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    DENDRIMER HYDROGELS
    4.
    发明申请
    DENDRIMER HYDROGELS 审中-公开

    公开(公告)号：US20110189291A1

    公开(公告)日：2011-08-04

    申请号：US13022974

    申请日：2011-02-08

    Applicant: Hu Yang ,  Pooja N. Desai ,  Christopher A. Holden ,  Uday B. Kompella ,  Puneet Tyagi

    Inventor： Hu Yang ,  Pooja N. Desai ,  Christopher A. Holden ,  Uday B. Kompella ,  Puneet Tyagi

    IPC: A61K9/00 ,  A61K31/5377 ,  A61P27/02

    CPC classification number: A61K9/00 ,  A61K31/5377

    Abstract: Photoactivatable dendrimers and hydrogels formed therefrom include dendrimers to which polymer chains (e.g. polyethylene glycol, PEG) have been conjugated; and reactive photoactivatable groups attached to terminal functional groups of the polymer chains (e.g. hydroxyls of PEG). Exposure to a suitable wavelength of light activates the photoactivatable groups, which then crosslink with one another, thereby forming a hydrogel. The hydrogel may also include one or more agents of interest; or, in some embodiments, nanoparticles containing one or more agents of interest may be dispersed in the hydrogel. These formulations are well-suited for sustained or prolonged delivery of active agents, e.g. for the treatment of glaucoma by the sustained delivery of anti-glaucoma agents directly to the eye.

    Abstract translation: 可光活化的树枝状大分子和由其形成的水凝胶包括聚合物链（例如聚乙二醇，PEG）已经共轭的树枝状大分子; 和连接到聚合物链的末端官能团（例如PEG的羟基）上的活性可光活化基团。 暴露于适当波长的光激活可光活化的基团，然后其彼此交联，从而形成水凝胶。 水凝胶还可以包括一种或多种感兴趣的试剂; 或者在一些实施方案中，含有一种或多种感兴趣的试剂的纳米颗粒可以分散在水凝胶中。 这些制剂非常适合于活性剂的持续或长期递送，例如， 用于通过将抗青光眼剂直接持续递送至眼睛来治疗青光眼。

    Olefin waxes having improved hardness or viscosity
    5.
    发明授权
    Olefin waxes having improved hardness or viscosity 有权
    具有改善的硬度或粘度的烯烃蜡

    公开(公告)号：US07828957B2

    公开(公告)日：2010-11-09

    申请号：US12430586

    申请日：2009-04-27

    Applicant: Hu Yang ,  Eduardo J Baralt ,  Willie J Isom ,  Ronald G Abbott

    Inventor： Hu Yang ,  Eduardo J Baralt ,  Willie J Isom ,  Ronald G Abbott

    IPC: C07C27/12 ,  C08L91/06 ,  C09D191/06

    CPC classification number: C08L91/06 ,  C08F8/06 ,  C08F10/14

    Abstract: In one embodiment, we disclose hardened olefin waxes and processes for preparing them. In another embodiment, we disclose oxidized olefin waxes having low viscosity and processes for preparing them. The waxes are suitable for use as polishes, coatings, or inks, among other uses. For example, a hardened olefin wax composition produced from a feedstock olefin wax composition by contacting the feedstock olefin wax composition with an oxygen-containing gas at a temperature greater than a melting point of the feedstock olefin wax composition, the hardened olefin wax composition having: a needle penetration value at 25° C. at least 5 percent less than a needle penetration value at 25° C. of the feedstock olefin wax composition; a a kinematic viscosity at 100° C. of up to about 200% greater than the kinematic viscosity of the feedstock olefin wax composition; and a saponification number less than 5 mg KOH/g hardened olefin wax composition.

