公开(公告)号：US20070151933A1

公开(公告)日：2007-07-05

申请号：US11713449

申请日：2007-03-02

申请人： Philip Coelho ,  Eric Sommer ,  Richard Klosinski ,  Jim Hobbs

发明人： Philip Coelho ,  Eric Sommer ,  Richard Klosinski ,  Jim Hobbs

IPC分类号： B01D21/26

CPC分类号： A61M1/3693 ,  A61M1/0231 ,  A61M1/0272 ,  A61M1/0281 ,  B04B5/0428 ,  B04B2005/0435

摘要： An apparatus and method for collecting whole blood and then separating it into components for subsequent use or storage. A self-contained bag set is used to collect the sample, which may then be placed into a device adapted to fit into a centrifuge for separation of components. Each component is then sequentially extracted according to density, with a sensor present in the device to control the operation of valves directing the collection of each component. Each component may then be separated into its own storage container.

公开(公告)号：US07211191B2

公开(公告)日：2007-05-01

申请号：US10957095

申请日：2004-09-30

申请人： Philip H. Coelho ,  Eric Sommer ,  Richard Klosinski ,  Jim Hobbs

发明人： Philip H. Coelho ,  Eric Sommer ,  Richard Klosinski ,  Jim Hobbs

IPC分类号： B01D24/32 ,  B04B5/02 ,  A61M37/00 ,  B04B5/00

CPC分类号： A61M1/3693 ,  A61M1/0231 ,  A61M1/0272 ,  A61M1/0281 ,  B04B5/0428 ,  B04B2005/0435

摘要： An apparatus and method for collecting whole blood and then separating it into components for subsequent use or storage. A self-contained bag set is used to collect the sample, which may then be placed into a device adapted to fit into a centrifuge for separation of components. Each component is then sequentially extracted according to density, with a sensor present in the device to control the operation of valves directing the collection of each component. Each component may then be separated into its own storage container.

摘要翻译： 一种用于收集全血，然后将其分离成组件以供随后使用或储存的装置和方法。 使用独立的袋组来收集样品，然后可以将样品放置在适于装配到离心机中用于分离组分的装置中。 然后根据密度依次提取每个组分，传感器存在于装置中以控制导向各组分收集的阀的操作。 然后可以将每个组件分离成其自己的存储容器。

公开(公告)号：US20060068369A1

公开(公告)日：2006-03-30

申请号：US10957095

申请日：2004-09-30

申请人： Philip Coelho ,  Eric Sommer ,  Richard Klosinski ,  Jim Hobbs ,  Pablo Rubinstein

发明人： Philip Coelho ,  Eric Sommer ,  Richard Klosinski ,  Jim Hobbs ,  Pablo Rubinstein

IPC分类号： A01N1/02 ,  A01N1/00 ,  A61M31/00

CPC分类号： A61M1/3693 ,  A61M1/0231 ,  A61M1/0272 ,  A61M1/0281 ,  B04B5/0428 ,  B04B2005/0435

摘要： An apparatus and method for collecting whole blood and then separating it into components for subsequent use or storage. A self-contained bag set is used to collect the sample, which may then be placed into a device adapted to fit into a centrifuge for separation of components. Each component is then sequentially extracted according to density, with a sensor present in the device to control the operation of valves directing the collection of each component. Each component may then be separated into its own storage container.

摘要翻译： 一种用于收集全血，然后将其分离成组件以供随后使用或储存的装置和方法。 使用独立的袋组来收集样品，然后可以将样品放置在适于装配到离心机中用于分离组分的装置中。 然后根据密度依次提取每个组分，传感器存在于装置中以控制导向各组分收集的阀的操作。 然后可以将每个组件分离成其自己的存储容器。

公开(公告)号：US20080311651A1

公开(公告)日：2008-12-18

申请号：US11664212

申请日：2005-08-16

申请人： Philip H. Coelho ,  Eric Sommer ,  Richard Klosinski ,  Jim Hobbs ,  Bruce Baker ,  Brian Malone

发明人： Philip H. Coelho ,  Eric Sommer ,  Richard Klosinski ,  Jim Hobbs ,  Bruce Baker ,  Brian Malone

IPC分类号： C12M1/00

CPC分类号： A61M1/3693 ,  A61M1/0231 ,  A61M1/0272 ,  A61M1/0281 ,  B04B5/0428 ,  B04B2005/0435

摘要： An apparatus and method for collecting whole blood and then separating it into components for subsequent use or storage. A self-contained bag set is used to collect the sample, which may then be placed into a device adapted to fit into a centrifuge for separation of components. Each component is then sequentially extracted according to density, with a sensor present in the device to control the operation of valves directing the collection of each component. The sensor may be reading one or more of the following characteristics: infrared, optics, density, weight, radioactive, fluorescence, color, magnetism, ultrasonic, capacitance wherein the characteristic is inherent in the blood and blood component or is an additive. Each component may then be separated into its own storage container. The preferred sensors include optics and weight. Besides blood density separation, the device may contain a solution including cells, proteins, subcellular particles or viruses which may be mixed with affinity media or antibodies prior to separation.

