-
公开(公告)号：US20100279337A1
公开(公告)日：2010-11-04
申请号：US12835307
申请日：2010-07-13
申请人： John Ryals , Mike Milburn , Matthew W. Mitchell , Kay A. Lawton
发明人： John Ryals , Mike Milburn , Matthew W. Mitchell , Kay A. Lawton
CPC分类号： G01N33/5091 , C12Q1/6876 , C12Q1/6883 , G01N30/7233 , G01N33/5023 , G01N2800/7042
摘要： Biomarkers relating to metabolic age are provided, as well as methods for using such biomarkers as biomarkers for determining metabolic age. In addition, methods for modulating the metabolic age of a subject are also provided. Also provided are suites of small molecule entities as biomarkers for metabolic age.
摘要翻译： 提供与代谢年龄相关的生物标志物，以及使用这些生物标志物作为生物标志物来确定代谢年龄的方法。 此外，还提供了调节受试者的代谢年龄的方法。 还提供了小分子实体的套件作为代谢年龄的生物标志物。
-
公开(公告)号：US07781160B2
公开(公告)日：2010-08-24
申请号：US11871752
申请日：2007-10-12
申请人： John Ryals , Mike Milburn , Matthew W. Mitchell , Kay A. Lawton
发明人： John Ryals , Mike Milburn , Matthew W. Mitchell , Kay A. Lawton
IPC分类号： C12Q1/00
CPC分类号： G01N33/5091 , C12Q1/6876 , C12Q1/6883 , G01N30/7233 , G01N33/5023 , G01N2800/7042
摘要： Biomarkers relating to metabolic age are provided, as well as methods for using such biomarkers as biomarkers for determining metabolic age. In addition, methods for modulating the metabolic age of a subject are also provided. Also provided are suites of small molecule entities as biomarkers for metabolic age.
摘要翻译： 提供与代谢年龄相关的生物标志物，以及使用这些生物标志物作为生物标志物来确定代谢年龄的方法。 此外，还提供了调节受试者的代谢年龄的方法。 还提供了小分子实体的套件作为代谢年龄的生物标志物。
-
公开(公告)号：US6054637A
公开(公告)日：2000-04-25
申请号：US329799
申请日：1994-10-26
申请人： Thomas Boller , Jean-Marc Neuhaus , John Ryals
发明人： Thomas Boller , Jean-Marc Neuhaus , John Ryals
IPC分类号： A01H1/00 , A01H5/00 , C07K7/06 , C07K7/08 , C07K14/00 , C07K14/415 , C12N1/21 , C12N5/10 , C12N9/24 , C12N9/42 , C12N15/09 , C12N15/29 , C12N15/56 , C12N15/62 , C12N15/82 , A01H5/10 , C12N5/14 , C12N15/52
CPC分类号： C07K7/08 , C07K14/415 , C12N15/625 , C12N15/8221 , C12N9/244 , C12N9/2442 , C12Y302/01006 , C12Y302/01008 , C12Y302/01014 , C12Y302/01039 , C12Y302/01058 , C12Y302/01073 , A01K2217/05 , C07K2319/00
摘要： The present invention relates to novel peptide fragments [targeting signal] that are obtainable from the C-terminal region [C-terminal extension] of plant vacuole proteins and that, in operable linkage with any desired protein molecule, ensure that the proteins associated with those peptide fragments are directed specifically into the plant vacuole, and to DNA molecules coding for the said peptide fragments.The present invention relates also to recombinant DNA molecules that comprise the DNA sequence according to the invention in operable linkage with an expressible DNA, and to the vectors derived therefrom. Also included are host cells and/or host organisms, including transgenic plants, that comprise the said recombinant DNA or the vectors derived therefrom. The present invention also relates to recombinant DNA molecules and vectors derived therefrom that comprise DNA sequences naturally coding for vacuolar proteins, but which are devoid of vacuole signal sequences and targeted for extracellular secretion.
摘要翻译： 本发明涉及可从植物液泡蛋白的C-末端区域[C-末端延伸]获得的新的肽片段[靶向信号]，并且与任何所需的蛋白质分子可操作地连接，确保与这些蛋白质相关的蛋白质 肽片段特异性地引导到植物液泡中，以及编码所述肽片段的DNA分子。 本发明还涉及包含根据本发明的DNA序列与可表达的DNA可操作地连接的重组DNA分子以及由其衍生的载体。 还包括宿主细胞和/或宿主生物，包括转基因植物，其包含所述重组DNA或由其衍生的载体。 本发明还涉及重组DNA分子及其衍生的载体，其包含天然编码液泡蛋白但没有液泡信号序列并靶向细胞外分泌的DNA序列。
-
公开(公告)号：US20080124752A1
公开(公告)日：2008-05-29
申请号：US11871752
申请日：2007-10-12
申请人： John RYALS , Mike Milburn , Matthew W. Mitchell , Kay A. Lawton
发明人： John RYALS , Mike Milburn , Matthew W. Mitchell , Kay A. Lawton
CPC分类号： G01N33/5091 , C12Q1/6876 , C12Q1/6883 , G01N30/7233 , G01N33/5023 , G01N2800/7042
摘要： Biomarkers relating to metabolic age are provided, as well as methods for using such biomarkers as biomarkers for determining metabolic age. In addition, methods for modulating the metabolic age of a subject are also provided. Also provided are suites of small molecule entities as biomarkers for metabolic age.
摘要翻译： 提供与代谢年龄相关的生物标志物，以及使用这些生物标志物作为生物标志物来确定代谢年龄的方法。 此外，还提供了调节受试者的代谢年龄的方法。 还提供了小分子实体的套件作为代谢年龄的生物标志物。
-
-
-
搜索结果
4 条记录 (耗时 0.012 秒)
