公开(公告)号：US20130153474A1

公开(公告)日：2013-06-20

申请号：US13702846

申请日：2011-06-10

申请人： Aleksandr Frorip ,  Christoph Nacke ,  Stefan Moll ,  Alex Castellarnau ,  Joern Meibaum

发明人： Aleksandr Frorip ,  Christoph Nacke ,  Stefan Moll ,  Alex Castellarnau ,  Joern Meibaum

IPC分类号： A61M1/16

CPC分类号： A61M1/1692 ,  A61M1/16 ,  A61M1/1609 ,  A61M2205/3306 ,  A61M2205/50

摘要： The invention relates to an apparatus for extracorporeal blood treatment having a dialyzer which is divided into a first and a second chamber 29, 30 by means of a semipermeable membrane wherein the first chamber 29 is arranged in a dialysate path and the second chamber 30 can be connected to a patient's blood circulation by means of a blood supply line 32 and a blood discharge line 31, an inlet 20 for fresh dialysate, an outlet 36 for spent dialysate, a measuring device 37, wherein the measuring device 37 has at least one radiation source 1 for substantially monochromatic electromagnetic radiation. Thereby the measuring device 37 for determination of a luminescence of the spent dialysate flowing through the outlet 36 has at least one detector system (5) for detecting the intensity of the electromagnetic radiation generated by luminescence.

摘要翻译： 本发明涉及一种用于体外血液处理的装置，其具有透析器，其通过半透膜被分成第一和第二腔室29,30，其中第一腔室29布置在透析液路径中，第二腔室30可以是 通过血液供应管线32和血液排出管线31连接到患者的血液循环，用于新鲜透析液的入口20，用于透析液的出口36，测量装置37，其中测量装置37具有至少一个辐射 源1用于基本上单色的电磁辐射。 因此，用于确定流过出口36的用过的透析液的发光的测量装置37具有用于检测由发光产生的电磁辐射的强度的至少一个检测器系统（5）。

公开(公告)号：US09220827B2

公开(公告)日：2015-12-29

申请号：US13816968

申请日：2011-08-17

申请人： Joern Meibaum ,  Stefan Moll ,  Alex Castellarnau

发明人： Joern Meibaum ,  Stefan Moll ,  Alex Castellarnau

IPC分类号： A61M37/00 ,  A61M1/14 ,  A61M1/16 ,  G01N21/33

CPC分类号： A61M1/14 ,  A61M1/16 ,  A61M1/1609 ,  A61M1/1613 ,  A61M1/361 ,  A61M1/3612 ,  A61M2202/0498 ,  A61M2205/3306 ,  A61M2205/3313 ,  A61M2205/52 ,  G01N21/33

摘要： The invention describes an apparatus for extracorporeal blood treatment with a dialyzer which is separated by a semipermeable membrane in to a first and second chamber (29, 30), wherein the first chamber (29) is arrange in a dialysate pathway and the second chamber (30) is connectable to the blood circulation of a patient by means of a blood supply conduit (32) and a blood return conduit (31), an inlet (20) for fresh dialysate, an outlet (30) for spent dialysate, a measuring device (37) arranged in the outlet (36), wherein said measuring device (37) has at least one radiation source consisting of several light sources (1) for electromagnetic radiation. The invention is characterized in that the measuring device (37) is designed to generate substantially monochromatic electromagnetic radiation of different wavelengths, and to lead only one of these wavelength (at the same time) though the outlet (36) for spent dialysate, wherein at least one detector system (5) is provided for detection of the intensity or the absorption of the substantially monochromatic electromagnetic radiation passing through the outlet (36) for spent dialysate.

摘要翻译： 本发明描述了一种用透析器进行体外血液处理的装置，其由半透膜分隔到第一和第二腔室（29,30）中，其中第一腔室（29）布置在透析液通路中，第二腔室 30）可通过血液供应管道（32）和血液回流管道（31），用于新鲜透析液的入口（20），用于透析液的出口（30），血液透析液 设置在所述出口（36）中的装置（37），其中所述测量装置（37）具有由用于电磁辐射的多个光源（1）组成的至少一个辐射源。 本发明的特征在于，测量装置（37）被设计成产生不同波长的基本上单色的电磁辐射，并且仅通过用于废透析液的出口（36）仅引导这些波长（同时）中的一个波长（其中在 提供了至少一个检测器系统（5），用于检测通过用于透析液的出口（36）的基本上单色的电磁辐射的强度或吸收。

公开(公告)号：US20130237896A1

公开(公告)日：2013-09-12

申请号：US13816968

申请日：2011-08-17

申请人： Joern Meibaum ,  Stefan Moll ,  Alex Castellarnau

发明人： Joern Meibaum ,  Stefan Moll ,  Alex Castellarnau

IPC分类号： A61M1/14

CPC分类号： A61M1/14 ,  A61M1/16 ,  A61M1/1609 ,  A61M1/1613 ,  A61M1/361 ,  A61M1/3612 ,  A61M2202/0498 ,  A61M2205/3306 ,  A61M2205/3313 ,  A61M2205/52 ,  G01N21/33

