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公开(公告)号:US5741487A
公开(公告)日:1998-04-21
申请号:US806626
申请日:1997-02-26
申请人: Yoshio Asai , Motoyasu Ohdera , Hiromitsu Kigawa , Isao Shimotsuura , Yoshiko Yokobori , Masanori Hirano , Koji Shibuya
发明人: Yoshio Asai , Motoyasu Ohdera , Hiromitsu Kigawa , Isao Shimotsuura , Yoshiko Yokobori , Masanori Hirano , Koji Shibuya
IPC分类号: A61K8/00 , A61K8/66 , A61K38/46 , A61K38/47 , A61P1/02 , A61Q11/00 , A61Q11/02 , C12N1/20 , C12N9/24 , C12R1/07
CPC分类号: A61Q11/02 , A61K8/66 , A61Q11/00 , C12N9/2402 , C12Y302/01084
摘要: An oral composition contains mutanase prepared from a culture which is obtained by cultivating a mutanase-producing microorganism belonging to the genus Bacillus having negative protease producibility. The oral composition is effective for suppressing dental plaque formation while the mutanase possesses commercially acceptable stability in the oral composition.
摘要翻译: 口服组合物含有由通过培养属于具有阴性蛋白酶生产能力的芽孢杆菌属的产生葡聚糖酶的微生物获得的培养物制备的齿斑葡聚糖酶。 口腔组合物对于抑制牙菌斑形成是有效的,而斑驳葡聚糖酶在口腔组合物中具有商业上可接受的稳定性。