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公开(公告)号：US20180271079A1
公开(公告)日：2018-09-27
申请号：US15918714
申请日：2018-03-12
申请人： Joseph C. Matteo
发明人： Joseph C. Matteo
IPC分类号： A01K97/12 , A01K89/033
CPC分类号： A01K97/12 , A01K89/016 , A01K89/051
摘要： A fly-fishing reel having an integrated incremental meter device along with a modular weight system for customizing the weight of the fly-fishing reel in order for an angler to use the fly-fishing reel with a variety of fly rods and still maintain a desired balance point. The modular weight system allows the balance point of the rod and fly-fishing reel to be adjusted. The incremental metering device is adapted for keeping a tally of selected data, such as, though not limited to the number of fish caught or released.
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公开(公告)号：US07718436B2
公开(公告)日：2010-05-18
申请号：US10421324
申请日：2003-04-23
IPC分类号： G01N23/00
CPC分类号： G01N35/1079 , G01N35/1002 , Y10T436/25625 , Y10T436/2575
摘要： A method of producing multiple batches of a radiopharmaceutical, such as FDG. The method includes the steps of transferring the appropriate liquids to a production apparatus, processing the liquids to produce the radiopharmaceutical, delivering the radiopharmaceutical to a container, automatically cleaning the apparatus, and repeating the previous steps, as desired. The apparatus for multi-batch production of FDG includes a reagent delivery system, a reaction vessel, a filter assembly, and a control system. The combination of these components provides a method that is capable of producing multiple batches of a radiopharmaceutical with minimal operator intervention and, consequently, minimal radiation exposure.
摘要翻译： 一种生产多批放射性药物的方法，如FDG。 该方法包括以下步骤：将适当的液体转移到生产设备，处理液体以产生放射性药物，将放射性药物输送到容器，自动清洁装置，并根据需要重复前述步骤。 用于多批次生产FDG的装置包括试剂递送系统，反应容器，过滤器组件和控制系统。 这些组分的组合提供了一种方法，其能够以最少的操作者干预和因此最小的辐射照射来生产多批放射性药物。
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3.发明授权Modular and reconfigurable multi-stage high temperature microreactor cartridge apparatus and system for using same 有权模块化和可重新配置的多级高温微反应器墨盒装置及其使用方法公开(公告)号：US07854902B2
公开(公告)日：2010-12-21
申请号：US11843458
申请日：2007-08-22
申请人： Joseph C. Matteo
发明人： Joseph C. Matteo
IPC分类号： B01J10/00
CPC分类号： B01J19/0093 , B01J2219/00783 , B01J2219/00788 , B01J2219/0081 , B01J2219/00822 , B01J2219/00824 , B01J2219/00826 , B01J2219/00831 , B01J2219/0086 , B01J2219/00871 , B01J2219/00891 , B01J2219/00909
摘要： A microfluidic reactor cartridge having glass capillary tubing wound in a coil and surrounded by a ceramic housing capable use in high temperatures and method for using same. In another embodiment, the microfluidic cartridge is a serpentine reactor cartridge with a serpentine microreactor channel formed in a ceramic housing. The serpentine reactor cartridge has an inlet tube attached to its inlet port and an outlet tube attached to its outlet port. The inlet port is a macro/micro interface and the outlet port is a micro/macro interface useful in gas phase reactions where solids must be used to produce a reactant. The method for using a microfluidic reactor cartridge includes two phases, the first phase for producing a radioactive labeled gas such as methyl iodide and the second phase is a methylation reaction.
