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1.发明授权Bioactive peptides derived from the proteins of egg white by means of enzymatic hydrolysis 有权通过酶水解衍生自蛋清蛋白质的生物活性肽公开(公告)号：US08227207B2
公开(公告)日：2012-07-24
申请号：US11343263
申请日：2006-01-30
申请人： Marta Miguel Castro , Rosina Lopez-Alonso Fandiño , Maria Isidra Recio Sanchez , Maria Mercedes Ramos Gonzalez , Amaya Aleixandre De Artiñano
发明人： Marta Miguel Castro , Rosina Lopez-Alonso Fandiño , Maria Isidra Recio Sanchez , Maria Mercedes Ramos Gonzalez , Amaya Aleixandre De Artiñano
CPC分类号： C07K14/8103 , A23J3/341 , A23L33/18 , A61K38/012 , C07K14/465 , C12P21/06
摘要： The invention relates to the production of ovoproducts containing bioactive peptides from the egg white subjected to enzymatic treatment. Said peptides have an inhibiting activity of the angiotensin converting enzyme (ACE inhibiting activity) in vitro and/or anti-hypertensive activity in rats and/or antioxidant activity. Said ovoproducts, complete hydrolyzates, the fractions thereof with low molecular weight or their constituent peptides could be used as therapeutic substances with ACE inhibiting activity and/or anti-hypertensive activity and/or anti-oxidant activity, either as functional food products, food additives or ingredients or pharmaceutical products for the treatment and/or prevention of hypertension in all its forms in humans or animals and for the treatment and/or prevention of any disorder associated with hypertension in humans or animals.
摘要翻译： 本发明涉及产生含有经过酶处理的蛋白的生物活性肽的产卵。 所述肽在体外和/或抗高血压活性和/或抗氧化活性中具有血管紧张素转换酶（ACE抑制活性）的抑制活性。 所述产物，完全水解产物，低分子量的级分或其组成肽可用作具有ACE抑制活性和/或抗高血压活性和/或抗氧化活性的治疗物质，作为功能性食品，食品添加剂 或用于治疗和/或预防人或动物中所有形式的高血压以及用于治疗和/或预防与人或动物中的高血压相关的任何紊乱的成分或药物产品。
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2.发明申请Bioactive peptides identified in enzymatic hydrolyzates of milk caseins and method of obtaining same 有权在乳酪蛋白的酶水解产物中鉴定的生物活性肽及其获得方法公开(公告)号：US20100048464A1
公开(公告)日：2010-02-25
申请号：US11921797
申请日：2006-06-08
申请人： Isidra Recio Sanchez , Ana Quiros Del Bosque , Blanca Hernandez Ledesma , José Angel Gomez Ruiz , Marta Miguel Castro , Maria Lourdes Amigo Garrido , Ivan Lopez Exposito , Maria Mercedes Ramos Gonzalez , Amaya Aleixandre De Artiñano , Mar Contreras Gómez
发明人： Isidra Recio Sanchez , Ana Quiros Del Bosque , Blanca Hernandez Ledesma , José Angel Gomez Ruiz , Marta Miguel Castro , Maria Lourdes Amigo Garrido , Ivan Lopez Exposito , Maria Mercedes Ramos Gonzalez , Amaya Aleixandre De Artiñano , Mar Contreras Gómez
IPC分类号： A61K38/16 , C07K14/00 , C07K7/00 , C12P21/02 , A61K38/08 , A61K38/10 , A61K38/07 , A61K38/06 , A23L1/305
CPC分类号： C07K14/4732 , A23J3/344 , A23L33/18 , A61K38/00 , C07K5/101 , C12P21/06 , Y02A50/473
摘要： The invention relates to the production of bioactive products that are derived from milk proteins for the production of bioactive milk products derived from milk proteins, particularly caseins. The 16 inventive peptides can be obtained chemically, biotechnologically or by means of enzymatic treatment from proteins containing same and give rise to peptides with an antimicrobial activity, an in vitro angiotensin converter inhibitor activity and/or antihypertensive activity and/or antioxidant activity. Said nutraceutical products are suitable for use in the food and pharmaceutical industries, both in the form of a hydrolyzate or bioactive peptides.
摘要翻译： 本发明涉及从乳蛋白衍生的生物活性产物的生产，用于生产衍生自乳蛋白质，特别是酪蛋白的生物活性乳制品。 16种本发明的肽可以通过化学，生物技术或通过从含有其的蛋白质的酶处理获得并产生具有抗微生物活性的肽，体外血管紧张素转换酶抑制剂活性和/或抗高血压活性和/或抗氧化活性来获得。 所述营养产品适用于食品和制药工业，其形式为水解产物或生物活性肽。
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3.发明授权Bioactive peptides identified in enzymatic hydrolyzates of milk caseins and method of obtaining same 有权在乳酪蛋白的酶水解产物中鉴定的生物活性肽及其获得方法公开(公告)号：US08354502B2
公开(公告)日：2013-01-15
申请号：US11921797
申请日：2006-06-08
申请人： Isidra Recio Sanchez , Ana Quiros Del Bosque , Blanca Hernandez Ledesma , JoséAngel Gomez Ruiz , Marta Miguel Castro , Maria Lourdes Amigo Garrido , Ivan Lopez Exposito , Maria Mercedes Ramos Gonzalez , Amaya Aleixandre De Artiñano , Mar Contreras Gómez
发明人： Isidra Recio Sanchez , Ana Quiros Del Bosque , Blanca Hernandez Ledesma , JoséAngel Gomez Ruiz , Marta Miguel Castro , Maria Lourdes Amigo Garrido , Ivan Lopez Exposito , Maria Mercedes Ramos Gonzalez , Amaya Aleixandre De Artiñano , Mar Contreras Gómez
IPC分类号： A61K38/16
CPC分类号： C07K14/4732 , A23J3/344 , A23L33/18 , A61K38/00 , C07K5/101 , C12P21/06 , Y02A50/473
摘要： The invention relates to the production of bioactive products that are derived from milk proteins for the production of bioactive milk products derived from milk proteins, particularly caseins. The 16 inventive peptides can be obtained chemically, biotechnologically or by means of enzymatic treatment from proteins containing same and give rise to peptides with an antimicrobial activity, an in vitro angiotensin converter inhibitor activity and/or antihypertensive activity and/or antioxidant activity. Said nutraceutical products are suitable for use in the food and pharmaceutical industries, both in the form of a hydrolyzate or bioactive peptides.
摘要翻译： 本发明涉及从乳蛋白衍生的生物活性产物的生产，用于生产衍生自乳蛋白质，特别是酪蛋白的生物活性乳制品。 16种本发明的肽可以通过化学，生物技术或通过从含有其的蛋白质的酶处理获得并产生具有抗微生物活性的肽，体外血管紧张素转换酶抑制剂活性和/或抗高血压活性和/或抗氧化活性来获得。 所述营养产品适用于食品和制药工业，其形式为水解产物或生物活性肽。
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