公开(公告)号：US4004203A

公开(公告)日：1977-01-18

申请号：US533526

申请日：1974-12-17

申请人： Brian John Chalmers ,  John Phillip Gibson

发明人： Brian John Chalmers ,  John Phillip Gibson

IPC分类号： H02P27/06 ,  B60L11/18 ,  H02P23/06 ,  H02P5/34

CPC分类号： H02P23/06 ,  B60L11/1807 ,  Y02T10/646 ,  Y02T10/648 ,  Y02T10/7005

摘要： A drive system comprises a brushless multi-phase motor which is supplied with power by way of an inverter including thyristors which are fired by a firing network. The firing network is supplied with information relative to the position of the rotor of the motor, by means of a transducer and this information flows by way of a logic network. Also provided is a current sensing device, a signal from which is passed through a control network to the logic circuit, and the logic circuit acts to modify the signals applied to the inverter in the event that the current flowing in one of the d.c. supply lines to the inverter exceeds a predetermined value for more than a predetermined length of time.

摘要翻译： 驱动系统包括无刷多相电动机，其通过包括由点火网络点火的晶闸管的逆变器供电。 通过传感器向点火网络提供相对于电动机的转子位置的信息，并且该信息通过逻辑网络流动。 还提供了电流感测装置，信号通过控制网络传递到逻辑电路，并且逻辑电路用于修改施加到逆变器的信号，其中电流在直流电流之一中流动。 到逆变器的供电线路超过预定值超过预定时间长度。

公开(公告)号：US3932798A

公开(公告)日：1976-01-13

申请号：US529753

申请日：1974-12-05

申请人： Brian John Chalmers ,  John Philip Gibson

发明人： Brian John Chalmers ,  John Philip Gibson

IPC分类号： H02M7/515

CPC分类号： H02M7/5155

摘要： An electrical inverter comprises positive and negative supply lines, first and second thyristors the anodes of which are connected to the positive line and the cathodes of which are connected respectively to the anodes of third and fourth thyristors. An oscillatory commutating circuit including a capacitor and an inductor is provided and which is connected between the anodes of the third and fourth thyristors and also a firing circuit is provided to provide gate signals to the first, fourth, third and second thyristors in that order. In addition, means is provided to over-damp the oscillatory circuit thereby to limit the commutating voltage.

摘要翻译： 电逆变器包括正负电源线，第一和第二晶闸管，其阳极连接到正极线，其阴极分别连接到第三和第四晶闸管的阳极。 提供了包括电容器和电感器的振荡换向电路，其连接在第三和第四晶闸管的阳极之间，并且还提供了一个触发电路，以按顺序向第一，第四，第三和第二晶闸管提供栅极信号。 此外，提供了用于过度阻尼振荡电路的装置，从而限制整流电压。

公开(公告)号：US2483260A

公开(公告)日：1949-09-27

申请号：US55523944

申请日：1944-09-22

申请人： JOHN CHALMERS

发明人： JOHN CHALMERS

IPC分类号： C14B1/56

CPC分类号： C14B1/56 ,  C14B2700/18

公开(公告)号：US3999700A

公开(公告)日：1976-12-28

申请号：US586503

申请日：1975-06-12

申请人： Hugh John Chalmers

发明人： Hugh John Chalmers

IPC分类号： B65D27/02 ,  B65D27/04

CPC分类号： B65D27/02 ,  B65D27/04

摘要： Multiple embodiments of a credit card mailer or mailing assembly including an envelope, a carrying member having an adhesive area thereupon for releasably engaging one or more credit cards in order to effectively immobilize the credit cards within the envelope and a wrapping member for enclosing the carrying member and masking the presence of the credit cards within the envelope.

摘要翻译： 包括信封的信用卡邮寄组件或邮寄组件的多个实施例，其中具有粘合剂区域的承载构件用于可释放地接合一个或多个信用卡，以有效地将信用卡固定在信封内，以及用于封闭承载构件的包裹构件 并屏蔽信封内信用卡的存在。

公开(公告)号：US20140023635A1

公开(公告)日：2014-01-23

申请号：US13995976

申请日：2011-12-21

申请人： Pavel Hamet ,  Johanne Tremblay ,  Ondrej Seda ,  Stephen Macmahon ,  John Chalmers

发明人： Pavel Hamet ,  Johanne Tremblay ,  Ondrej Seda ,  Stephen Macmahon ,  John Chalmers

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6883 ,  A61K31/00 ,  C12Q2600/156

摘要： The invention provides with means to predict, in subjects affected by type-2-diabetes (T2D), the probability of developing complications related to the disease. The invention involves (1) identification of genetic features such as single nucleotide polymorphisms (SNPs) for the establishment of a patient profile that can be used for prediction of complications associated with T2D. Signature profiles comprising a combination of SNPs which have greater predictive value for prognosticating particular types of complications, such as, stroke, myocardial infarction and kidney complications associated with T2D are further described. Compositions and kits that can be used with a set of complementary phenotypic markers to evaluate the risk for an individual affected by T2D to develop complications related to the disease and to evaluate the likelihood that an individual affected by type 2 diabetes type will benefit from treatments that collectively aim to reduce the risk of developing such complications.

