公开(公告)号：US20130153474A1

公开(公告)日：2013-06-20

申请号：US13702846

申请日：2011-06-10

申请人： Aleksandr Frorip ,  Christoph Nacke ,  Stefan Moll ,  Alex Castellarnau ,  Joern Meibaum

发明人： Aleksandr Frorip ,  Christoph Nacke ,  Stefan Moll ,  Alex Castellarnau ,  Joern Meibaum

IPC分类号： A61M1/16

CPC分类号： A61M1/1692 ,  A61M1/16 ,  A61M1/1609 ,  A61M2205/3306 ,  A61M2205/50

摘要： The invention relates to an apparatus for extracorporeal blood treatment having a dialyzer which is divided into a first and a second chamber 29, 30 by means of a semipermeable membrane wherein the first chamber 29 is arranged in a dialysate path and the second chamber 30 can be connected to a patient's blood circulation by means of a blood supply line 32 and a blood discharge line 31, an inlet 20 for fresh dialysate, an outlet 36 for spent dialysate, a measuring device 37, wherein the measuring device 37 has at least one radiation source 1 for substantially monochromatic electromagnetic radiation. Thereby the measuring device 37 for determination of a luminescence of the spent dialysate flowing through the outlet 36 has at least one detector system (5) for detecting the intensity of the electromagnetic radiation generated by luminescence.

摘要翻译： 本发明涉及一种用于体外血液处理的装置，其具有透析器，其通过半透膜被分成第一和第二腔室29,30，其中第一腔室29布置在透析液路径中，第二腔室30可以是 通过血液供应管线32和血液排出管线31连接到患者的血液循环，用于新鲜透析液的入口20，用于透析液的出口36，测量装置37，其中测量装置37具有至少一个辐射 源1用于基本上单色的电磁辐射。 因此，用于确定流过出口36的用过的透析液的发光的测量装置37具有用于检测由发光产生的电磁辐射的强度的至少一个检测器系统（5）。

公开(公告)号：US09220827B2

公开(公告)日：2015-12-29

申请号：US13816968

申请日：2011-08-17

申请人： Joern Meibaum ,  Stefan Moll ,  Alex Castellarnau

发明人： Joern Meibaum ,  Stefan Moll ,  Alex Castellarnau

IPC分类号： A61M37/00 ,  A61M1/14 ,  A61M1/16 ,  G01N21/33

CPC分类号： A61M1/14 ,  A61M1/16 ,  A61M1/1609 ,  A61M1/1613 ,  A61M1/361 ,  A61M1/3612 ,  A61M2202/0498 ,  A61M2205/3306 ,  A61M2205/3313 ,  A61M2205/52 ,  G01N21/33

摘要： The invention describes an apparatus for extracorporeal blood treatment with a dialyzer which is separated by a semipermeable membrane in to a first and second chamber (29, 30), wherein the first chamber (29) is arrange in a dialysate pathway and the second chamber (30) is connectable to the blood circulation of a patient by means of a blood supply conduit (32) and a blood return conduit (31), an inlet (20) for fresh dialysate, an outlet (30) for spent dialysate, a measuring device (37) arranged in the outlet (36), wherein said measuring device (37) has at least one radiation source consisting of several light sources (1) for electromagnetic radiation. The invention is characterized in that the measuring device (37) is designed to generate substantially monochromatic electromagnetic radiation of different wavelengths, and to lead only one of these wavelength (at the same time) though the outlet (36) for spent dialysate, wherein at least one detector system (5) is provided for detection of the intensity or the absorption of the substantially monochromatic electromagnetic radiation passing through the outlet (36) for spent dialysate.

摘要翻译： 本发明描述了一种用透析器进行体外血液处理的装置，其由半透膜分隔到第一和第二腔室（29,30）中，其中第一腔室（29）布置在透析液通路中，第二腔室 30）可通过血液供应管道（32）和血液回流管道（31），用于新鲜透析液的入口（20），用于透析液的出口（30），血液透析液 设置在所述出口（36）中的装置（37），其中所述测量装置（37）具有由用于电磁辐射的多个光源（1）组成的至少一个辐射源。 本发明的特征在于，测量装置（37）被设计成产生不同波长的基本上单色的电磁辐射，并且仅通过用于废透析液的出口（36）仅引导这些波长（同时）中的一个波长（其中在 提供了至少一个检测器系统（5），用于检测通过用于透析液的出口（36）的基本上单色的电磁辐射的强度或吸收。