    Abstract translation: 在一个实施方案中，我们公开了硬化烯烃蜡及其制备方法。 在另一个实施方案中，我们公开了具有低粘度的氧化烯烃蜡和其制备方法。 该蜡适合用作抛光剂，涂料或油墨以及其他用途。 例如，由原料烯烃蜡组合物制备的硬化烯烃蜡组合物通过在原料烯烃蜡组合物的熔点以上的温度下使原料烯烃蜡组合物与含氧气体接触，所述硬化的烯烃蜡组合物具有： 在25℃下的针穿透值比原料烯烃蜡组合物在25℃下的针穿透值小至少5％; 在100℃下的运动粘度高达原料烯烃蜡组合物的运动粘度高达约200％; 皂化值小于5mg KOH / g硬化烯烃蜡组合物。

    Oxygen scavenging compositions comprising polymers derived from benzenedimethanol monomers
    8.
    发明授权
    Oxygen scavenging compositions comprising polymers derived from benzenedimethanol monomers 有权
    含氧清除组合物包含衍生自苯二甲醇单体的聚合物

    公开(公告)号：US07022258B2

    公开(公告)日：2006-04-04

    申请号：US10076064

    申请日：2002-02-14

    Applicant: Hu Yang ,  Ta Yen Ching ,  Steven Woodcock

    Inventor： Hu Yang ,  Ta Yen Ching ,  Steven Woodcock

    IPC: C09K15/02 ,  C09K15/06 ,  C09K15/08 ,  B32B1/08

    CPC classification number: C09K15/06 ,  B65D81/267 ,  C08G63/18 ,  Y10T428/1341

    Abstract: Herein is disclosed an oxygen scavenging composition, comprising (i) an oxygen scavenging polymer comprising structure I: X—R—X—O—CH2—Ar—CH2—O,  (I) wherein —R— is selected from the group consisting of C1–C24 alkyl, C1–C24 substituted alkyl, C6–C24 aryl, and C6–C24 substituted aryl; —Ar— is selected from the group consisting of C6–C24 aryl and C6–C24 substituted aryl; and —X— is selected from the group consisting of null and —C(═O)—; (ii) a transition metal oxidation catalyst; and (iii) an energy-absorbing compound selected from the group consisting of microwave reactive materials and photoinitiators having a wavelength of maximum absorption of electromagnetic radiation from about 200 nm to about 750 nm. The oxygen scavenging composition can be used to form an oxygen barrier packaging article.

    Abstract translation: 本文公开了一种除氧组合物，其包含（i）包含结构I的氧清除聚合物：<？in-line-formula description =“In-line Formulas”end =“lead”？> img id =“PRIVATE-USE “=”7.20mm“wi =”8.47mm“file =”US07022258-20060404-Parenopenst.TIF“alt =”私人使用字符Parenopenst“img-content =”character“img-format =”tif“ /> XRXO-CH 2 -Ar-CH 2 -O ，（I）<？in-line-formula description = “在线式”末端=“尾”→其中-R-选自C 1 -C 12烷基，C 1 取代的C 2 -C 24烷基，C 6 -C 24芳基和C 6 -C 取代的芳基; -Ar-选自C 6 -C 24 - 芳基和C 6 -C 24 - 芳基。 取代芳基; 且-X-选自无效和-C（-O） - ; （ii）过渡金属氧化催化剂; 和（iii）选自微波反应物质和具有约200nm至约750nm的电磁辐射的最大吸收波长的光引发剂的能量吸收化合物。 氧气清除组合物可用于形成氧气阻隔性包装制品。

    Vinyl crosslinked oxygen scavenging compositions and methods of preparing the same
    9.
    发明授权
    Vinyl crosslinked oxygen scavenging compositions and methods of preparing the same 失效
    乙烯基交联氧清除组合物及其制备方法

    公开(公告)号：US06572783B1

    公开(公告)日：2003-06-03

    申请号：US09722374

    申请日：2000-11-27

    Applicant: Gangfeng Cai ,  Ta Yen Ching ,  Hu Yang

    Inventor： Gangfeng Cai ,  Ta Yen Ching ,  Hu Yang

    IPC: B01J2026

    CPC classification number: B01J31/04 ,  A23L3/3436 ,  B01J20/26 ,  B01J31/06 ,  C08K2201/012 ,  C09D7/65 ,  Y10T428/1321 ,  Y10T428/1334