摘要翻译： 本发明提供了在受2型糖尿病（T2D）影响的受试者中预测发生与该疾病相关的并发症的可能性的手段。 本发明涉及（1）鉴定用于建立可用于预测与T2D相关并发症的患者概况的单核苷酸多态性（SNP）等遗传特征。 进一步描述包括具有预测特定类型并发症（例如中风，心肌梗死和与T2D相关的肾并发症）的更大预测价值的SNP的组合的签名曲线。 可用于一组互补表型标志物的组合物和试剂盒，以评估受T2D影响的个体发生与该疾病相关的并发症的风险，并评估受2型糖尿病类型影响的个体可能受益于 共同旨在降低发生此类并发症的风险。

公开(公告)号：US20120134981A1

公开(公告)日：2012-05-31

申请号：US13237707

申请日：2011-09-20

申请人： Pavel HAMET ,  Johanne Tremblay ,  Ondrej Seda ,  Stephen MaCmahon ,  John Chalmers

发明人： Pavel HAMET ,  Johanne Tremblay ,  Ondrej Seda ,  Stephen MaCmahon ,  John Chalmers

IPC分类号： A61K39/395 ,  A61P9/12 ,  A61K31/713 ,  A61P9/10 ,  C40B20/00 ,  A61K31/7088

CPC分类号： C12Q1/6883 ,  C12Q2600/118 ,  C12Q2600/156 ,  C12Q2600/172

摘要： The invention provides means and methods to predict, in subjects affected by type II diabetes (T2D), the probability of developing complications which include, but are not limited to, micro/macrovascular disorder, hypertension, neuropathy, atrial fibrillation, nephropathy and other major adverse cardiovascular events (MACE) that are associated with the disease, by detecting one or more genetic features. The genetic features that are useful in prediction include, but are not limited to, genes, single nucleotide polymorphisms (SNPs) and other genomic markers. The invention further involves characterizing individuals based on the probability of developing complications related to T2D, such as, micro/macrovascular disorder, hypertension, neuropathy, atrial fibrillation, nephropathy or MACE, based on the identification of one or more aforementioned genetic features. Also described are combinations and kits for carrying out the above-described methods.

摘要翻译： 本发明提供了在受II型糖尿病（T2D）影响的受试者中预测发生并发症的可能性的手段和方法，其包括但不限于微/大血管病，高血压，神经病，心房颤动，肾病等主要 通过检测一种或多种遗传特征与疾病相关的不良心血管事件（MACE）。 在预测中有用的遗传特征包括但不限于基因，单核苷酸多态性（SNP）和其他基因组标记。 本发明还涉及基于识别一个或多个上述遗传特征，基于与T2D相关的并发症的发生概率，例如微/大血管障碍，高血压，神经病变，心房颤动，肾病或MACE，来表征个体。 还描述了用于实施上述方法的组合和试剂盒。

公开(公告)号：US20110158979A1

公开(公告)日：2011-06-30

申请号：US12997621

申请日：2009-06-15

申请人： Pavel Hamet ,  Johanne Tremblay ,  Ondrej Seda ,  Stephen Macmahon ,  John Chalmers

发明人： Pavel Hamet ,  Johanne Tremblay ,  Ondrej Seda ,  Stephen Macmahon ,  John Chalmers

IPC分类号： A61K39/395 ,  C12Q1/68 ,  C40B30/00 ,  C40B40/06 ,  A61K31/7105 ,  A61P3/10

CPC分类号： C12Q1/6883 ,  C12Q2600/106 ,  C12Q2600/156 ,  C12Q2600/172

摘要： The invention provides with means to predict, in subjects affected by type 2 diabetes (T2D), the probability of developing complications related to the disease. The invention involves 1) use of genetic features (SNPs, STRs, or other genomic markers) together with other chromosomal features and phenotypic information to establish a patient profile specifically developed for prediction of complications of T2D 2) use of a set of SNPs allowing to discriminate between individuals according to their descent. The invention also provides with methods for characterizing and selecting, within a population of subjects with type-2 diabetes, subjects that are suited for clinical trials based on the identification of one or more genetic features. Also described are combinations and kits for carrying out the above-described methods.

摘要翻译： 本发明提供了在受2型糖尿病（T2D）影响的受试者中预测发生与该疾病相关的并发症的可能性的手段。 本发明涉及1）使用遗传特征（SNP，STR或其他基因组标记）以及其他染色体特征和表型信息来建立专门为预测T2D并发症而开发的患者概况2）使用一组允许 根据他们的血统区分个人。 本发明还提供了在基于识别一种或多种遗传特征的情况下，在具有2型糖尿病的受试者群体中表征和选择适合于临床试验的受试者的方法。 还描述了用于实施上述方法的组合和试剂盒。

公开(公告)号：US20100099091A1

公开(公告)日：2010-04-22

申请号：US12457555

申请日：2009-06-15

申请人： Pavel Hamet ,  Johanne Tremblay ,  Ondrej Seda ,  Stephen Macmahon ,  John Chalmers

