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公开(公告)号:US6156338A
公开(公告)日:2000-12-05
申请号:US269515
申请日:1999-04-02
申请人: Joel Vacus , Tsiala Bouknikachvili
发明人: Joel Vacus , Tsiala Bouknikachvili
IPC分类号: C12N15/09 , A61K9/127 , A61K9/133 , A61K47/24 , A61K47/48 , A61K48/00 , C12N15/87 , C12N15/88 , C12Q1/68
CPC分类号: A61K48/00 , A61K47/488 , A61K9/1272 , C12N15/87 , C12N15/88
摘要: The invention concerns a method for preparing a composition for transferring nucleic acids consisting in contacting a nucleic acid with a cationic lipid, whereby, previous to contacting, the cationic lipid is subjected to a heating step. The invention also concerns the resulting compositions and their use.
摘要翻译: PCT No.PCT / FR97 / 01747 Sec。 一九九九年四月二日 102(e)1999年4月2日PCT PCT 1997年10月3日PCT公布。 公开号WO98 / 15639 日期1998年4月16日本发明涉及一种制备用于转移核酸的组合物的方法,所述核酸在核酸与阳离子脂质接触中接触,由此,在接触之前,对阳离子脂质进行加热步骤。 本发明还涉及所得组合物及其用途。
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2.
公开(公告)号:US6146663A
公开(公告)日:2000-11-14
申请号:US929226
申请日:1997-09-09
CPC分类号: A61K9/5153 , A61K9/5192 , Y10S977/773 , Y10S977/788 , Y10S977/795 , Y10S977/906
摘要: This invention relates to stabilized nanoparticles which may be filtered under sterile conditions, comprising at least one hydrophobic, water-insoluble and non-water-dispersible polymer or copolymer (and optionally an active principle) which is emulsified in an aqueous solution or suspension comprising a phospholipid and a bile salt.
摘要翻译: 本发明涉及可在无菌条件下过滤的稳定的纳米颗粒,其包含至少一种疏水性,水不溶性和非水分散性聚合物或共聚物(和任选的活性成分),其在水溶液或悬浮液中乳化,包括 磷脂和胆汁盐。
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