摘要翻译： 一种微流体反应器筒，其具有缠绕在线圈中的玻璃毛细管并被能够在高温下使用的陶瓷壳体包围，并且使用该陶瓷壳体的方法。 在另一个实施方案中，微流控筒是具有形成在陶瓷壳体中的蛇形微反应器通道的蛇形反应器筒。 蛇形反应器盒具有连接到其入口的入口管和附接到其出口的出口管。 入口是宏/微接口，出口是用于气相反应的微/宏界面，其中固体必须用于产生反应物。 使用微流体反应器筒的方法包括两相，用于产生放射性标记气体如甲基碘的第一相和第二相是甲基化反应。
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4.发明授权公开(公告)号：US07790124B2
公开(公告)日：2010-09-07
申请号：US12632027
申请日：2009-12-07
申请人： Joseph C. Matteo
发明人： Joseph C. Matteo
IPC分类号： B01J14/00
CPC分类号： B01L3/502715 , B01L3/565 , B01L9/527 , B01L2200/027 , B01L2200/028 , B01L2300/0803 , B01L2300/0816 , B01L2300/0874 , B01L2300/18 , B01L2400/0406
摘要： A modular and reconfigurable multi-stage microreactor cartridge apparatus provides a manifold for removably attaching multiple microfluidic components such as microreactors. The microfluidic components are attached at microfluidic component ports having two input/output terminals, which microfluidic component ports are connected via connections internal to the manifold to other microfluidic component ports providing a microfluidic circuit. The microfluidic component may be a microfluidic circuit plug-in or a cartridge having a mounting block with two input/output terminals and a fastener aperture and fluidic tubing having a first and second transport portion and a body portion, the three portions being disposed in substantially parallel planes and the body portion being would in a coil around a spool. The coil is connected to the mounting block by either epoxy protector or L-bracket. The cartridge has a first and a second remote input/output terminal connected to the first and second transport lines respectively.
摘要翻译： 模块化和可重新配置的多级微反应器盒装置提供用于可移除地附接多个微流体部件如微反应器的歧管。 微流体组件连接在具有两个输入/输出端子的微流体组分端口处，该微流体组分端口通过歧管内部的连接连接到提供微流体电路的其它微流体组分端口。 微流体组件可以是微流体电路插件或具有带有两个输入/输出端子的安装块和具有第一和第二传送部分和主体部分的紧固件孔和流体管的微盒，所述三个部分基本上 平行的平面和主体部分将围绕线轴缠绕在线圈中。 线圈通过环氧树脂保护器或L型支架连接到安装块。 盒具有分别连接到第一和第二传输线的第一和第二远程输入/输出端子。
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5.发明授权公开(公告)号：US07641860B2
公开(公告)日：2010-01-05
申请号：US11421678
申请日：2006-06-01
申请人： Joseph C. Matteo
发明人： Joseph C. Matteo
CPC分类号： B01L3/502715 , B01L3/565 , B01L9/527 , B01L2200/027 , B01L2200/028 , B01L2300/0803 , B01L2300/0816 , B01L2300/0874 , B01L2300/18 , B01L2400/0406
摘要： A modular and reconfigurable multi-stage microreactor cartridge apparatus provides a manifold for removably attaching multiple microfluidic components such as microreactors. The microfluidic components are attached at microfluidic component ports having two input/output terminals, which microfluidic component ports are connected via connections internal to the manifold to other microfluidic component ports providing a microfluidic circuit. The microfluidic component may be a microfluidic circuit plug-in or a cartridge having a mounting block with two input/output terminals and a fastener aperture and fluidic tubing having a first and second transport portion and a body portion, the three portions being disposed in substantially parallel planes and the body portion being would in a coil around a spool. The coil is connected to the mounting block by either epoxy protector or L-bracket. The cartridge has a first and a second remote input/output terminal connected to the first and second transport lines respectively.
