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    Systems, methods and devices for achieving glycemic balance
    1.
    发明授权
    Systems, methods and devices for achieving glycemic balance 有权

    公开(公告)号：US11826163B2

    公开(公告)日：2023-11-28

    申请号：US16918489

    申请日：2020-07-01

    申请人： Hygieia, Inc.

    发明人： Eran Bashan ,  Israel Hodish

    IPC分类号： A61B5/00 ,  A61B5/145 ,  A61M5/172 ,  G16H20/17 ,  G16H20/10 ,  A61M5/142

    CPC分类号： A61B5/4839 ,  A61B5/14532 ,  A61M5/1723 ,  G16H20/10 ,  G16H20/17 ,  A61B5/0002 ,  A61M5/142 ,  A61M2205/50 ,  A61M2205/507 ,  A61M2205/52

    摘要： Systems, methods and/or devices for optimizing a patient's insulin dosage regimen over time, comprising at least a first memory for storing data inputs corresponding at least to one or more components in a patient's present insulin dosage regimen, and data inputs corresponding at least to the patient's blood-glucose-level measurements determined at a plurality of times, and a processor operatively connected to the at least first memory. The processor is programmed at least to determine from the data inputs corresponding to the patient's blood-glucose-level measurements determined at a plurality of times whether and by how much to vary at least one of the one or more components in the patient's present insulin dosage regimen. Also disclosed are systems, methods and/or devices for treating a patient's diabetes by providing treatment guidance, wherein the patient's current glycemic state is determined relative to a desired balance point; and determining from at least one of a plurality of the data corresponding to the patient's blood glucose-level measurements whether and by how much to vary at least one of the one or more components in the patient's present insulin dosage regimen to get closer to the patient's desired balance point; wherein the desired balance point is the patient's lowest blood glucose-level within a predetermined range achievable before increasing the frequency of hypoglycemic events above a predetermined threshold.

    Apparatus for Optimizing A Patient's Insulin Dosage Regimen
    3.
    发明公开
    Apparatus for Optimizing A Patient's Insulin Dosage Regimen 审中-公开

    公开(公告)号：US20240071591A1

    公开(公告)日：2024-02-29

    申请号：US18229420

    申请日：2023-08-02

    申请人： Hygieia, Inc.

    发明人： Eran Bashan ,  Israel Hodish

    IPC分类号： G16H20/17 ,  A61B5/145 ,  A61M5/172 ,  G16H10/00 ,  G16H20/10

    CPC分类号： G16H20/17 ,  A61B5/14532 ,  A61M5/1723 ,  G16H10/00 ,  G16H20/10 ,  A61B5/0002

    摘要： An apparatus for optimizing a patient's insulin dosage regimen over time, comprising: at least a first computer-readable memory for storing data inputs corresponding at least to one or more components in a patient's present insulin dosage regimen and the patient's blood-glucose-level measurements determined at a plurality of times; a processor operatively connected to the at least first computer-readable memory, the processor programmed at least to determine from the data inputs corresponding to the patient's blood-glucose-level measurements determined at a plurality of times whether and by how much to vary at least one of the one or more components of the patient's present insulin dosage regimen in order to maintain the patient's future blood-glucose-level measurements within a predefined range; and a display operative to display information corresponding to at least the patient's present insulin dosage regimen.

    Systems, devices, and methods for alleviating glucotoxicity and restoring pancreatic beta-cell function in advanced diabetes mellitus
    4.
    发明授权
    Systems, devices, and methods for alleviating glucotoxicity and restoring pancreatic beta-cell function in advanced diabetes mellitus 有权

    公开(公告)号：US11723592B2

    公开(公告)日：2023-08-15

    申请号：US16817161

    申请日：2020-03-12

    申请人： Hygieia, Inc.

    发明人： Eran Bashan ,  Israel Hodish

    IPC分类号： A61B5/00 ,  A61M5/172 ,  A61B5/145 ,  G16H20/17 ,  G16H10/40

    CPC分类号： A61B5/4839 ,  A61B5/14532 ,  A61B5/7275 ,  A61M5/1723 ,  G16H10/40 ,  G16H20/17 ,  A61B5/0002 ,  A61B5/4842

    摘要： Systems, methods and/or devices for treating diabetes mellitus by alleviating glucotoxicity and restoring pancreatic beta-cell function, comprising at least a first memory for storing data inputs corresponding at least to one or more components in a patient's present insulin dosage regimen, and data inputs corresponding at least to the patient's blood-glucose-level measurements determined at a plurality of times, and a processor operatively connected to the at least first memory. The processor is programmed at least to determine from the data inputs corresponding to the patient's blood-glucose-level measurements determined at a plurality of times whether and by how much to vary at least one of the components of the patient's present insulin dosage regimen. Also disclosed are systems, methods, and/or devices for alleviating glucotoxicity and restoring pancreatic beta-cell function, comprising establishing the patient's current glycemic state relative to a desired glycemic range and determining from at least one of a plurality of the data corresponding to the patient's blood glucose-level measurements whether and by how much to adjust at least one of the components in the patient's present insulin dosage regimen.

    Apparatus for optimizing a patient's insulin dosage regimen
    5.
    发明授权
    Apparatus for optimizing a patient's insulin dosage regimen 有权

    公开(公告)号：US10335546B2

    公开(公告)日：2019-07-02

    申请号：US14067479

    申请日：2013-10-30

    申请人： Hygieia, Inc.

