公开(公告)号：US4748186A

公开(公告)日：1988-05-31

申请号：US880421

申请日：1986-06-30

申请人： Thomas G. Cullen ,  Anthony J. Martinez ,  Jacob J. Vukich

发明人： Thomas G. Cullen ,  Anthony J. Martinez ,  Jacob J. Vukich

IPC分类号： A01N47/42 ,  A01N55/00 ,  A01N57/12 ,  C07D213/75 ,  C07D261/08 ,  C07D263/48 ,  C07D277/18 ,  C07D277/38 ,  C07D277/48 ,  C07D277/82 ,  C07D285/12 ,  C07D285/135 ,  C07D307/79 ,  C07D333/18 ,  C07D333/28 ,  C07D413/04 ,  C07F7/08 ,  C07F7/18 ,  C07F9/165 ,  C07C119/18 ,  C07C155/08 ,  A01N37/00 ,  A01N47/10

CPC分类号： C07D213/75 ,  A01N47/42 ,  A01N55/00 ,  A01N57/12 ,  C07D261/08 ,  C07D263/48 ,  C07D277/18 ,  C07D277/48 ,  C07D277/82 ,  C07D285/135 ,  C07D307/79 ,  C07D333/18 ,  C07D333/28 ,  C07D413/04 ,  C07F7/0818 ,  C07F7/184 ,  C07F9/1651

摘要： S-trifluorobutenyl thiocarbonic acid esters of the formula ##STR1## and salts thereof, wherein X is R.sup.1 N or S and Y is RS or R.sup.3 R.sup.2 N;wherein R is a metal or a radical selected from alkyl, cycloalkylalkyl, halocycloalkylalkyl, alkenyl, haloalkyl, haloalkenyl, alkynyl, alkoxyalkyl, alkylthioalkyl, alkoxycarbonylalkyl, halophenoxyalkyl, trialkylsilylalkyl, (vinyl)dialkylsilylalkyl, (allyl)dialkylsilylalkyl, 2-chlorothiophene-5-ylmethyl, phenylalkyl, halophenylalkyl, nitrophenylalkyl, haloalkylphenylalkyl, dialkyl-2,3-dihydrobenzofuran-7-yl, [2-methyl-(1,1'-biphenyl)-3-yl]methyl, 3-phenoxybenzyl, phenylthioalkyl, halophenylthioalkyl, dialkylphosphoryl, dialkylthiophosphoryl, dialkylisoxazolylalkyl and thienylisoxazolylalkyl;wherein R.sup.1 is alkyl, cycloalkyl, cyano, dialkyl-2,3-dihydrobenzofuran-7-yl, halophenyl, halophenylalkyl, haloalkoxyphenyl, pyridinyl, halopyridinyl, alkyl-1,3,4-thiadiazolyl, haloalkyl-1,3,4-thiadiazolyl, benzothiazolyl, dialkyloxazolyl or thiazolinyl;wherein R.sup.2 is hydrogen or alkyl; andwherein R.sup.3 is alkyl, haloalkyl, cycloalkyl, cycloalkylalkyl, dialkylaminoalkyl, dialkyl-2-oxazolyl, 2-thiazolinyl, 2-benzothiazolyl, 4-phenyl-2-thiazolyl, alkyl-1,3,4-thiadiazolyl, haloalkyl-1,3,4-thiadiazolyl, pyridinyl, halopyridinyl, phenyl, halophenyl, halophenylalkyl, haloalkoxyphenyl, or dialkyl-2,3-dihydrobenzofuran-7-yl;provided that:when X is S, Y is R.sup.3 R.sup.2 N,when X is R.sup.1 N, Y is RS, R.sup.1 is other than alkyl and R is other than haloalkenyl; andwhen X is R.sup.1 N where R.sup.1 is CN and Y is RS, R is other than alkali metal.The compounds exhibit nematicidal and anthelmintic activity and are useful in agriculture and veterinary practice.

摘要翻译： 其中X为R 1 N或S且Y为RS或R 3 R 2 N; 其中R是选自烷基，环烷基烷基，卤代环烷基，烯基，卤代烷基，卤代烯基，炔基，烷氧基烷基，烷硫基烷基，烷氧基羰基烷基，卤代苯氧基烷基，三烷基甲硅烷基烷基，（乙烯基）二烷基甲硅烷基烷基，（烯丙基）二烷基甲硅烷基烷基，2-氯噻吩-5- 苯基烷基，卤代苯基烷基，硝基苯基烷基，卤代烷基苯基烷基，二烷基-2,3-二氢苯并呋喃-7-基，[2-甲基 - （1,1'-联苯基）-3-基]甲基，3-苯氧基苄基，苯硫基烷基，卤代苯硫基烷基， 二烷基磷酰基，二烷基硫代磷酰基，二烷基异恶唑烷基和噻吩并恶唑基烷基; 其中R1是烷基，环烷基，氰基，二烷基-2,3-二氢苯并呋喃-7-基，卤代苯基，卤代苯基烷基，卤代烷氧基苯基，吡啶基，卤代吡啶基，烷基-1,3,4-噻二唑基，卤代烷基-1,3,4-噻二唑基 ，苯并噻唑基，二烷基恶唑基或噻唑啉基; 其中R2是氢或烷基; 其中R 3是烷基，卤代烷基，环烷基烷基，二烷基氨基烷基，二烷基-2-恶唑基，2-噻唑啉基，2-苯并噻唑基，4-苯基-2-噻唑基，烷基-1,3,4-噻二唑基，卤代烷基-1， 吡啶基，卤代吡啶基，苯基，卤代苯基，卤代苯基烷基，卤代烷氧基苯基或二烷基-2,3-二氢苯并呋喃-7-基; 条件是：当X是S时，Y是R 3 R 2 N，当X是R 1 N时，Y是RS，R 1不是烷基，R不是卤代烯基; 当X是R1N，其中R1是CN且Y是RS时，R不是碱金属。 这些化合物显示杀线虫和驱虫活性，可用于农业和兽医实践。