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1.发明申请Nucleation of Drug Delivery Balloons to Provide Improved Crystal Size and Density 审中-公开药物递送气球的成核提供改善的晶体尺寸和密度公开(公告)号：US20110015664A1
公开(公告)日：2011-01-20
申请号：US12815138
申请日：2010-06-14
申请人： Steve Kangas , Michael Sean Owens , Jon Patterson , Dave Ekberg , Erik Haun , Eric Henderson , Aaron Foss , Yen-Lane Chen
发明人： Steve Kangas , Michael Sean Owens , Jon Patterson , Dave Ekberg , Erik Haun , Eric Henderson , Aaron Foss , Yen-Lane Chen
CPC分类号： A61L29/16 , A61L29/06 , A61L2300/416 , A61L2300/606 , A61L2300/622 , A61L2300/63 , C08L77/00
摘要： Drug delivery balloons have densely packed crystals of small particle size of the drug thereon. An amorphous drug coating is applied to a balloon surface and annealed to provide the crystals. The balloon surface is nucleated to induce formation of drug crystals in the annealing step to provide the crystals in high density with small size.
摘要翻译： 药物递送气球具有致密填充的粒子尺寸小的晶体。 将无定形药物涂层施加到球囊表面并退火以提供晶体。 在退火步骤中，气球表面成核以诱导药物晶体的形成，以便以高密度小尺寸提供晶体。
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公开(公告)号：US10080821B2
公开(公告)日：2018-09-25
申请号：US12815138
申请日：2010-06-14
申请人： Steve Kangas , Michael Sean Owens , Jon Patterson , Dave Ekberg , Erik Haun , Eric Henderson , Aaron Foss , Yen-Lane Chen
发明人： Steve Kangas , Michael Sean Owens , Jon Patterson , Dave Ekberg , Erik Haun , Eric Henderson , Aaron Foss , Yen-Lane Chen
CPC分类号： A61L29/16 , A61L29/06 , A61L2300/416 , A61L2300/606 , A61L2300/622 , A61L2300/63 , C08L77/00
摘要： Drug delivery balloons have densely packed crystals of small particle size of the drug thereon. An amorphous drug coating is applied to a balloon surface and annealed to provide the crystals. The balloon surface is nucleated to induce formation of drug crystals in the annealing step to provide the crystals in high density with small size.
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