发明人： Pavel Hamet ,  Johanne Tremblay ,  Ondrej Seda ,  Stephen Macmahon ,  John Chalmers

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6883 ,  C12Q2600/106 ,  C12Q2600/156 ,  C12Q2600/172

摘要： The invention provides with means to predict, in subjects affected by type 2 diabetes (T2D), the probability of developing complications related to the disease. The invention involves 1) use of genetic features (SNPs, STRs, or other genomic markers) together with other chromosomal features and phenotypic information to establish a patient profile specifically developed for prediction of complications of T2D 2) use of a set of SNPs allowing to discriminate between individuals according to their descent. A preferred set of genomic markers selected for their association with complications of T2D is provided that can be used with a set of complementary phenotypic markers to evaluate the risk for an individual affected by T2D to develop complications related to the disease and to evaluate the likelihood that an individual affected by T2D type will benefit from treatments reducing the risk of developing such complications.

摘要翻译： 本发明提供了在受2型糖尿病（T2D）影响的受试者中预测发生与该疾病相关的并发症的可能性的手段。 本发明涉及1）使用遗传特征（SNP，STR或其他基因组标记）以及其他染色体特征和表型信息来建立专门为预测T2D并发症而开发的患者概况2）使用一组允许 根据他们的血统区分个人。 提供了选择与T2D并发症相关联的一组优选的基因组标记，其可与一组互补表型标志物一起使用，以评估受T2D影响的个体的风险，以发展与该疾病相关的并发症，并评估其可能性 受T2D型影响的个体将受益于减少发生此类并发症风险的治疗。

公开(公告)号：US20070268826A1

公开(公告)日：2007-11-22

申请号：US11766190

申请日：2007-06-21

申请人： Garesh Balakrishnan ,  John Chalmers ,  Clark Jeffries ,  Jitesh Nair ,  Larry Nicholson ,  Ravinder Sabhikhi ,  Raj Singh

发明人： Garesh Balakrishnan ,  John Chalmers ,  Clark Jeffries ,  Jitesh Nair ,  Larry Nicholson ,  Ravinder Sabhikhi ,  Raj Singh

IPC分类号： H04L12/56

CPC分类号： H04L47/32 ,  H04L47/10 ,  H04L47/29 ,  H04L47/30 ,  H04L49/90

摘要： A flow control method and system including an algorithm for deciding to transmit an arriving packet into a processing queue or to discard it, or, in the case of instructions or packets that must not be discarded, a similar method and system for deciding at a service event to transmit an instruction or packet into a processing queue or to skip the service event. The transmit probability is increased or decreased in consideration of minimum and maximum limits for each flow, aggregate limits for sets of flows, relative priority among flows, queue occupancy, and rate of change of queue occupancy. The effects include protection of flows below their minimum rates, correction of flows above their maximum rates, and, for flows between minimum and maximum rates, reduction of constituent flows of an aggregate that is above its aggregate maximum. Practice of the invention results in low queue occupancy during steady congestion.

摘要翻译： 一种流量控制方法和系统，包括用于决定将到达的分组发送到处理队列或丢弃它的算法，或者在不能被丢弃的指令或分组的情况下，用于在服务中决定的类似方法和系统 将指令或分组发送到处理队列或跳过服务事件的事件。 考虑到每个流量的最小和最大限制，流量集合的限制，流量之间的相对优先级，队列占用率和队列占用率的变化率，发送概率增加或减少。 这些影响包括保护流量低于其最低利率，纠正高于其最大利率的流量，以及最小和最大利率之间的流量减少总量超过其总最大值的组成流量。 本发明的实践导致在稳定拥塞期间的低队列占用。

公开(公告)号：US06393341B1

公开(公告)日：2002-05-21

申请号：US09455859

申请日：1999-12-07

申请人： David Crawford Lawrence ,  Sergei Udin ,  Eugene Wilson Hodges, IV ,  John Chalmers Sutton, III ,  Edward John Beroset ,  Sean Michael Scoggins

发明人： David Crawford Lawrence ,  Sergei Udin ,  Eugene Wilson Hodges, IV ,  John Chalmers Sutton, III ,  Edward John Beroset ,  Sean Michael Scoggins

IPC分类号： G06F1900

CPC分类号： G06F9/54 ,  G06Q30/04 ,  G06Q50/06 ,  G07F15/00

摘要： An interface layer and method is provided that permits applications, without modification, to operate with any type of meter. The interface comprises an abstraction layer and library or repository of descriptions specific to each meter type. The abstraction layer provides the capability to communicate with any meter through a variety of applications. Upon receiving an application request, the abstraction layer retrieves the description for the particular meter type from the repository and processes the request. In this manner, only one data representation is needed for applications to communicate with a wide variety of meters.

摘要翻译： 提供了一种界面层和方法，允许无需修改的应用程序就可以使用任何类型的仪表进行操作。 接口包括一个抽象层和每个仪表类型特有的描述的库或存储库。 抽象层提供通过各种应用与任何仪表通信的能力。 在接收到应用程序请求时，抽象层从存储库检索特定仪表类型的描述，并处理该请求。 以这种方式，应用程序只需要一个数据表示来与各种仪表进行通信。