    Abstract: The disclosed invention is directed to an oxygen scavenging composition that comprises at least one oxygen scavenging polymer and at least one vinyl crosslinker. The oxygen scavenging polymer comprises a polymeric backbone, at least two backbone crosslinking functional groups that are carbon-carbon double bonds in the backbone and at least one cyclic organic moiety having from 5 to 9 carbon atoms in its ring, and at least one carbon-carbon double bond in its ring. The vinyl crosslinker comprises at least two functional groups that are capable of reacting with the crosslinking functional groups of the oxygen scavenging polymer. Vinyl crosslinkers that can be used include styrene and methyl acrylate, among others.

    Abstract translation: 所公开的发明涉及一种除氧组合物，其包含至少一种除氧聚合物和至少一种乙烯基交联剂。 氧清除聚合物包含聚合物骨架，至少两个骨架交联官能团，其主链中为碳 - 碳双键，以及至少一个在其环中具有5-9个碳原子的环状有机部分，以及至少一个碳 - 碳双键环。 乙烯基交联剂包含至少两个能够与除氧聚合物的交联官能团反应的官能团。 可以使用的乙烯基交联剂包括苯乙烯和丙烯酸甲酯等。

    Compatible blend systems from ethylene vinyl alcohol and oxygen scavenging polymers
    10.
    发明授权
    Compatible blend systems from ethylene vinyl alcohol and oxygen scavenging polymers 有权
    与乙烯乙烯醇和除氧聚合物相容的混合体系

    公开(公告)号：US06525123B1

    公开(公告)日：2003-02-25

    申请号：US09575094

    申请日：2000-05-19

    Applicant: Hu Yang ,  Ta Yen Ching ,  Gangfeng Cai

    Inventor： Hu Yang ,  Ta Yen Ching ,  Gangfeng Cai

    IPC: C08L2904

    CPC classification number: C08L29/04 ,  C08L23/08 ,  C08L23/0823 ,  C08L67/02 ,  C08L2201/14 ,  C08L2666/18 ,  C08L2666/20 ,  C08L2666/04 ,  C08L2666/02

    Abstract: Herein is disclosed an oxygen barrier composition comprising ethylene/vinyl alcohol copolymer (EVOH), an oxygen scavenging polymer, and a transition metal salt. The composition can be in the form of a physical blend or a cross-linked blend, and can further comprise a compatibilizer, a transesterification catalyst, or both. Also disclosed is a packaging article comprising at least one high oxygen barrier layer comprising the blend of EVOH, the oxygen scavenging polymer, and the transition metal salt. The packaging article can be a single-layer or a multilayer article, and can be flexible or rigid. A multilayer packaging article can further comprise a structural layer or layers, an oxygen barrier layer, an oxygen scavenging layer, an oxygen permeable layer or layers, or an adhesive layer or layers, among others. In addition, herein is disclosed a method of making the blend of EVOH, the oxygen scavenging polymer, and the transition metal salt, comprising providing and blending the materials. The blend can be used in a method of making an oxygen scavenging packaging article.

    Abstract translation: 本文公开了包含乙烯/乙烯醇共聚物（EVOH），除氧聚合物和过渡金属盐的氧阻隔组合物。 组合物可以是物理共混物或交联共混物的形式，并且还可以包含增容剂，酯交换催化剂或二者。 还公开了包含至少一个包含EVOH，除氧聚合物和过渡金属盐的共混物的高氧阻隔层的包装制品。 包装制品可以是单层或多层制品，并且可以是柔性的或刚性的。 多层包装制品还可以包括结构层，氧阻隔层，除氧层，氧可渗透层或层，或粘合剂层或其它层。 此外，本文公开了制备EVOH，除氧聚合物和过渡金属盐的共混物的方法，其包括提供和混合材料。 该共混物可用于制造除氧包装制品的方法。

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