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公开(公告)号:US20240216914A1
公开(公告)日:2024-07-04
申请号:US18603030
申请日:2024-03-12
Applicant: Alexandra Ros , Daihyun Kim , Jinghui Luo
Inventor: Alexandra Ros , Daihyun Kim , Jinghui Luo
CPC classification number: B01L3/502715 , B01L3/502753 , B01L3/502761 , B03C5/005 , B03C5/026 , B03C5/028 , B01L3/50273 , B01L2200/0647 , B01L2200/0652 , B01L2300/0816 , B01L2400/0406 , B01L2400/0415 , B01L2400/0424 , B01L2400/086 , B03C2201/26 , G01N2001/4038 , G01N2015/0038
Abstract: Sub-micrometer bioparticles are separated by size in a microfluidic channel utilizing a ratchet migration mechanism. A structure within the microfluidic channel includes an array of micro-posts arranged in laterally shifted rows. Reservoirs are disposed at each end of the microfluidic channel. A biased AC potential is applied across the channel via electrodes immersed into fluid in each of the reservoirs to induce a non-uniform electric field through the microfluidic channel. The applied potential comprises a first waveform with a first frequency that induces electro-kinetic flow of sub-micrometer bioparticles in the microfluidic channel, and an intermittent superimposed second waveform with a higher frequency. The second waveform selectively induces a dielectrophoretic trapping force to selectively impart ratchet migration based on particle size for separating the sub-micrometer bioparticles by size in the microfluidic channel.
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公开(公告)号:US11944967B2
公开(公告)日:2024-04-02
申请号:US17524976
申请日:2021-11-12
Applicant: Alexandra Ros , Daihyun Kim , Jinghui Luo
Inventor: Alexandra Ros , Daihyun Kim , Jinghui Luo
CPC classification number: B01L3/502715 , B01L3/502753 , B01L3/502761 , B03C5/005 , B03C5/026 , B03C5/028 , B01L3/50273 , B01L2200/0647 , B01L2200/0652 , B01L2300/0816 , B01L2400/0406 , B01L2400/0415 , B01L2400/0424 , B01L2400/086 , B03C2201/26 , G01N2001/4038 , G01N2015/0038
Abstract: Sub-micrometer bioparticles are separated by size in a microfluidic channel utilizing a ratchet migration mechanism. A structure within the microfluidic channel includes an array of micro-posts arranged in laterally shifted rows. Reservoirs are disposed at each end of the microfluidic channel. A biased AC potential is applied across the channel via electrodes immersed into fluid in each of the reservoirs to induce a non-uniform electric field through the microfluidic channel. The applied potential comprises a first waveform with a first frequency that induces electro-kinetic flow of sub-micrometer bioparticles in the microfluidic channel, and an intermittent superimposed second waveform with a higher frequency. The second waveform selectively induces a dielectrophoretic trapping force to selectively impart ratchet migration based on particle size for separating the sub-micrometer bioparticles by size in the microfluidic channel.
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公开(公告)号:US06978225B2
公开(公告)日:2005-12-20
申请号:US10913675
申请日:2004-08-06
Applicant: Kevin Retlich , Jinghui Luo , Dave Blair
Inventor: Kevin Retlich , Jinghui Luo , Dave Blair
CPC classification number: H04L63/1408
Abstract: A technique for monitoring operational parameters of networked components includes storing data within each component descriptive of the component. The data is polled by a monitoring station and provides a basis for monitor views compiled in real time. The monitor views provide a view of current levels of parameters controlled or monitored by each device, such as on virtual meters. Historical levels of operational parameters may be presented in virtual strip chart output. Textual descriptions of the components are provided, along with listings of key settings. More detailed data may be accessed by links between the monitor views and other user viewable representations for the system and the specific components.
Abstract translation: 用于监视网络组件的操作参数的技术包括在描述组件的每个组件内存储数据。 数据由监控站进行轮询,并为实时编辑的监视视图提供依据。 监视器视图提供了每个设备控制或监控的参数的当前级别的视图,例如虚拟仪表。 操作参数的历史水平可以在虚拟条形图输出中呈现。 提供了组件的文字描述,以及关键设置的列表。 可以通过监视器视图和系统的其他用户可视表示之间的链接以及特定组件来访问更详细的数据。
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公开(公告)号:US20050021291A1
公开(公告)日:2005-01-27
申请号:US10913675
申请日:2004-08-06
Applicant: Kevin Retlich , Jinghui Luo , Dave Blair
Inventor: Kevin Retlich , Jinghui Luo , Dave Blair
CPC classification number: H04L63/1408
Abstract: A technique for monitoring operational parameters of networked components includes storing data within each component descriptive of the component. The data is polled by a monitoring station and provides a basis for monitor views compiled in real time. The monitor views provide a view of current levels of parameters controlled or monitored by each device, such as on virtual meters. Historical levels of operational parameters may be presented in virtual strip chart output. Textual descriptions of the components are provided, along with listings of key settings. More detailed data may be accessed by links between the monitor views and other user viewable representations for the system and the specific components.
