention of allergic diseases which has no adverse action, shows a high safety even by administration for a long period and is able to be utilized to food and/or beverage, cosmetics, etc. which are used daily. To be specific, it provides antiallergic agent and anti-inflammatory agent characterized in containing at least one polyphenol selected from strictinin and methylated derivatives thereof as an effective ingredient; a method for the addition of an antiallergic agent for oral administration or an anti-inflammatory agent for oral administration which is characterized in containing at least one polyphenol selected from strictinin and methylated derivatives thereof as an effective ingredient to food and/or beverage for prevention, suppression and mitigation of allergic symptoms or inflammatory symptoms.
摘要翻译： 本发明提供一种治疗和预防过敏性疾病的药剂，其不会产生不良反应，即使长时间施用也能显示高安全性，并且能够用于食品和/或饮料，化妆品等 每天使用 具体而言，提供抗变应性剂和抗炎剂，其特征在于含有至少一种选自严格菌素及其甲基化衍生物的多酚作为有效成分; 用于口服给药的抗过敏剂或口服抗炎剂的添加方法，其特征在于，含有至少一种选自其严格抑制素和甲基化衍生物的多酚作为有效成分用于预防食品和/或饮料， 抑制和缓解过敏症状或炎症症状。
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公开(公告)号：US06638524B2
公开(公告)日：2003-10-28
申请号：US10131211
申请日：2002-04-25
IPC分类号： A61K4700
CPC分类号： A61K31/05 , A61K8/60 , A61K8/97 , A61K9/0056 , A61Q19/10 , Y10S514/844 , Y10S514/845 , Y10S514/846 , Y10S514/847 , Y10S514/848
摘要： This invention is to provide an agent for therapy and prevention of allergic diseases which has no adverse action, shows a high safety even by administration for a long period and is able to be utilized to food and/or beverage, cosmetics, etc. which are used daily. To be specific, it provides antiallergic agent and anti-inflammatory agent characterized in containing at least one polyphenol selected from strictinin and methylated derivatives thereof as an effective ingredient; a method for the addition of an antiallergic agent for oral administration or an anti-inflammatory agent for oral administration which is characterized in containing at least one polyphenol selected from strictinin and methylated derivatives thereof as an effective ingredient to food and/or beverage for prevention, suppression and mitigation of allergic symptoms or inflammatory symptoms.
摘要翻译： 本发明提供一种治疗和预防过敏性疾病的药剂，其不会产生不良反应，即使长时间施用也能显示高安全性，并且能够用于食品和/或饮料，化妆品等 每天使用 具体而言，提供抗变应性剂和抗炎剂，其特征在于含有至少一种选自严格菌素及其甲基化衍生物的多酚作为有效成分; 用于口服给药的抗过敏剂或口服抗炎剂的添加方法，其特征在于，含有至少一种选自其严格抑制素和甲基化衍生物的多酚作为有效成分用于预防食品和/或饮料， 抑制和缓解过敏症状或炎症症状。
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公开(公告)号：US06491943B2
公开(公告)日：2002-12-10
申请号：US09778820
申请日：2001-02-08
IPC分类号： A61K4700
CPC分类号： A61K31/05 , A61K8/60 , A61K8/97 , A61K9/0056 , A61Q19/10 , Y10S514/844 , Y10S514/845 , Y10S514/846 , Y10S514/847 , Y10S514/848
摘要： This invention is to provide an agent for therapy and prevention of allergic diseases which has no adverse action, shows a high safety even by administration for a long period and is able to be utilized to food and/or beverage, cosmetics, etc. which are used daily. To be specific, it provides antiallergic agent and anti-inflammatory agent characterized in containing at least one polyphenol selected from strictinin and methylated derivatives thereof as an effective ingredient; a method for the addition of an antiallergic agent for oral administration or an anti-inflammatory agent for oral administration which is characterized in containing at least one polyphenol selected from strictinin and methylated derivatives thereof as an effective ingredient to food and/or beverage for prevention, suppression and mitigation of allergic symptoms or inflammatory symptoms.
摘要翻译： 本发明提供一种治疗和预防过敏性疾病的药剂，其不会产生不良反应，即使长时间施用也能显示高安全性，并且能够用于食品和/或饮料，化妆品等 每天使用 具体而言，提供抗变应性剂和抗炎剂，其特征在于含有至少一种选自严格菌素及其甲基化衍生物的多酚作为有效成分; 用于口服给药的抗过敏剂或口服抗炎剂的添加方法，其特征在于，含有至少一种选自其严格抑制素和甲基化衍生物的多酚作为有效成分用于预防食品和/或饮料， 抑制和缓解过敏症状或炎症症状。
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公开(公告)号：US6013518A
公开(公告)日：2000-01-11
申请号：US001995
申请日：1997-12-31
申请人： Kenkou Tsuji , Mari Yamamoto , Kazuhiro Osada , Hiroharu Kawahara
发明人： Kenkou Tsuji , Mari Yamamoto , Kazuhiro Osada , Hiroharu Kawahara
CPC分类号： C12N5/163 , C12N2500/25 , C12N2503/02
摘要： Provided are a human immunocompetent fused cell line, characterized in that any one of a mutant cell selected from the group consisting of ICLU-B, ICLU-T and ICLU-E is used as a parent cell line, wherein said mutant cell is obtained by selecting an 8-azaguanine- or 6-thioguanine-resistant clone from a human Burkitt lymphoma cell line Raji, a human T-cell lymphocytic leukemia cell line PEER and a human eosinophilic leukemia cell line EoL-1, and then treating said clone in order to capable of serum-free culture, and a method of obtaining said human immunocompetent fused cell line.The human immunocoipetent fused cell line obtained by the present invention is used to investigate food functions, novel drugs and production thereof with the view to the elucidation of mechanisms of phenomena of an immune system such as allergies, cancers and the like using human cell lines, and the prevention, diagnosis and therapy of these diseases.
摘要翻译： 提供一种人免疫活性融合细胞系，其特征在于，使用选自ICLU-B，ICLU-T和ICLU-E的突变细胞中的任一种作为亲本细胞系，其中所述突变细胞通过 从人类伯基特淋巴瘤细胞系Raji，人T细胞淋巴细胞白血病细胞系PEER和人嗜酸粒细胞白血病细胞系EoL-1中选择8-氮鸟嘌呤或6-硫鸟嘌呤抗性克隆，然后按顺序处理所述克隆 能够进行无血清培养，以及获得所述人免疫活性融合细胞系的方法。 本发明获得的人免疫融合细胞系用于研究食物功能，新药及其生产，以便使用人细胞系阐明免疫系统如过敏，癌症等现象的机制， 以及这些疾病的预防，诊断和治疗。
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