公开(公告)号：US20130345434A1

公开(公告)日：2013-12-26

申请号：US14003089

申请日：2012-02-28

申请人： Hisaaki Kanda ,  Hirotsugu Konishi ,  Hiroki Yamaguchi

发明人： Hisaaki Kanda ,  Hirotsugu Konishi ,  Hiroki Yamaguchi

IPC分类号： C07D275/04 ,  C07C319/12

CPC分类号： C07D275/04 ,  C07C319/02 ,  C07C319/12 ,  C07C319/14 ,  Y02P20/582 ,  C07C323/62 ,  C07C321/04

摘要： The present invention provides a method for producing a 1,2-benzisothiazol-3-one compound by reacting a 2-(alkylthio)benzonitrile compound with a halogenating agent in the presence of water, wherein an alkyl halide that is generated as by-product is reacted with a sulfide to form an alkylthiol, which is converted into an alkali metal salt, and then the resulting alkali metal salt is reacted with a 2-halobenzonitrile compound to be converted into a 2-(alkylthio)benzonitrile compound and reused as a starting material for the production of a 1,2-benzisothiazol-3-one compound. By means of the present invention, it is possible to efficiently use the by-product that is generated during the production of a 1,2-benzisothiazol-3-one compound and economically produce a 1,2-benzisothiazol-3-one compound without placing a burden on the environment.

摘要翻译： 本发明提供了在水存在下使2-（烷硫基）苄腈化合物与卤化剂反应制备1,2-苯并异噻唑-3-酮化合物的方法，其中产生副产物的烷基卤 与硫化物反应形成烷基硫醇，将其转化为碱金属盐，然后将所得碱金属盐与2-卤代苯甲腈化合物反应，转化为2-（烷硫基）苄腈化合物，并重复使用 用于制备1,2-苯并异噻唑-3-酮化合物的原料。 通过本发明，可以有效地利用在1,2-苯并异噻唑-3-酮化合物生产过程中产生的副产物，并且经济地制备1,2-苯并异噻唑-3-酮化合物而没有 给环境造成负担。

公开(公告)号：US09365507B2

公开(公告)日：2016-06-14

申请号：US13583730

申请日：2011-03-09

申请人： Paul Kuad ,  Hisaaki Kanda ,  Takeshi Fujiwara ,  Hiroyuki Shiraishi

发明人： Paul Kuad ,  Hisaaki Kanda ,  Takeshi Fujiwara ,  Hiroyuki Shiraishi

IPC分类号： C07C317/14 ,  C07C323/65

CPC分类号： C07C323/65

摘要： The present invention provides a diaryl sulfone compound represented by Formula (1): wherein R1 to R4 and R1′ to R4′ are the same or different, and each represents hydrogen, C1-4 alkyl, or halogen, and R5 represents C2-6 alkenyl, C1-4 alkyl, or aromatic heterocyclic group; a method for producing the diaryl sulfone compound represented by Formula (1) by reacting a 4,4′-dihaloarylsulfone compound with thiol salt compound having an alkylene group; and a method for producing the diaryl sulfone compound represented by Formula (1) by reacting a 4,4′-dihaloarylsulfone compound with a thiol salt compound having a hydroxyl group, and subjecting the resulting compound to reaction with a halogenating agent, followed by a dehydrohalogenation reaction.

摘要翻译： 本发明提供由式（1）表示的二芳基砜化合物：其中R1至R4和R1'至R4'相同或不同，各自表示氢，C1-4烷基或卤素，R5表示C2-6 烯基，C 1-4烷基或芳族杂环基; 通过使4,4'-二卤代芳基砜化合物与具有亚烷基的硫醇盐化合物反应制备由式（1）表示的二芳基砜化合物的方法; 以及通过使4,4'-二卤代芳基砜化合物与具有羟基的硫醇盐化合物反应制造由式（1）表示的二芳基砜化合物的方法，并使所得化合物与卤化剂反应，接着， 脱卤化氢反应。

公开(公告)号：US20140012018A1

公开(公告)日：2014-01-09

申请号：US13979953

申请日：2011-12-27

申请人： Masayoshi Miyada ,  Katsumi Takano ,  Hisaaki Kanda

发明人： Masayoshi Miyada ,  Katsumi Takano ,  Hisaaki Kanda

IPC分类号： C09K3/00

CPC分类号： C09K3/00 ,  C07D333/48

摘要： The present invention aims to provide, with combination of a sulfolane compound and an organic alkanolamine compound, a sulfolane composition which is not likely to cause odor, can suppress pyrolysis of the sulfolane compound with a reduced amount of additives, and can reduce generation of sulfur dioxide. The present invention relates to a sulfolane composition containing a sulfolane compound represented by formula (1) and an organic alkanolamine compound, wherein R1 to R6 each independently represent a hydrogen atom or a C1-6 alkyl group.

