公开(公告)号：US20070248611A1

公开(公告)日：2007-10-25

申请号：US11670096

申请日：2007-02-01

Applicant: Chia-Yang Lin ,  Arnon Rosenthal ,  Jennifer Stratton

Inventor： Chia-Yang Lin ,  Arnon Rosenthal ,  Jennifer Stratton

IPC: A61K38/00 ,  A61K39/395 ,  A61P3/04

CPC classification number: A61K38/185 ,  A61K2039/505 ,  C07K16/2863 ,  C07K2317/75

Abstract: This invention relates to methods for treating unwanted body weight loss (such as with cachexia and with aging), eating disorders (such as anorexia nervosa), or opioid-induced emesis by peripheral administration of a trkB agonist. The invention also relates to compositions and kits comprising a trkB agonist.

Abstract translation: 本发明涉及治疗不希望的体重减轻的方法（例如恶病质和老化），进食障碍（如神经性厌食症）或通过外周施用trkB激动剂的阿片样物质诱导的呕吐。 本发明还涉及包含trkB激动剂的组合物和试剂盒。

公开(公告)号：US20050209148A1

公开(公告)日：2005-09-22

申请号：US11064309

申请日：2005-02-22

Applicant: Arnon Rosenthal ,  John Lin ,  Jennifer Stratton ,  Robert Klein ,  Jaume Pons

Inventor： Arnon Rosenthal ,  John Lin ,  Jennifer Stratton ,  Robert Klein ,  Jaume Pons

IPC: A61K38/17 ,  A61K38/18

CPC classification number: A61K38/185

Abstract: The invention concerns methods for treating obesity, non-insulin dependent diabetes mellitus, metabolic syndrome, and other related diseases by administering an NT-4/5 polypeptide. The invention also concerns compositions and kits comprising an NT-4/5 polypeptide.

Abstract translation: 本发明涉及通过施用NT-4/5多肽来治疗肥胖症，非胰岛素依赖性糖尿病，代谢综合征和其它相关疾病的方法。 本发明还涉及包含NT-4/5多肽的组合物和试剂盒。