公开(公告)号：US09114214B2

公开(公告)日：2015-08-25

申请号：US13994379

申请日：2011-12-14

申请人： Joern Meibaum ,  Gerhard Bock

发明人： Joern Meibaum ,  Gerhard Bock

IPC分类号： A61M37/00 ,  A61M1/30

CPC分类号： A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/306

摘要： The invention relates to an extracorporeal blood treatment apparatus with a control device (50) for controlling the opening and closing of an arterial line (2) with simultaneous closing and opening of a venous line (3) in a single-lumen-arrangement (10), with which untreated blood is removed through the single-lumen-arrangement (10) and the arterial line (2), led through a blood treatment device (5) and treated blood is fed back through the venous line (3) and the single-lumen-arrangement (10), an arterial line container (20) which is arranged in the arterial line (2) in front of the blood treatment device (5), a venous line container (30) which is arranged in the venous line (3) following the blood treatment device (5), a sensor device (31) for detecting an amount of treated blood being above a limit value in the venous line container (30), a sensor device (21) for detecting an amount of untreated blood being below a limit value in the arterial line container (20), an arterial line closure device (22) for closing the arterial line (2) with simultaneous opening of the venous line (3) in response to a signal A which is transmitted by the sensor device (31) to the arterial line closure device (22), a venous line closure device (32) for closing the venous line (3) with simultaneous opening of the arterial line (2) in response to a signal B which is transmitted by the sensor device (21) to a venous line closure device (32) and at least one pump (40) and is characterized in that a control device (50) is provided, with which a phase volume Vact is adjustable automatically in dependence on the current pumping rate QBP of the at least one pump (40) during a phase to a predefined value Vnom (FIG. 1).

摘要翻译： 本发明涉及一种具有控制装置（50）的体外血液处理装置，该控制装置（50）用于控制动脉管线（2）的打开和关闭，同时以单腔排列（10）静脉打开静脉管线（3） ），通过单腔排列（10）和动脉管线（2）除去未处理的血液，通过血液处理装置（5）引导，并且处理的血液通过静脉管线（3）反馈，并且 单腔排列（10），布置在血液处理装置（5）前方的动脉管线（2）中的动脉管路容器（20），静脉管容器（30） 在血液处理装置（5）之后的管线（3），用于检测处于静脉管路容器（30）中的限制值以上的处理血液量的传感器装置（31） 未经处理的血液低于动脉管路容器（20）中的极限值，动脉线cl 用于响应于由传感器装置（31）传送到动脉线路闭合装置（22）的信号A同时打开静脉线（3）而关闭动脉管线（2）的开口装置（22）， 用于响应于由传感器装置（21）传送到静脉闭路装置（32）的信号B同时打开动脉线（2）而关闭静脉线（3）的静脉线闭合装置（32） 和至少一个泵（40），其特征在于提供一个控制装置（50），根据所述控制装置（50），相位体积Vact根据所述至少一个泵（40）的当前泵送速率QBP自动调节 阶段到预定义值Vnom（图1）。 1）。

公开(公告)号：US20130331758A1

公开(公告)日：2013-12-12

申请号：US13994379

申请日：2011-12-14

申请人： Joern Meibaum ,  Gerhard Bock

发明人： Joern Meibaum ,  Gerhard Bock

IPC分类号： A61M1/30

CPC分类号： A61M1/30 ,  A61M1/302 ,  A61M1/303 ,  A61M1/306

摘要： The invention relates to an extracorporeal blood treatment apparatus with a control device (50) for controlling the opening and closing of an arterial line (2) with simultaneous closing and opening of a venous line (3) in a single-lumen-arrangement (10), with which untreated blood is removed through the single-lumen-arrangement (10) and the arterial line (2), led through a blood treatment device (5) and treated blood is fed back through the venous line (3) and the single-lumen-arrangement (10), an arterial line container (20) which is arranged in the arterial line (2) in front of the blood treatment device (5), a venous line container (30) which is arranged in the venous line (3) following the blood treatment device (5), a sensor device (31) for detecting an amount of treated blood being above a limit value in the venous line container (30), a sensor device (21) for detecting an amount of untreated blood being below a limit value in the arterial line container (20), an arterial line closure device (22) for closing the arterial line (2) with simultaneous opening of the venous line (3) in response to a signal A which is transmitted by the sensor device (31) to the arterial line closure device (22), a venous line closure device (32) for closing the venous line (3) with simultaneous opening of the arterial line (2) in response to a signal B which is transmitted by the sensor device (21) to a venous line closure device (32) and at least one pump (40) and is characterized in that a control device (50) is provided, with which a phase volume Vact is adjustable automatically in dependence on the current pumping rate QBP of the at least one pump (40) during a phase to a predefined value Vnom (FIG. 1).