摘要翻译： 本发明的目的在于提供环丁砜化合物和有机链烷醇胺化合物的组合，不易引起气味的环丁砜组合物可以抑制环丁砜化合物的热解，并减少硫的产生 二氧化碳 本发明涉及含有式（1）表示的环丁砜化合物和有机链烷醇胺化合物的环丁砜组合物，其中，R1〜R6各自独立地表示氢原子或C1-6烷基。

公开(公告)号：US20130005982A1

公开(公告)日：2013-01-03

申请号：US13583730

申请日：2011-03-09

申请人： Paul Kuad ,  Hisaaki Kanda ,  Takeshi Fujiwara ,  Hiroyuki Shiraishi

发明人： Paul Kuad ,  Hisaaki Kanda ,  Takeshi Fujiwara ,  Hiroyuki Shiraishi

IPC分类号： C07C323/65 ,  C07D277/74 ,  C07C319/14

CPC分类号： C07C323/65

摘要： The present invention provides a diaryl sulfone compound represented by Formula (1): wherein R1 to R4 and R1′ to R4′ are the same or different, and each represents hydrogen, C1-4 alkyl, or halogen, and R5 represents C2-6 alkenyl, C1-4 alkyl, or aromatic heterocyclic group; a method for producing the diaryl sulfone compound represented by Formula (1) by reacting a 4,4′-dihaloarylsulfone compound with thiol salt compound having an alkylene group; and a method for producing the diaryl sulfone compound represented by Formula (1) by reacting a 4,4′-dihaloarylsulfone compound with a thiol salt compound having a hydroxyl group, and subjecting the resulting compound to reaction with a halogenating agent, followed by a dehydrohalogenation reaction.

摘要翻译： 本发明提供由式（1）表示的二芳基砜化合物：其中R1至R4和R1'至R4'相同或不同，各自表示氢，C1-4烷基或卤素，R5表示C2-6 烯基，C 1-4烷基或芳族杂环基; 通过使4,4'-二卤代芳基砜化合物与具有亚烷基的硫醇盐化合物反应制备由式（1）表示的二芳基砜化合物的方法; 以及通过使4,4'-二卤代芳基砜化合物与具有羟基的硫醇盐化合物反应制造由式（1）表示的二芳基砜化合物的方法，并使所得化合物与卤化剂反应，接着， 脱卤化氢反应。

公开(公告)号：US08436193B2

公开(公告)日：2013-05-07

申请号：US13131471

申请日：2009-11-30

申请人： Seiji Bando ,  Hisaaki Kanda ,  Yuichi Onoda ,  Masayoshi Miyada

发明人： Seiji Bando ,  Hisaaki Kanda ,  Yuichi Onoda ,  Masayoshi Miyada

IPC分类号： C07D333/48

CPC分类号： C07D333/48

摘要： An object of the present invention is to provide a method for manufacturing a sulfolene compound, the method being capable of inhibiting generation of polymers. Another object of the present invention is to provide a method for manufacturing a sulfolane compound, the method being capable of controlling inhibition of hydrogenation catalyst activity and smoothly hydrogenating a sulfolene compound.The present invention is a method for manufacturing a sulfolene compound represented by a formula (2), which comprises the step of reacting a conjugated diene compound represented by a formula (1) with sulfur dioxide in the presence of a metallocene compound: in the formula (1), R1 to R6 each independently represents a hydrogen atom or a C1 to C6 alkyl group, in the formula (2), R1 to R6 represent the same groups represented by R1 to R6 in the formula (1).

摘要翻译： 本发明的目的是提供一种制备环丁烯砜化合物的方法，该方法能够抑制聚合物的产生。 本发明的另一个目的是提供一种制备环丁砜化合物的方法，该方法能够控制氢化催化剂活性的抑制和平滑氢化环丁烯砜化合物。 本发明是一种制备由式（2）表示的环丁烯烯化合物的方法，其包括使式（1）表示的共轭二烯化合物与二氧化硫在茂金属化合物存在下反应的步骤：式 （1）中，R 1〜R 6各自独立地表示氢原子或C 1〜C 6烷基，式（2）中，R 1〜R 6表示与式（1）中的R 1〜R 6相同的基团。

