公开(公告)号：US07691987B2

公开(公告)日：2010-04-06

申请号：US10562324

申请日：2004-06-30

申请人： Gisela Greif ,  Ralf Hosse ,  Jürgen Krücken ,  Frank Wunderlich

发明人： Gisela Greif ,  Ralf Hosse ,  Jürgen Krücken ,  Frank Wunderlich

IPC分类号： C07H21/04 ,  C07H21/02 ,  C12N15/63 ,  C12N15/85 ,  C12N15/86 ,  C12N1/20 ,  C12N15/00 ,  C12Q1/68

CPC分类号： C07K16/20 ,  A61K39/012 ,  A61K2039/505 ,  A61K2039/53 ,  C07K14/455

摘要： The invention relates to a novel oocyst sporocyst protein (EtOs22) belonging to the parasite of the species Eimeria tenella and to the polynucleotide encoding this protein, to vectors which contain this polynucleotide, to cells which are transformed with these vectors, to antibodies which are directed against the protein, to vaccines which comprise the polynucleotide, the protein, or fragments thereof, the abovementioned vectors or antibodies directed against the protein, and to the use of polynucleotide or of polypeptide for finding active compounds for treating an infection with Eimeria and active compounds which are suitable for the therapy of an infection with Eimeria.

摘要翻译： 本发明涉及属于艾美球虫种类的寄生虫和编码该蛋白质的多核苷酸的新型卵囊孢子蛋白（EtOs22）与含有该多核苷酸的载体对于被这些载体转化的细胞与被定向的抗体 针对蛋白质的疫苗，涉及包含多核苷酸，蛋白质或其片段的疫苗，针对蛋白质的上述载体或抗体，以及使用多核苷酸或多肽寻找用于治疗艾美球虫感染和活性化合物的活性化合物 其适用于艾美球虫感染的治疗。