摘要翻译： 本发明涉及一种具有控制装置（50）的体外血液处理装置，该控制装置（50）用于控制动脉管线（2）的打开和关闭，同时以单腔排列（10）静脉打开静脉管线（3） ），通过单腔排列（10）和动脉管线（2）除去未处理的血液，通过血液处理装置（5）引导，并且处理的血液通过静脉管线（3）反馈，并且 单腔排列（10），布置在血液处理装置（5）前方的动脉管线（2）中的动脉管路容器（20），静脉管容器（30） 在血液处理装置（5）之后的管线（3），用于检测处于静脉管路容器（30）中的限制值以上的处理血液量的传感器装置（31） 未经处理的血液低于动脉管路容器（20）中的极限值，动脉线cl 用于响应于由传感器装置（31）传送到动脉线路闭合装置（22）的信号A同时打开静脉线（3）而关闭动脉管线（2）的开口装置（22）， 用于响应于由传感器装置（21）传送到静脉闭路装置（32）的信号B同时打开动脉线（2）而关闭静脉线（3）的静脉线闭合装置（32） 和至少一个泵（40），其特征在于提供一个控制装置（50），根据所述控制装置（50），相位体积Vact根据所述至少一个泵（40）的当前泵送速率QBP自动调节 阶段到预定义值Vnom（图1）。 1）。

公开(公告)号：US20130237896A1

公开(公告)日：2013-09-12

申请号：US13816968

申请日：2011-08-17

申请人： Joern Meibaum ,  Stefan Moll ,  Alex Castellarnau

发明人： Joern Meibaum ,  Stefan Moll ,  Alex Castellarnau

IPC分类号： A61M1/14

CPC分类号： A61M1/14 ,  A61M1/16 ,  A61M1/1609 ,  A61M1/1613 ,  A61M1/361 ,  A61M1/3612 ,  A61M2202/0498 ,  A61M2205/3306 ,  A61M2205/3313 ,  A61M2205/52 ,  G01N21/33

摘要： The invention describes an apparatus for extracorporeal blood treatment with a dialyzer which is separated by a semipermeable membrane in to a first and second chamber (29, 30), wherein the first chamber (29) is arrange in a dialysate pathway and the second chamber (30) is connectable to the blood circulation of a patient by means of a blood supply conduit (32) and a blood return conduit (31), an inlet (20) for fresh dialysate, an outlet (30) for spent dialysate, a measuring device (37) arranged in the outlet (36), wherein said measuring device (37) has at least one radiation source consisting of several light sources (1) for electromagnetic radiation. The invention is characterized in that the measuring device (37) is designed to generate substantially monochromatic electromagnetic radiation of different wavelengths, and to lead only one of these wavelength (at the same time) though the outlet (36) for spent dialysate, wherein at least one detector system (5) is provided for detection of the intensity or the absorption of the substantially monochromatic electromagnetic radiation passing through the outlet (36) for spent dialysate.

摘要翻译： 本发明描述了一种用透析器进行体外血液处理的装置，其由半透膜分隔到第一和第二腔室（29,30）中，其中第一腔室（29）布置在透析液通路中，第二腔室 30）可通过血液供应管道（32）和血液回流管道（31），用于新鲜透析液的入口（20），用于透析液的出口（30），血液透析液 设置在所述出口（36）中的装置（37），其中所述测量装置（37）具有由用于电磁辐射的多个光源（1）组成的至少一个辐射源。 本发明的特征在于，测量装置（37）被设计成产生不同波长的基本上单色的电磁辐射，并且仅通过用于废透析液的出口（36）仅引导这些波长（同时）中的一个波长（其中在 提供了至少一个检测器系统（5），用于检测通过用于透析液的出口（36）的基本上单色的电磁辐射的强度或吸收。