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    Voice and text transmission system
    3.
    发明授权
    Voice and text transmission system 有权
    语音和文本传输系统

    公开(公告)号：US06504910B1

    公开(公告)日：2003-01-07

    申请号：US09876340

    申请日：2001-06-07

    申请人： Robert Engelke ,  Kevin Colwell ,  Troy Vitek ,  Jeffrey Havens ,  Kurt Grittner ,  Dean Hofstetter ,  Mathew McCulley

    发明人： Robert Engelke ,  Kevin Colwell ,  Troy Vitek ,  Jeffrey Havens ,  Kurt Grittner ,  Dean Hofstetter ,  Mathew McCulley

    IPC分类号： H04M1100

    CPC分类号： H04L12/66 ,  H04M3/42391 ,  H04M7/006 ,  H04M2201/40

    摘要： A communication system and format is described for use in assisted telephonic communications, intended to help users who are hearing impaired use the telephone system. A relay connects a hearing user with the assisted user. The relay creates a text message stream containing the words spoken by the hearing user. The relay then combines the digital characters of the text message with packets of digitized voice spoken by the hearing user and sends the combined digital data packets to the station of the assisted user. The station of the assisted user is capable of separating the voice from the text and displaying the text for reading by the assisted user.

    摘要翻译： 描述了用于辅助电话通信中的通信系统和格式，旨在帮助听力受损的用户使用电话系统。 继电器将听力用户与辅助用户连接起来。 继电器创建一个包含听力用户说话的文本消息流。 继电器然后将文本消息的数字字符与听力用户所说出的数字化语音的数据组合，并将组合的数字数据包发送到辅助用户的站。 辅助用户的站能够将语音与文本分离并显示文本以供辅助用户阅读。

    Steroid spirolactonization
    5.
    发明申请
    Steroid spirolactonization 审中-公开
    类固醇spirolactonization

    公开(公告)号：US20050090663A1

    公开(公告)日：2005-04-28

    申请号：US10806081

    申请日：2004-03-22

    申请人： Thaddeus Franczyk ,  Grace Wagner ,  Bruce Pearlman ,  Amphlett Padilla ,  Jeffrey Havens ,  Sonja Mackey ,  Haifeng Wu

    发明人： Thaddeus Franczyk ,  Grace Wagner ,  Bruce Pearlman ,  Amphlett Padilla ,  Jeffrey Havens ,  Sonja Mackey ,  Haifeng Wu

    IPC分类号： C07D307/94 ,  C07J20060101 ,  C07J1/00 ,  C07J9/00 ,  C07J19/00 ,  C07J71/00

    CPC分类号： C07J9/00 ,  C07J71/00

    摘要： A steroid comprising a 17-spirolactone or corresponding open lactone structure is obtained by carbonylation of a 17-alkenyl or 17-alkynyl substrate. A 17-alkenyl intermediate may be prepared by semi-hydrogenation of a 17-alkynyl group. Multiple reaction schemes are disclosed for preparation of a 3-keto-9,11-epoxy-17-spirolactone steroid such as eplerenone. Novel intermediates are also disclosed, as well as steps for forming such novel intermediates, or converting them to further intermediates or products, by semi-hydrogenation, carbonylation, 6,7-dehydrogenation, furylation or other transformations or combinations thereof.

    摘要翻译： 通过羰基化17-烯基或17-炔基底物获得包含17-螺内酯或相应的开放内酯结构的类固醇。 17链烯基中间体可以通过17-炔基的半氢化制备。 公开了多种反应方案用于制备3-酮-9,11-环氧-17-螺内酯类固醇如依普利酮。 还公开了新的中间体，以及通过半氢化，羰基化，6,7-脱氢，呋喃基化或其它转化或其组合形成这种新型中间体或将其转化为其它中间体或产物的步骤。

    Method of synthesizing indolinone compounds
    8.
    发明申请
    Method of synthesizing indolinone compounds 审中-公开
    二氢吲哚酮化合物的合成方法

    公开(公告)号：US20060009510A1

    公开(公告)日：2006-01-12

    申请号：US11174892

    申请日：2005-07-05

    申请人： Jeffrey Havens ,  Rajappa Vaidyanathan

    发明人： Jeffrey Havens ,  Rajappa Vaidyanathan

    IPC分类号： C07D209/36 ,  A61K31/404

    CPC分类号： C07D207/416 ,  C07D403/06

    摘要： Disclosed are methods of preparing pyrrole compounds of formula 14 and indolinone compounds of formula 1 via a synthetic route wherein the amide sidechain on the pyrrole moiety is attached prior to pyrrole formation. The compounds 14 produced by the methods herein are useful in the synthesis of compounds of formula 1, which are useful in the treatment of abnormal cell growth, such as cancer.

    摘要翻译： 公开了通过合成途径制备式14的吡咯化合物和式1的吲哚啉酮化合物的方法，其中吡咯部分上的酰胺侧链在形成吡咯之前连接。 通过本文方法产生的化合物14可用于合成式1化合物，其可用于治疗异常细胞生长，例如癌症。