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公开(公告)号:US20220072542A1
公开(公告)日:2022-03-10
申请号:US17524976
申请日:2021-11-12
Applicant: Alexandra Ros , Daihyun Kim , Jinghui Luo
Inventor: Alexandra Ros , Daihyun Kim , Jinghui Luo
Abstract: Sub-micrometer bioparticles are separated by size in a microfluidic channel utilizing a ratchet migration mechanism. A structure within the microfluidic channel includes an array of micro-posts arranged in laterally shifted rows. Reservoirs are disposed at each end of the microfluidic channel. A biased AC potential is applied across the channel via electrodes immersed into fluid in each of the reservoirs to induce a non-uniform electric field through the microfluidic channel. The applied potential comprises a first waveform with a first frequency that induces electro-kinetic flow of sub-micrometer bioparticles in the microfluidic channel, and an intermittent superimposed second waveform with a higher frequency. The second waveform selectively induces a dielectrophoretic trapping force to selectively impart ratchet migration based on particle size for separating the sub-micrometer bioparticles by size in the microfluidic channel.
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公开(公告)号:US11173487B2
公开(公告)日:2021-11-16
申请号:US16226165
申请日:2018-12-19
Applicant: Alexandra Ros , Daihyun Kim , Jinghui Luo
Inventor: Alexandra Ros , Daihyun Kim , Jinghui Luo
Abstract: Sub-micrometer bioparticles are separated by size in a microfluidic channel utilizing a ratchet migration mechanism. A structure within the microfluidic channel includes an array of micro-posts arranged in laterally shifted rows. Reservoirs are disposed at each end of the microfluidic channel. A biased AC potential is applied across the channel via electrodes immersed into fluid in each of the reservoirs to induce a non-uniform electric field through the microfluidic channel. The applied potential comprises a first waveform with a first frequency that induces electro-kinetic flow of sub-micrometer bioparticles in the microfluidic channel, and an intermittent superimposed second waveform with a higher frequency. The second waveform selectively induces a dielectrophoretic trapping force to selectively impart ratchet migration based on particle size for separating the sub-micrometer bioparticles by size in the microfluidic channel.
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公开(公告)号:US20190224689A1
公开(公告)日:2019-07-25
申请号:US16317481
申请日:2017-07-12
Applicant: Alexandra Ros , Daihyun Kim , Jinghui Luo , Mian Yang
Inventor: Alexandra Ros , Daihyun Kim , Jinghui Luo , Mian Yang
IPC: B03C5/00 , G01N27/447 , B03C5/02
Abstract: Methods and systems are described for tuning an electrical field gradient for insulator-based di electrophoresis (iDEP). A fluidic layer defines a fluidic channel adjacent to a substrate. A deformable membrane is positioned adjacent to the fluidic channel. An actuator controllably causes the deformable membrane to deflect into the fluidic channel restricting a fluidic flow in the fluidic channel. A control system is configured to tune an electrical field gradient by operating the actuator to adjust a magnitude of the deflection of the deformable membrane into the fluidic channel.
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公开(公告)号:US20190184395A1
公开(公告)日:2019-06-20
申请号:US16226165
申请日:2018-12-19
Applicant: Alexandra Ros , Daihyun Kim , Jinghui Luo
Inventor: Alexandra Ros , Daihyun Kim , Jinghui Luo
IPC: B01L3/00
CPC classification number: B01L3/502715 , B01L3/50273 , B01L3/502753 , B01L3/502761 , B01L2200/0647 , B01L2400/0406 , B01L2400/0424
Abstract: Sub-micrometer bioparticles are separated by size in a microfluidic channel utilizing a ratchet migration mechanism. A structure within the microfluidic channel includes an array of micro-posts arranged in laterally shifted rows. Reservoirs are disposed at each end of the microfluidic channel. A biased AC potential is applied across the channel via electrodes immersed into fluid in each of the reservoirs to induce a non-uniform electric field through the microfluidic channel. The applied potential comprises a first waveform with a first frequency that induces electro-kinetic flow of sub-micrometer bioparticles in the microfluidic channel, and an intermittent superimposed second waveform with a higher frequency. The second waveform selectively induces a dielectrophoretic trapping force to selectively impart ratchet migration based on particle size for separating the sub-micrometer bioparticles by size in the microfluidic channel.
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公开(公告)号:US06816817B1
公开(公告)日:2004-11-09
申请号:US09672937
申请日:2000-09-28
Applicant: Kevin Retlich , Jinghui Luo , Dave Blair
Inventor: Kevin Retlich , Jinghui Luo , Dave Blair
IPC: G06F1500
CPC classification number: H04L63/1408
Abstract: A technique for monitoring operational parameters of networked components includes storing data within each component descriptive of the component. The data is polled by a monitoring station and provides a basis for monitor views compiled in real time. The monitor views provide a view of current levels of parameters controlled or monitored by each device, such as on virtual meters. Historical levels of operational parameters may be presented in virtual strip chart output. Textual descriptions of the components are provided, along with listings of key settings. More detailed data may be accessed by links between the monitor views and other user viewable representations for the system and the specific components.
Abstract translation: 用于监视网络组件的操作参数的技术包括在描述组件的每个组件内存储数据。 数据由监控站进行轮询,并为实时编辑的监视视图提供依据。 监视器视图提供了每个设备控制或监控的参数的当前级别的视图,例如虚拟仪表。 操作参数的历史水平可以在虚拟条形图输出中呈现。 提供了组件的文字描述,以及关键设置的列表。 可以通过监视器视图和系统的其他用户可视表示之间的链接以及特定组件来访问更详细的数据。
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