公开(公告)号：US20070004645A1

公开(公告)日：2007-01-04

申请号：US11391391

申请日：2006-03-29

申请人： Surrinder Koul ,  Jawahir Koul ,  Subhash Taneja ,  Pankaj Gupta ,  Inshad Khan ,  Zahid Mirza ,  Ashwani Kumar ,  Rakesh Johri ,  Monika Pandita ,  Anita Khosa ,  Ashok Tikoo ,  Subhash Sharma ,  Vijeshwar Verma ,  Ghulam Qazi

发明人： Surrinder Koul ,  Jawahir Koul ,  Subhash Taneja ,  Pankaj Gupta ,  Inshad Khan ,  Zahid Mirza ,  Ashwani Kumar ,  Rakesh Johri ,  Monika Pandita ,  Anita Khosa ,  Ashok Tikoo ,  Subhash Sharma ,  Vijeshwar Verma ,  Ghulam Qazi

IPC分类号： A61K38/04 ,  A61K31/495 ,  A61K31/445 ,  A61K31/401 ,  C07K5/04

CPC分类号： C07D211/46 ,  A61K31/351 ,  A61K31/445 ,  A61K31/4525 ,  A61K31/453 ,  A61K31/496 ,  A61K31/7036 ,  C07D295/108 ,  C07D311/58 ,  C07D317/60 ,  C07D319/16 ,  C07D319/18 ,  Y02A50/473 ,  Y02A50/481

摘要： The present invention relates to an aromatic substituted pentadienoic acid amides and there use in combination of specific amounts of aromatic amides i.e. 4-alkyl-5-(substituted phenyl)-2(E),4(E)-pentadienoic acid amides, its geometrical isomers or their dihydro or tetrahydro derivatives and an anti-infective drug useful in potentiating the bioefficacy of antiinfective drug. The combination of the present invention is useful in the treatment of certain infections and disease at lower concentration of anti-infectives necessary to inhibit the growth of microbial strains and may also find applications in reducing the resistance in microorganisms.

摘要翻译： 本发明涉及芳族取代的戊二烯酸酰胺，并且其中使用特定量的芳族酰胺，即4-烷基-5-（取代的苯基）-2（E），4（E） - 戊二烯酸酰胺，其几何形状 异构体或其二氢或四氢衍生物和用于增强抗感染药物生物功效的抗感染药物。 本发明的组合可用于治疗抑制微生物菌株生长所必需的较低浓度抗感染剂的某些感染和疾病，并且还可用于降低微生物的抗性。

公开(公告)号：US20060094874A1

公开(公告)日：2006-05-04

申请号：US11300295

申请日：2005-12-15

申请人： Subhash Taneja ,  Surrinder Koul ,  Jawahir Koul ,  Beenu Moza ,  Sukhdev Handa

发明人： Subhash Taneja ,  Surrinder Koul ,  Jawahir Koul ,  Beenu Moza ,  Sukhdev Handa

IPC分类号： C07D413/02 ,  C07D295/08 ,  C07D265/32

CPC分类号： C07D295/185 ,  A23L27/205 ,  C07D311/58 ,  C07D319/18

摘要： The present invention relates to novel compounds possessing specific hot, pungent and spicy taste when subjected to direct pungency evaluation, which may be useful as food additives and anti-oxidants, however the said compounds do not add to any nutritional value but the synthesised compounds can possess useful pharmacological properties which is expected to find application in new test models for the development of anti-inflammatory drugs, bioavailability enhancers and for the study of hepatic drug metabolising mechanism; also relates to a process for preparing the said compounds.