公开(公告)号：US06949264B1

公开(公告)日：2005-09-27

申请号：US09621780

申请日：2000-07-21

申请人： Gordon N. McGrew ,  David G. Barkalow ,  Sonya S. Johnson ,  David W. Record ,  Mansukh M. Patel ,  Jack D. Nimz ,  Steven E. Zibell ,  Robert J. Yatka ,  Michael J. Greenberg ,  Rebecca A. Aumann ,  Daniel J. Zyck ,  Daniel J. Sitler ,  Jeffrey S. Hook ,  James R. Maxwell ,  Michael A. Reed ,  Victor V. Gudas ,  Philip G. Schnell ,  Henry T. Tyrpin ,  Michael P. Russell ,  David L. Witkewitz ,  Joo H. Song ,  Donald J. Townsend ,  Donald A. Seielstad ,  Ronald L. Ream ,  Christine L. Corriveau ,  William J. Wokas ,  Thomas M. Tongue

发明人： Gordon N. McGrew ,  David G. Barkalow ,  Sonya S. Johnson ,  David W. Record ,  Mansukh M. Patel ,  Jack D. Nimz ,  Steven E. Zibell ,  Robert J. Yatka ,  Michael J. Greenberg ,  Rebecca A. Aumann ,  Daniel J. Zyck ,  Daniel J. Sitler ,  Jeffrey S. Hook ,  James R. Maxwell ,  Michael A. Reed ,  Victor V. Gudas ,  Philip G. Schnell ,  Henry T. Tyrpin ,  Michael P. Russell ,  David L. Witkewitz ,  Joo H. Song ,  Donald J. Townsend ,  Donald A. Seielstad ,  Ronald L. Ream ,  Christine L. Corriveau ,  William J. Wokas ,  Thomas M. Tongue

IPC分类号： A23G4/06 ,  A23L1/00 ,  A61K9/00 ,  A61K9/68 ,  A23G3/30

CPC分类号： A61K9/0058 ,  A23G4/06 ,  A23P10/30 ,  A61K9/0056

摘要： A method for producing a chewing gum with a controlled release active agent, as well as the chewing gum so produced, is obtained by physically modifying the release properties of the active agent, such as a nutraceutical or nutritional supplement, by coating and drying. The active agent is coated by encapsulation, partially coated by agglomeration, entrapped by absorption, or treated by multiple steps of encapsulation, agglomeration, and absorption. The coated active agent is preferably then co-dried and particle sized to produce a release-modified active agent for use in chewing gum. The active agent may also be used in a coating on a chewing gum product, as part of a rolling compound applied to the chewing gum product, or as a part of the liquid in a liquid-center chewing gum product.

摘要翻译： 通过涂覆和干燥来物理改变活性剂如营养补充剂或营养补充剂的释放性质，获得了具有控制释放活性剂以及如此生产的口香糖的口香糖的生产方法。 活性剂通过包封进行包衣，通过附聚部分包被，通过吸收包埋，或通过包封，附聚和吸收的多个步骤进行处理。 涂覆的活性剂优选然后共干燥并调整粒径以产生用于口香糖的释放改性活性剂。 活性剂也可以用作口香糖产品上的涂层，作为施用于口香糖产品的滚动化合物的一部分，或作为液体中心口香糖产品中的液体的一部分使用。