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1.6-Substituted pyridoindolone derivatives, production and therapeutic use thereof 失效
标题翻译: 6-取代的吡啶并吲哚酮衍生物,其制备和治疗用途公开(公告)号:US20070129365A1
公开(公告)日:2007-06-07
申请号:US11582769
申请日:2006-10-18
申请人: Bernard Bourrie , Pierre Casellas , Paola Ciapetti , Jean-Marie Deroco , Samir Jegham , Yvette Muneaux , Camille-Georges Wermuth
发明人: Bernard Bourrie , Pierre Casellas , Paola Ciapetti , Jean-Marie Deroco , Samir Jegham , Yvette Muneaux , Camille-Georges Wermuth
IPC分类号: A61K31/5377 , A61K31/4745 , C07D471/02
CPC分类号: C07D471/04
摘要: Compounds of formula: and pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein R1, R2, R3, R4, and R5, have the meanings given in the description; pharmaceutical compositions comprising said compounds; and processes for preparing said compounds and methods of use thereof.
摘要翻译: 其中R 1,R 2,R 3,R 3,R 3, 4 SUB>和R 5 5具有在说明书中给出的含义; 包含所述化合物的药物组合物; 以及制备所述化合物的方法及其使用方法。
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2.6-heteroarylpyridoindolone derivatives, their preparation and therapeutic use thereof 失效
标题翻译: 6-杂芳基吡啶并吲哚酮衍生物,其制备和治疗用途公开(公告)号:US08063061B2
公开(公告)日:2011-11-22
申请号:US12100079
申请日:2008-04-09
申请人: Yvette Muneaux , Samir Jegham , Bernard Bourrie , Pierre Casellas , Paola Ciapetti , Jean-Marie Deroco , Camille-Georges Wermuth
发明人: Yvette Muneaux , Samir Jegham , Bernard Bourrie , Pierre Casellas , Paola Ciapetti , Jean-Marie Deroco , Camille-Georges Wermuth
IPC分类号: A61K31/44 , C07D471/04
CPC分类号: C07D471/04
摘要: The disclosure relates to compounds of formula (I): wherein R1, R2, R3, R4, are R5 are as defined in the disclosure; their preparation method, compositions containing the same and therapeutic use thereof.
摘要翻译: 本公开涉及式(I)的化合物:其中R1,R2,R3,R4是R5如本公开中所定义; 它们的制备方法,含有其的组合物和治疗用途。
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3.6-substituted pyridoindolone derivatives, production and therapeutic use thereof 失效
标题翻译: 6-取代的吡啶并吲哚酮衍生物,其制备和治疗用途公开(公告)号:US07812165B2
公开(公告)日:2010-10-12
申请号:US11582769
申请日:2006-10-18
申请人: Bernard Bourrie , Pierre Casellas , Paola Ciapetti , Jean-Marie Deroco , Samir Jegham , Yvette Muneaux , Camille-Georges Wermuth
发明人: Bernard Bourrie , Pierre Casellas , Paola Ciapetti , Jean-Marie Deroco , Samir Jegham , Yvette Muneaux , Camille-Georges Wermuth
IPC分类号: C07D571/02 , A61K31/4745
CPC分类号: C07D471/04
摘要: Compounds of formula: and pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein R1, R2, R3, R4, and R5, have the meanings given in the description; pharmaceutical compositions comprising said compounds; and processes for preparing said compounds and methods of use thereof.
摘要翻译: 式的化合物及其药学上可接受的盐,水合物和溶剂化物,其中R1,R2,R3,R4和R5具有说明书中给出的含义; 包含所述化合物的药物组合物; 以及制备所述化合物的方法及其使用方法。
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4.Use of a substance which binds to the peripheral benzodiazepine receptor in the treatment of cutaneous stress 审中-公开
标题翻译: 在治疗皮肤压力时使用结合周边苯二氮卓受体的物质公开(公告)号:US20050090489A1
公开(公告)日:2005-04-28
申请号:US10898793
申请日:2004-07-26
申请人: Pierre Casellas , Jean-Marie Deroco
发明人: Pierre Casellas , Jean-Marie Deroco
IPC分类号: A61K8/00 , C07D243/24 , A01N63/02 , A61K8/30 , A61K8/36 , A61K8/365 , A61K8/49 , A61K31/19 , A61K31/203 , A61K31/551 , A61K31/5513 , A61K31/74 , A61K35/00 , A61K45/00 , A61P17/00 , A61P17/04 , A61P17/06 , A61P31/22 , A61P37/00 , A61P39/06 , A61Q17/04 , A61Q19/00 , A61Q19/08 , C12N1/20 , C12P1/00
CPC分类号: A61K31/5513 , A61K8/494 , A61K31/19 , A61K31/203 , A61K31/74 , A61K2800/70 , A61Q17/04 , A61Q19/00 , A61Q19/08 , Y10S435/803 , Y10S435/886 , Y10S514/828 , Y10S514/947
摘要: A composition containing a peripheral benzodiazepine receptor ligand for topical use in the treatment of cutaneous stress.
摘要翻译: 含有用于局部用于治疗皮肤应激的外周苯并二氮杂受体配体的组合物。
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