公开(公告)号：US09040724B2

公开(公告)日：2015-05-26

申请号：US13583725

申请日：2011-03-09

申请人： Paul Kuad ,  Hisaaki Kanda ,  Takeshi Fujiwara ,  Hiroyuki Shiraishi

发明人： Paul Kuad ,  Hisaaki Kanda ,  Takeshi Fujiwara ,  Hiroyuki Shiraishi

IPC分类号： C07C323/65 ,  C07C327/06 ,  C07D331/02 ,  C07C319/06

CPC分类号： C07C323/65 ,  C07C319/06 ,  C07C327/06 ,  C07D331/02

摘要： The present invention provides a diaryl sulfone compound represented by Formula (1) below: wherein R1 to R4 and R1′ to R4′ are the same or different; each represents hydrogen, C1-4 alkyl, or halogen; and R5 is (thio)glycidyl, acryloyl, or the like; and a method for producing the same. According to the present invention, a novel compound useful as a monomer for producing synthetic resin having a high refractive index and excellent transparency for optical materials can be efficiently produced with a simple production process, using an inexpensive material as a starting material.

摘要翻译： 本发明提供由下式（1）表示的二芳基砜化合物：其中R1至R4和R1'至R4'相同或不同; 各自表示氢，C 1-4烷基或卤素; 并且R 5为（硫基）缩水甘油基，丙烯酰基等; 及其制造方法。 根据本发明，通过使用廉价的材料作为原料，可以通过简单的制造方法有效地制造用作制备具有高折射率和优异的光学材料透明性的合成树脂的单体的新型化合物。

公开(公告)号：US20130005993A1

公开(公告)日：2013-01-03

申请号：US13583725

申请日：2011-03-09

申请人： Paul Kuad ,  Hisaaki Kanda ,  Takeshi Fujiwara ,  Hiroyuki Shiraishi

发明人： Paul Kuad ,  Hisaaki Kanda ,  Takeshi Fujiwara ,  Hiroyuki Shiraishi

IPC分类号： C07D405/12 ,  C07C315/04 ,  C07C321/28 ,  C07C319/02 ,  C07D409/12 ,  C07C317/24

CPC分类号： C07C323/65 ,  C07C319/06 ,  C07C327/06 ,  C07D331/02

摘要： The present invention provides a diaryl sulfone compound represented by Formula (1) below: wherein R1 to R4 and R1′ to R4′ are the same or different; each represents hydrogen, C1-4 alkyl, or halogen; and R5 is (thio)glycidyl, acryloyl, or the like; and a method for producing the same.According to the present invention, a novel compound useful as a monomer for producing synthetic resin having a high refractive index and excellent transparency for optical materials can be efficiently produced with a simple production process, using an inexpensive material as a starting material.

摘要翻译： 本发明提供由下式（1）表示的二芳基砜化合物：其中R1至R4和R1'至R4'相同或不同; 各自表示氢，C 1-4烷基或卤素; 并且R 5为（硫基）缩水甘油基，丙烯酰基等; 及其制造方法。 根据本发明，通过使用廉价的材料作为原料，可以通过简单的制造方法有效地制造用作制备具有高折射率和优异的光学材料透明性的合成树脂的单体的新型化合物。

公开(公告)号：US20110288307A1

公开(公告)日：2011-11-24

申请号：US13131471

申请日：2009-11-30

申请人： Seiji Bando ,  Hisaaki Kanda ,  Yuichi Onoda ,  Masayoshi Miyada

发明人： Seiji Bando ,  Hisaaki Kanda ,  Yuichi Onoda ,  Masayoshi Miyada

IPC分类号： C07D333/48

CPC分类号： C07D333/48

摘要： An object of the present invention is to provide a method for manufacturing a sulfolene compound, the method being capable of inhibiting generation of polymers. Another object of the present invention is to provide a method for manufacturing a sulfolane compound, the method being capable of controlling inhibition of hydrogenation catalyst activity and smoothly hydrogenating a sulfolene compound.The present invention is a method for manufacturing a sulfolene compound represented by a formula (2), which comprises the step of reacting a conjugated diene compound represented by a formula (1) with sulfur dioxide in the presence of a metallocene compound: in the formula (1), R1 to R6 each independently represents a hydrogen atom or a C1 to C6 alkyl group, in the formula (2), R1 to R6 represent the same groups represented by R1 to R6 in the formula (1).

摘要翻译： 本发明的目的是提供一种制备环丁烯砜化合物的方法，该方法能够抑制聚合物的产生。 本发明的另一个目的是提供一种制备环丁砜化合物的方法，该方法能够控制氢化催化剂活性的抑制和平滑氢化环丁烯砜化合物。 本发明是一种制备由式（2）表示的环丁烯烯化合物的方法，其包括使式（1）表示的共轭二烯化合物与二氧化硫在茂金属化合物存在下反应的步骤：式 （1）中，R 1〜R 6各自独立地表示氢原子或C 1〜C 6烷基，式（2）中，R 1〜R 6表示与式（1）中的R 1〜R 6相同的基团。