摘要： The invention describes an apparatus for extracorporeal blood treatment with a dialyzer which is separated by a semipermeable membrane in to a first and second chamber (29, 30), wherein the first chamber (29) is arrange in a dialysate pathway and the second chamber (30) is connectable to the blood circulation of a patient by means of a blood supply conduit (32) and a blood return conduit (31), an inlet (20) for fresh dialysate, an outlet (30) for spent dialysate, a measuring device (37) arranged in the outlet (36), wherein said measuring device (37) has at least one radiation source consisting of several light sources (1) for electromagnetic radiation. The invention is characterized in that the measuring device (37) is designed to generate substantially monochromatic electromagnetic radiation of different wavelengths, and to lead only one of these wavelength (at the same time) though the outlet (36) for spent dialysate, wherein at least one detector system (5) is provided for detection of the intensity or the absorption of the substantially monochromatic electromagnetic radiation passing through the outlet (36) for spent dialysate.

摘要翻译： 本发明描述了一种用透析器进行体外血液处理的装置，其由半透膜分隔到第一和第二腔室（29,30）中，其中第一腔室（29）布置在透析液通路中，第二腔室 30）可通过血液供应管道（32）和血液回流管道（31），用于新鲜透析液的入口（20），用于透析液的出口（30），血液透析液 设置在所述出口（36）中的装置（37），其中所述测量装置（37）具有由用于电磁辐射的多个光源（1）组成的至少一个辐射源。 本发明的特征在于，测量装置（37）被设计成产生不同波长的基本上单色的电磁辐射，并且仅通过用于废透析液的出口（36）仅引导这些波长（同时）中的一个波长（其中在 提供了至少一个检测器系统（5），用于检测通过用于透析液的出口（36）的基本上单色的电磁辐射的强度或吸收。

公开(公告)号：US20120217189A1

公开(公告)日：2012-08-30

申请号：US13394021

申请日：2010-09-06

申请人： Jörn Ahrens ,  Stefan Moll ,  Alex Castellarnau

发明人： Jörn Ahrens ,  Stefan Moll ,  Alex Castellarnau

IPC分类号： A61M1/16

CPC分类号： A61M1/16 ,  A61M1/1607 ,  A61M1/1609 ,  A61M2205/3313 ,  A61M2205/3334 ,  A61M2205/50 ,  A61M2205/52

摘要： The invention is related to an apparatus for extracorporeal treatment of blood with a dialyzer which is separated by a semipermeable membrane into a first and a second chamber, wherein the first chamber is disposed in a dialysis fluid pathway and the second chamber is connectable to the blood circulation of a patient by means of a blood inflow conduit and a blood outflow conduit, a feed for fresh dialysis fluid, a discharge for spent dialysis fluid, a means for estimation of a flow QBlood in the blood inflow conduit respectively the blood outflow conduit, a means for determining a flow QDialysate in the dialysis fluid pathway, and a measuring device disposed in the discharge for estimation of the absorption ADialysate of the spent dialysis fluid flowing through the discharge, wherein the measuring device has at least one radiation source and a detector system for detection of the intensity of the electromagnetic radiation. Therein provided are a memory, wherein a formula A Blood = ( A Dialysate · Q Dialysate Q Blood ) is stored for the absorption ABlood, and an arithmetic unit for estimation of the absorption ABlood in the blood inflow conduit respectively the blood outflow conduit using the absorption ADialysate, the flow QDialysate, and the flow QBlood.

摘要翻译： 本发明涉及一种用透析器体外处理血液的装置，该透析器由半透膜分隔成第一和第二腔室，其中第一腔室设置在透析液通路中，第二腔室可连接血液 通过血液流入管道和血液流出管道，新鲜透析液体的进料，废透析液的排出物，用于分别估计血液流出管道中的血流QBlood的装置， 用于确定透析流体通路中的流动QDialysate的装置，以及设置在所述放电中用于估计流过所述放电的废透析液的吸收剂量的测量装置，其中所述测量装置具有至少一个辐射源和检测器 用于检测电磁辐射强度的系统。 其中提供了一种存储器，其中存储用于吸收ABlood的公式A Blood =（A透析液·Q透析液Q血液）和用于估计血液流入导管中的吸收ABlood的运算单元， 吸收ADDIysate，流量QDialysate和流量QBlood。

