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    Method for the improvement of transport across adaptable semi-permeable barriers
    1.
    发明授权
    Method for the improvement of transport across adaptable semi-permeable barriers 失效
    改善穿过适应性半渗透屏障的运输方法

    公开(公告)号：US07591949B2

    公开(公告)日：2009-09-22

    申请号：US10984450

    申请日：2004-11-08

    申请人： Gregor Cevc ,  Holger Richardsen ,  Andrea Weiland-Waibel

    发明人： Gregor Cevc ,  Holger Richardsen ,  Andrea Weiland-Waibel

    IPC分类号： B01D61/00 ,  A61K9/127

    CPC分类号： A61K9/7023 ,  A61K9/1272

    摘要： The invention relates to a method, a kit and a device for controlling the flux of penetrants across an adaptable semi-permeable porous barrier, the method comprising the steps of: preparing a formulation by suspending or dispersing said penetrants in a polar liquid in the form of fluid droplets surrounded by a membrane-like coating of one or several layers, said coating comprising at least two kinds of forms of amphiphilic substances with a tendency to aggregate, said penetrants being able to transport agents through the pores of said barrier or to enable agent permeation through the pores of said barrier after penetrants have entered the pores, selecting a dose amount of said penetrants to be applied on a predetermined area of said barrier to control the flux of said penetrants across said barrier, and applying the selected dose amount of said formulation containing said penetrants onto said area of said porous barrier.

    摘要翻译： 本发明涉及一种方法，试剂盒和用于控制穿过适应性半透性多孔屏障的渗透剂通量的装置，所述方法包括以下步骤：通过将所述渗透剂悬浮或分散在极性液体中形式 由一层或几层的膜状涂层包围的流体液滴，所述涂层包含至少两种具有聚集倾向的两亲物质形式，所述渗透剂能够将物质输送通过所述屏障的孔或使得能够 在渗透剂进入孔之后，试剂通过所述阻挡层的孔渗透，选择施用在所述屏障的预定区域上的所述渗透剂的剂量，以控制穿过所述屏障的所述渗透剂的通量，并施加所选择的剂量 所述制剂含有所述渗透剂到所述多孔屏障的所述区域上。

    Method for the improvement of transport across adaptable semi-permeable barriers
    3.
    发明授权
    Method for the improvement of transport across adaptable semi-permeable barriers 失效
    改善穿过适应性半渗透屏障的运输方法

    公开(公告)号：US07459171B2

    公开(公告)日：2008-12-02

    申请号：US10037480

    申请日：2002-01-04

    申请人： Gregor Cevc ,  Holger Richardsen ,  Andrea Weiland-Waibel

    发明人： Gregor Cevc ,  Holger Richardsen ,  Andrea Weiland-Waibel

    IPC分类号： A61K13/00 ,  A61K9/70 ,  A61K9/127 ,  B01D61/00 ,  B01D63/00

    CPC分类号： A61K9/7023 ,  A61K9/1272

    摘要： The invention relates to a method, a kit and a device for controlling the flux of penetrants across an adaptable semi-permeable porous barrier, the method comprising the steps of: preparing a formulation by suspending or dispersing said penetrants in a polar liquid in the form of fluid droplets surrounded by a membrane-like coating of one or several layers, said coating comprising at least two kinds of forms of amphiphilic substances with a tendency to aggregate, said penerants being able to transport agents through the pores of said barrier or to enable agent permeation through the pores of said barrier after penetrants have entered the pores, selecting a dose amount of said penetrants to be applied on a predetermined area of said barrier to control the flux of said penetrants across said barrier, and applying the selected dose amount of said formulation containing said penetrants onto said area of said porous barrier.

    摘要翻译： 本发明涉及一种方法，试剂盒和用于控制穿过适应性半透性多孔屏障的渗透剂通量的装置，所述方法包括以下步骤：通过将所述渗透剂悬浮或分散在极性液体中形式 由一层或多层的膜状涂层包围的流体液滴，所述涂层包含至少两种倾向于聚集的两亲物质的形式，所述聚合器能够将试剂输送通过所述屏障的孔或使得能够 在渗透剂进入孔之后，试剂通过所述阻挡层的孔渗透，选择施用在所述屏障的预定区域上的所述渗透剂的剂量，以控制穿过所述屏障的所述渗透剂的通量，并施加所选择的剂量 所述制剂含有所述渗透剂到所述多孔屏障的所述区域上。