    发明人： Eran Bashan ,  Israel Hodish

    IPC分类号： G01N33/48 ,  A61M5/172 ,  A61B5/145 ,  G06F19/00 ,  A61B5/00 ,  A61M5/142

    摘要： An apparatus for optimizing a patient's insulin dosage regimen over time, comprising: at least a first computer-readable memory for storing data inputs corresponding at least to one or more components in a patient's present insulin dosage regimen and the patient's blood-glucose-level measurements determined at a plurality of times; a processor operatively connected to the at least first computer-readable memory, the processor programmed at least to determine from the data inputs corresponding to the patient's blood-glucose-level measurements determined at a plurality of times whether and by how much to vary at least one of the one or more components of the patient's present insulin dosage regimen in order to maintain the patient's future blood-glucose-level measurements within a predefined range; and a display operative to display information corresponding to at least the patient's present insulin dosage regimen.

    Systems, Methods and Devices for Achieving Glycemic Balance
    7.
    发明公开
    Systems, Methods and Devices for Achieving Glycemic Balance 审中-公开

    公开(公告)号：US20240156400A1

    公开(公告)日：2024-05-16

    申请号：US18488675

    申请日：2023-10-17

    申请人： Hygieia, Inc.

    发明人： Eran Bashan ,  Israel Hodish

    IPC分类号： A61B5/00 ,  A61B5/145 ,  A61M5/172 ,  G16H20/10 ,  G16H20/17

    CPC分类号： A61B5/4839 ,  A61B5/14532 ,  A61M5/1723 ,  G16H20/10 ,  G16H20/17 ,  A61B5/0002 ,  A61M5/142

    摘要： Systems, methods and/or devices for optimizing a patient's insulin dosage regimen over time, comprising at least a first memory for storing data inputs corresponding at least to one or more components in a patient's present insulin dosage regimen, and data inputs corresponding at least to the patient's blood-glucose-level measurements determined at a plurality of times, and a processor operatively connected to the at least first memory. The processor is programmed at least to determine from the data inputs corresponding to the patient's blood-glucose-level measurements determined at a plurality of times whether and by how much to vary at least one of the one or more components in the patient's present insulin dosage regimen. Also disclosed are systems, methods and/or devices for treating a patient's diabetes by providing treatment guidance, wherein the patient's current glycemic state is determined relative to a desired balance point; and determining from at least one of a plurality of the data corresponding to the patient's blood glucose-level measurements whether and by how much to vary at least one of the one or more components in the patient's present insulin dosage regimen to get closer to the patient's desired balance point; wherein the desired balance point is the patient's lowest blood glucose-level within a predetermined range achievable before increasing the frequency of hypoglycemic events above a predetermined threshold.

    Systems, methods and devices for achieving glycemic balance
    9.
    发明授权
    Systems, methods and devices for achieving glycemic balance 有权

    公开(公告)号：US10736562B2

    公开(公告)日：2020-08-11

    申请号：US14946259

    申请日：2015-11-19

    申请人： Hygieia, Inc.

    发明人： Eran Bashan ,  Israel Hodish

    IPC分类号： A61B5/00 ,  A61B5/145 ,  A61M5/172 ,  G06F19/00 ,  A61M5/142

    摘要： Systems, methods and/or devices for optimizing a patient's insulin dosage regimen over time, comprising at least a first memory for storing data inputs corresponding at least to one or more components in a patient's present insulin dosage regimen, and data inputs corresponding at least to the patient's blood-glucose-level measurements determined at a plurality of times, and a processor operatively connected to the at least first memory. The processor is programmed at least to determine from the data inputs corresponding to the patient's blood-glucose-level measurements determined at a plurality of times whether and by how much to vary at least one of the one or more components in the patient's present insulin dosage regimen. Also disclosed are systems, methods and/or devices for treating a patient's diabetes by providing treatment guidance, wherein the patient's current glycemic state is determined relative to a desired balance point; and determining from at least one of a plurality of the data corresponding to the patient's blood glucose-level measurements whether and by how much to vary at least one of the one or more components in the patient's present insulin dosage regimen to get closer to the patient's desired balance point; wherein the desired balance point is the patient's lowest blood glucose-level within a predetermined range achievable before increasing the frequency of hypoglycemic events above a predetermined threshold.

    System for optimizing a patient's insulin dosage regimen
    10.
    发明授权
    System for optimizing a patient's insulin dosage regimen 有权

    公开(公告)号：US10272198B2

    公开(公告)日：2019-04-30

    申请号：US13868612

    申请日：2013-04-23

    申请人： Hygieia, Inc.

    发明人： Eran Bashan ,  Israel Hodish

    IPC分类号： G01N33/48 ,  A61M5/172 ,  A61B5/145 ,  G06F19/00 ,  A61B5/00 ,  A61M5/142

    摘要： A system for optimizing a patient's insulin dosage regimen over time, comprising at least a first memory for storing data inputs corresponding at least to one or more components in a patient's present insulin dosage regimen, and data inputs corresponding at least to the patient's blood-glucose-level measurements determined at a plurality of times, and a processor operatively connected to the at least first memory. The processor is programmed at least to determine from the data inputs corresponding to the patient's blood-glucose-level measurements determined at a plurality of times whether and by how much to vary at least one of the one or more components in the patient's present insulin dosage regimen in order to maintain the patient's future blood-glucose-level measurements within a predefined range.