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1.发明授权1,4-disubstituted pyridazine analogs there of and methods for treating SMN-deficiency-related conditions 有权其中的1,4-二取代哒嗪类似物和用于治疗SMN缺陷相关病症的方法公开(公告)号：US08729263B2
公开(公告)日：2014-05-20
申请号：US13960917
申请日：2013-08-07
申请人： Atwood Kim Cheung , Donovan Noel Chin , Natalie Dales , Aleem Fazal , Timothy Brian Hurley , John Kerrigan , Gary O'Brien , Lei Shu , Robert Sun , Moo Je Sung
发明人： Atwood Kim Cheung , Donovan Noel Chin , Natalie Dales , Aleem Fazal , Timothy Brian Hurley , John Kerrigan , Gary O'Brien , Lei Shu , Robert Sun , Moo Je Sung
IPC分类号： C07D401/00 , C07D237/30 , A01K31/00 , C07D243/08
CPC分类号： A61K31/501 , A61K31/41 , A61K31/427 , A61K31/502 , A61K31/506 , A61K31/5377 , A61K31/551 , A61K45/06 , C07D237/06 , C07D237/20 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D471/08 , C07D471/10 , C07D487/04 , C07D487/10
摘要： The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
摘要翻译： 本发明提供式I化合物或其药学上可接受的盐; 制备本发明化合物的方法及其治疗用途。 本发明还提供药理活性剂和药物组合物的组合。
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2.发明申请1,4-DISUBSTITUTED PYRIDAZINE ANALOGS THERE OF AND METHODS FOR TREATING SMN-DEFICIENCY-RELATED CONDITIONS 有权用于治疗SMN缺陷相关病症的1,4-取代吡嗪类化合物及其方法公开(公告)号：US20140051672A1
公开(公告)日：2014-02-20
申请号：US13960917
申请日：2013-08-07
申请人： Atwood Kim CHEUNG , Donovan Noel CHIN , Natalie DALES , Aleem FAZAL , Timothy Brian HURLEY , John KERRIGAN , Gary O'BRIEN , Lei SHU , Robert SUN , Moo Je SUNG
发明人： Atwood Kim CHEUNG , Donovan Noel CHIN , Natalie DALES , Aleem FAZAL , Timothy Brian HURLEY , John KERRIGAN , Gary O'BRIEN , Lei SHU , Robert SUN , Moo Je SUNG
IPC分类号： C07D401/12 , A61K45/06 , C07D409/14 , C07D401/14 , A61K31/502 , C07D413/14 , C07D417/14 , A61K31/5377 , C07D403/12 , A61K31/551 , C07D471/08 , C07D471/10 , C07D471/04 , C07D403/14 , C07D403/10 , C07D487/10 , C07D487/04 , C07D237/20 , C07D401/04 , C07D405/14 , A61K31/506 , A61K31/501
CPC分类号： A61K31/501 , A61K31/41 , A61K31/427 , A61K31/502 , A61K31/506 , A61K31/5377 , A61K31/551 , A61K45/06 , C07D237/06 , C07D237/20 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D471/08 , C07D471/10 , C07D487/04 , C07D487/10
摘要： The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
摘要翻译： 本发明提供式I化合物或其药学上可接受的盐; 制备本发明化合物的方法及其治疗用途。 本发明还提供药理活性剂和药物组合物的组合。
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3.发明申请公开(公告)号：US20140213570A1
公开(公告)日：2014-07-31
申请号：US14242282
申请日：2014-04-01
申请人： Atwood Kim CHEUNG , Donovan Noel CHIN , Natalie DALES , Aleem FAZAL , Timothy HURLEY , John KERRIGAN , Gary O'BRIEN , Lei SHU , Robert SUN , Moo Je SUNG
发明人： Atwood Kim CHEUNG , Donovan Noel CHIN , Natalie DALES , Aleem FAZAL , Timothy HURLEY , John KERRIGAN , Gary O'BRIEN , Lei SHU , Robert SUN , Moo Je SUNG
IPC分类号： C07D401/14 , A61K31/5377 , C07D487/04 , A61K31/501 , C07D401/12 , C07D471/10 , C07D471/04 , C07D413/14 , C07D417/14 , C07D403/12 , C07D403/14 , C07D487/10 , A61K31/551 , C07D409/14
CPC分类号： A61K31/501 , A61K31/41 , A61K31/427 , A61K31/502 , A61K31/506 , A61K31/5377 , A61K31/551 , A61K45/06 , C07D237/06 , C07D237/20 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/10 , C07D403/12 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D471/08 , C07D471/10 , C07D487/04 , C07D487/10
摘要： The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
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