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公开(公告)号:US09359400B2
公开(公告)日:2016-06-07
申请号:US14329758
申请日:2014-07-11
申请人: Aimee Usera , Zachary Robinson , Jennifer Cobb
发明人: Aimee Usera , Zachary Robinson , Jennifer Cobb
IPC分类号: C07K5/103 , A61K49/00 , A61K47/48 , C07K5/083 , C07K5/062 , C07K1/13 , C07D209/42 , C07K7/02 , C07K5/072 , C07C271/22 , C07C317/28 , A61K38/06 , A61K38/05 , A61K38/07
CPC分类号: C07K5/101 , A61K38/00 , A61K38/05 , A61K38/06 , A61K38/07 , A61K47/6415 , A61K49/0002 , C07C271/22 , C07C317/28 , C07C2602/24 , C07D209/42 , C07D229/02 , C07D257/08 , C07K1/13 , C07K5/06043 , C07K5/06104 , C07K5/0808 , C07K7/02
摘要: The present invention relates to methods and reagents for use in site-selective modification of proteins having lysine residues with functionalized peptides using a chemoenzymatic microbial transglutaminase-mediated reaction. The functionalized proteins may be used for study or therapeutic uses.
摘要翻译: 本发明涉及用于使用化学酶微生物转谷氨酰胺酶介导的反应对具有赖氨酸残基的蛋白质进行位点选择性修饰的功能化肽的方法和试剂。 功能化蛋白质可用于研究或治疗用途。
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公开(公告)号:US07201177B2
公开(公告)日:2007-04-10
申请号:US11111112
申请日:2005-04-21
IPC分类号: E04H15/40
CPC分类号: E04H15/40
摘要: A collapsible tent provides insect protection for infants such as less than a year old while being small and portable enough for use in many public spaces. Excellent ventilation and visibility are provided by mosquito and no-see-um blocking fabric formed into a dome-like shape. Flexible support rods cross one another at the apex of the tent and reside within arch-shaped fabric channels. A detachable or alternatively attached ground barrier completes the enclosure. For storage, the flexible support rods are brought adjacent to one another to form a flat arch-shape with the pair of proximate ends then coiled toward the other pair to form a small circular shape that is readily retained within this compact shape by a carrying pouch. When the tent is erected, the carrying pouch is attachable to the tent to serve as a sunshade. A hanging support inside the tent may be used to suspend infant toys.
摘要翻译: 可折叠帐篷为小于一岁的婴儿提供防虫保护,同时体积小巧便携,可用于许多公共场所。 蚊子和无遮盖织物形成圆顶状,提供良好的通风和视野。 柔性支撑杆在帐篷的顶点处彼此交叉,并且位于拱形织物通道内。 可拆卸或替代地附接的地面屏障完成了外壳。 为了存储,柔性支撑杆彼此相邻以形成平坦的拱形,其中一对近端然后被卷绕成另一对,以形成小的圆形形状,其通过承载袋容易地保持在该紧凑形状内 。 当帐篷竖起时,携带的小袋子可附着在帐篷上,作为遮阳篷。 帐篷内的悬挂支架可用于悬挂婴儿玩具。
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公开(公告)号:US20150017192A1
公开(公告)日:2015-01-15
申请号:US14329758
申请日:2014-07-11
申请人: Aimee Usera , Zachary Robinson , Jennifer Cobb
发明人: Aimee Usera , Zachary Robinson , Jennifer Cobb
CPC分类号: C07K5/101 , A61K38/00 , A61K38/05 , A61K38/06 , A61K38/07 , A61K47/6415 , A61K49/0002 , C07C271/22 , C07C317/28 , C07C2602/24 , C07D209/42 , C07D229/02 , C07D257/08 , C07K1/13 , C07K5/06043 , C07K5/06104 , C07K5/0808 , C07K7/02
摘要: The present invention relates to methods and reagents for use in site-selective modification of proteins having lysine residues with functionalized peptides using a chemoenzymatic microbial transglutaminase-mediated reaction. The functionalized proteins may be used for study or therapeutic uses.
摘要翻译: 本发明涉及用于使用化学酶微生物转谷氨酰胺酶介导的反应对具有赖氨酸残基的蛋白质进行位点选择性修饰的功能化肽的方法和试剂。 功能化蛋白质可用于研究或治疗用途。
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