公开(公告)号：US20120228226A1

公开(公告)日：2012-09-13

申请号：US13394024

申请日：2010-09-06

申请人： Alex Castellarnau ,  Jörn Ahrens ,  Stefan Moll

发明人： Alex Castellarnau ,  Jörn Ahrens ,  Stefan Moll

IPC分类号： A61M1/16 ,  B01D61/34

CPC分类号： A61M1/16 ,  A61M1/1605 ,  A61M1/3406 ,  A61M2202/0498 ,  A61M2205/15 ,  A61M2205/3313 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2230/65

摘要： The invention relates to a method for normalizing, storing and/or displaying curves describing the adequacy of a kidney substitution treatment wherein the treatment is provided by a machine which has an extracorporeal blood system (31, 32) pumping the patient's blood at a preset flow rate through the blood chamber (30) of a dialyzer which is divided by a semi-permeable membrane into the blood chamber (30) and a dialyzing fluid chamber (29), and wherein the dialyzing fluid flows at a preset flow rate through the dialyzing fluid system (20, 36) of the machine and collects the waste products from the patient, and wherein a device (37) capable of continuously measuring any treatment related waste product is provided to deliver together with the data provided by the treatment machine an adequacy parameter, wherein curves describing the adequacy of the treatment are normalized to make them comparable, and/or stored in an adequate media and/or displayed on the user interface of the machine and wherein means are available to calculate parameters quantifying the adequacy differences between treatments.

摘要翻译： 本发明涉及一种用于归一化，存储和/或显示描述肾脏替代治疗的适当性的曲线的方法，其中所述治疗由具有体外血液系统（31,32）的机器提供，所述体外泵送患者的血液以预设的流量 通过透析器的血液室（30）通过半透膜分成血液室（30）和透析液室（29），并且其中透析液以预设的流速通过透析 流体系统（20,36），并且收集来自患者的废物，并且其中可以连续测量任何处理相关的废物的装置（37）与处理机提供的数据一起提供足够的 参数，其中描述治疗的适当性的曲线被归一化以使其相当，和/或存储在适当的介质中和/或显示在机器的用户界面上 d其中手段可用于计算量化治疗之间充分性差异的参数。

公开(公告)号：US20130303961A1

公开(公告)日：2013-11-14

申请号：US13885603

申请日：2011-11-15

申请人： Henrik Wolff ,  Stefan Moll

发明人： Henrik Wolff ,  Stefan Moll

IPC分类号： A61M1/14

CPC分类号： A61M1/14 ,  A61M1/16 ,  A61M1/1617 ,  A61M1/3403 ,  A61M1/342 ,  A61M1/3441 ,  A61M1/3609 ,  A61M2205/3331 ,  A61M2205/52 ,  A61M2230/207

摘要： The present invention relates to a method as well as a blood treatment unit for the implementation of this method for the best possible attainment of a predetermined substitution target during the ultrafiltration of blood. According to the invention, a method and a blood treatment unit for the implementation of the method is provided, wherein it is determined by detection of pressure measurement values in the blood treatment unit whether the calculated substitution target is achieved at the end of the dialysis session or not and in case of the result that the calculated substitution target cannot be achieved with the current dialysis parameters, an adjustment of the flow rate of blood, dialysate and/or substituate is performed in order to achieve the substitution target for a given treatment time in an optimal way or modify the treatment time for the given substitution target as little as possible.

摘要翻译： 本发明涉及一种方法以及用于实施该方法的血液处理单元，用于在超滤血液期间最佳地达到预定的替代目标。 根据本发明，提供了一种用于实施该方法的方法和血液处理单元，其中通过检测血液处理单元中的压力测量值来确定在透析会话结束时是否实现计算的替代目标 或者不是，并且在使用当前透析参数不能实现计算的替代目标的情况下，执行血液，透析液和/或取代物的流量的调整，以便在给定的治疗时间内实现替代靶标 以最佳方式或尽可能少地修改给定替代目标的治疗时间。

公开(公告)号：US07801746B2

公开(公告)日：2010-09-21

申请号：US10797354

申请日：2004-03-10

申请人： Stefan Moll ,  Gerhard Bock ,  Dirk Moeller ,  Sandor Dolgos

发明人： Stefan Moll ,  Gerhard Bock ,  Dirk Moeller ,  Sandor Dolgos

IPC分类号： A61B5/00 ,  G06F19/00

CPC分类号： A61M1/16 ,  A61M2205/3561 ,  A61M2205/505 ,  A61M2205/52 ,  A61M2205/84 ,  G06F19/00 ,  G06Q40/08 ,  G06Q50/22 ,  G06Q50/24 ,  Y10S128/903 ,  Y10S128/904

摘要： A dialysis station including several patient places each of which is provided with a dialyzer and a video terminal. In an internal data network, the video terminals are interlinked with each other and with a server including a data base. At a physician place, the treatment course can be followed for each patient place. If necessary, the physician may intervene and prescribe a new or changed medication appearing on the video terminal of the patient place. After having administered the medicine, the nurse acknowledges the administration of the medicine. The dialogue taking place between physician and nurse is documented in the scope of the treatment course.