摘要翻译： 一种用于收集全血，然后将其分离成组件以供随后使用或储存的装置和方法。 使用独立的袋组来收集样品，然后可以将样品放置在适于装配到离心机中用于分离组分的装置中。 然后根据密度依次提取每个组分，传感器存在于装置中以控制导向各组分收集的阀的操作。 传感器可以读取以下特征中的一个或多个：红外线，光学，密度，重量，放射性，荧光，颜色，磁性，超声波，电容，其特征是血液和血液成分中固有的或者是添加剂。 然后可以将每个组件分离成其自己的存储容器。 优选的传感器包括光学和重量。 除了血液密度分离之外，该装置可以含有可以在分离前可与亲和介质或抗体混合的细胞，蛋白质，亚细胞颗粒或病毒的溶液。

公开(公告)号：US07241281B2

公开(公告)日：2007-07-10

申请号：US10118291

申请日：2002-04-08

申请人： Philip H. Coelho ,  Eric Sommer ,  Richard Klosinski ,  Jim Hobbs

发明人： Philip H. Coelho ,  Eric Sommer ,  Richard Klosinski ,  Jim Hobbs

IPC分类号： A61B19/00 ,  B04B3/00 ,  B01D21/26 ,  B01D29/11 ,  B04B1/00

CPC分类号： A61M1/3693 ,  A61B5/15003 ,  A61B5/150038 ,  A61B5/150045 ,  A61B5/150366 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/153 ,  A61M1/0209 ,  A61M1/0231 ,  A61M1/029 ,  A61M2202/0462 ,  B01D21/262 ,  B01D21/34 ,  B01D2221/10 ,  B04B5/0428

摘要： An apparatus and method for collecting whole blood and then separating it into components for subsequent use or storage. A self-contained bag set is used to collect the sample, which may then be placed into container adapted to fit into a centrifuge for separation of components. Each component is then sequentially extracted according to density, with a sensor present in the container to control the operation of valves directing the collection of each component. Each component may then be separated into its own storage container.

摘要翻译： 一种用于收集全血，然后将其分离成组件以供随后使用或储存的装置和方法。 使用独立的袋组来收集样品，然后可以将样品放入适合于离心机的容器中以分离组分。 然后根据密度依次提取每个组分，存在于容器中的传感器以控制导向每个组分的收集的阀的操作。 然后可以将每个组件分离成其自己的存储容器。

公开(公告)号：US08066127B2

公开(公告)日：2011-11-29

申请号：US11664212

申请日：2005-08-16

申请人： Philip H. Coelho ,  Eric Sommer ,  Richard Klosinski ,  Jim Hobbs ,  Bruce Baker ,  Brian Malone

发明人： Philip H. Coelho ,  Eric Sommer ,  Richard Klosinski ,  Jim Hobbs ,  Bruce Baker ,  Brian Malone

IPC分类号： B01D24/32 ,  B04B5/02 ,  A61M37/00 ,  B04B5/00

CPC分类号： A61M1/3693 ,  A61M1/0231 ,  A61M1/0272 ,  A61M1/0281 ,  B04B5/0428 ,  B04B2005/0435

摘要： An apparatus and method for collecting whole blood and then separating it into components for subsequent use or storage. A self-contained bag set is used to collect the sample, which may then be placed into a device adapted to fit into a centrifuge for separation of components. Each component is then sequentially extracted according to density, with a sensor present in the device to control the operation of valves directing the collection of each component. The sensor may be reading one or more of the following characteristics: infrared, optics, density, weight, radioactive, fluorescence, color, magnetism, ultrasonic, capacitance wherein the characteristic is inherent in the blood and blood component or is an additive. Each component may then be separated into its own storage container. The preferred sensors include optics and weight. Besides blood density separation, the device may contain a solution including cells, proteins, subcellular particles or viruses which may be mixed with affinity media or antibodies prior to separation.

摘要翻译： 一种用于收集全血，然后将其分离成组件以供随后使用或储存的装置和方法。 使用独立的袋组来收集样品，然后可以将样品放置在适于装配到离心机中用于分离组分的装置中。 然后根据密度依次提取每个组分，传感器存在于装置中以控制导向各组分收集的阀的操作。 传感器可以读取以下特征中的一个或多个：红外线，光学，密度，重量，放射性，荧光，颜色，磁性，超声波，电容，其特征是血液和血液成分中固有的或者是添加剂。 然后可以将每个组件分离成其自己的存储容器。 优选的传感器包括光学和重量。 除了血液密度分离之外，该装置可以含有可以在分离前可与亲和介质或抗体混合的细胞，蛋白质，亚细胞颗粒或病毒的溶液。