摘要翻译： 一个透析站，包括几个病人场所，每个患者设置有透析器和视频终端。 在内部数据网络中，视频终端彼此互连，并且包括数据库的服务器。 在医生的地方，每个病人都可以按照治疗方法进行治疗。 必要时，医师可以介入并开出出现在患者地点的视频终端上的新药或改变的药物。 护理人员服药后，承认该药的管理。 治疗课程的范围记录了医师和护士之间的对话。

公开(公告)号：US08529485B2

公开(公告)日：2013-09-10

申请号：US12377322

申请日：2007-07-31

申请人： Gerhard Bock ,  Stefan Moll ,  Carsten Hasberg

发明人： Gerhard Bock ,  Stefan Moll ,  Carsten Hasberg

IPC分类号： A61M37/00

CPC分类号： A61M1/3653 ,  A61M1/3656 ,  A61M1/3659

摘要： The medical apparatus has lines that are connected to the vascular system of a patient. To ensure that an accidental escape of blood is identified, a camera is provided and is directed at the extracorporeal blood circuit of the patient. The image signals from the camera are processed in the sense that the color of blood and/or its arrangement in the image area in the camera image is determined, wherein the size of the recorded image area with the color of blood is also evaluated. In this way, an extracorporeal blood loss can be detected and signaled automatically.

摘要翻译： 医疗器具具有连接到患者的血管系统的线。 为了确保识别出意外的血液逸出，提供照相机并被引导到患者的体外血液回路。 在摄像机图像中的图像区域中的血液颜色和/或其排列被确定的情况下，来自相机的图像信号被处理，其中还评估了具有血液颜色的记录图像区域的尺寸。 以此方式，可以自动检测和发出体外失血。

公开(公告)号：US07873489B2

公开(公告)日：2011-01-18

申请号：US11365538

申请日：2006-03-01

申请人： Sándor Dolgos ,  G. Róbert Schin ,  Stefan Moll

发明人： Sándor Dolgos ,  G. Róbert Schin ,  Stefan Moll

IPC分类号： G06F15/00

CPC分类号： A61M1/16

摘要： A dialysis machine that monitors an elapsed time and a number of accumulated hours during a current servicing interval is disclosed. The machine executes a machine-servicing algorithm on at least the elapsed time and the accumulated operating hours to generate a projected servicing interval duration. A servicing event indicator displays servicing event schedule information based on the projected servicing interval duration. A transfusion pump, similarly equipped, is also provided.

摘要翻译： 公开了一种监测当前维修间隔期间经过时间和累积小时数的透析机。 该机器至少在经过的时间和累积的运行时间上执行机器维护算法，以产生预计的维修间隔持续时间。 服务事件指示器根据预计的服务间隔持续时间显示服务事件进度信息。 还提供了类似装备的输液泵。

公开(公告)号：US09364597B2

公开(公告)日：2016-06-14

申请号：US13885603

申请日：2011-11-15

申请人： Henrik Wolff ,  Stefan Moll

发明人： Henrik Wolff ,  Stefan Moll

IPC分类号： A61M1/14 ,  A61M1/16 ,  A61M1/34

CPC分类号： A61M1/14 ,  A61M1/16 ,  A61M1/1617 ,  A61M1/3403 ,  A61M1/342 ,  A61M1/3441 ,  A61M1/3609 ,  A61M2205/3331 ,  A61M2205/52 ,  A61M2230/207

摘要： The present invention relates to a method as well as a blood treatment unit for the implementation of this method for the best possible attainment of a predetermined substitution target during the ultrafiltration of blood. According to the invention, a method and a blood treatment unit for the implementation of the method is provided, wherein it is determined by detection of pressure measurement values in the blood treatment unit whether the calculated substitution target is achieved at the end of the dialysis session or not and in case of the result that the calculated substitution target cannot be achieved with the current dialysis parameters, an adjustment of the flow rate of blood, dialysate and/or substituate is performed in order to achieve the substitution target for a given treatment time in an optimal way or modify the treatment time for the given substitution target as little as possible.

摘要翻译： 本发明涉及一种方法以及用于实施该方法的血液处理单元，用于在超滤血液期间最佳地达到预定的替代目标。 根据本发明，提供了一种用于实施该方法的方法和血液处理单元，其中通过检测血液处理单元中的压力测量值来确定在透析会话结束时是否实现计算的替代目标 或者不是，并且在使用当前透析参数不能实现计算的替代目标的情况下，执行血液，透析液和/或取代物的流量的调整，以便在给定的治疗时间内实现替代靶标 以最佳方式或尽可能少地修改给定替代目标的治疗时间。