摘要翻译： 模块化和可重新配置的多级微反应器盒装置提供用于可移除地附接多个微流体部件如微反应器的歧管。 微流体组件连接在具有两个输入/输出端子的微流体组分端口处，该微流体组分端口通过歧管内部的连接连接到提供微流体电路的其它微流体组分端口。 微流体组件可以是微流体电路插件或具有带有两个输入/输出端子的安装块和具有第一和第二传送部分和主体部分的紧固件孔和流体管的微盒，所述三个部分基本上 平行的平面和主体部分缠绕在卷轴周围的线圈中。 线圈通过环氧树脂保护器或L型支架连接到安装块。 盒具有分别连接到第一和第二传输线的第一和第二远程输入/输出端子。
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公开(公告)号：US6122981A
公开(公告)日：2000-09-26
申请号：US169097
申请日：1998-10-09
申请人： Joseph C. Matteo
发明人： Joseph C. Matteo
CPC分类号： B25J9/102 , Y10T74/18848 , Y10T74/19074 , Y10T74/20323
摘要： A triple epicyclic differential transmission for converting three parallel inputs to three orthogonal outputs. The triple epicyclic differential transmission includes three input shaft/pinion assemblies and a ring gear assembly which includes three ring gear pairs--each pair driven by an input shaft/pinion assembly in an epicyclic manner. An outer structure assembly is rotatably mounted to the ring gear assembly and an idle pulley assembly is pivotably mounted to the outer structure assembly. An output pulley assembly is rotatably mounted to the idle pulley assembly and driven by the ring gear assembly via the idle pulley assembly.
摘要翻译： 用于将三个并行输入转换为三个正交输出的三重行星差分传输。 三重行星差速器传动装置包括三个输入轴/小齿轮组件和一个环形齿轮组件，其包括三个环形齿轮对，每对齿轮对由输入轴/小齿轮组件以行星方式驱动。 外部结构组件可旋转地安装到环形齿轮组件，并且空转滑轮组件可枢转地安装到外部结构组件。 输出滑轮组件可旋转地安装到空转滑轮组件并且经由空转滑轮组件由齿圈组件驱动。
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公开(公告)号：US07998418B1
公开(公告)日：2011-08-16
申请号：US11754623
申请日：2007-05-29
申请人： Joseph C. Matteo
发明人： Joseph C. Matteo
CPC分类号： B01J19/0093 , B01J2219/00795 , B01J2219/00822 , B01J2219/00831 , B01J2219/00833 , B01J2219/0086 , B01J2219/00867 , B01J2219/00873 , B01J2219/0088 , Y10T436/11 , Y10T436/25 , Y10T436/25375 , Y10T436/2575 , Y10T436/25875
摘要： An evaporator and concentrator in a reactor and loading system concentrates ions such as fluoride ions in some embodiments, and evaporates micro- to milliliter volumes of liquid solutions including intermediate and final product in other embodiments. It efficiently re-dissolves the evaporated solution generating a product, which is transferred to an external system as desired. The external system may be a micro-fluidic reactor system and/or loading system. The evaporator/concentrator has an input port for introducing liquids and solids. A capillary tube introduces gas, such as nitrogen gas, into a volume of solution contained within a v-vial, which produces an evaporating micro bubbler. A concentric tube, surrounding the capillary tube in some embodiments, introduces gas into the empty volume above the solution inside the v-vial, which is referred to as a vapor sweep. The vapor sweep assists in removing the evaporated solution from the v-vial through a vacuum tube.
摘要翻译： 在一些实施方案中，反应器和负载系统中的蒸发器和浓缩器集中离子如氟离子，并且在其它实施方案中蒸发微至数毫升的液体溶液，包括中间体和最终产物。 它有效地重新溶解产生产品的蒸发溶液，根据需要将其转移到外部系统。 外部系统可以是微流体反应器系统和/或加载系统。 蒸发器/浓缩器具有用于引入液体和固体的输入端口。 毛细管将诸如氮气的气体引入包含在v型小瓶内的一定体积的溶液中，其产生蒸发的微型起泡器。 在一些实施例中，围绕毛细管的同心管将气体引入V型瓶内溶液上方的空体积，这被称为蒸气扫描。 蒸汽扫描有助于通过真空管从V型瓶中除去蒸发的溶液。
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公开(公告)号：US20070280855A1
公开(公告)日：2007-12-06
申请号：US11421678
申请日：2006-06-01
申请人： Joseph C. Matteo
发明人： Joseph C. Matteo
IPC分类号： B01L3/02
CPC分类号： B01L3/502715 , B01L3/565 , B01L9/527 , B01L2200/027 , B01L2200/028 , B01L2300/0803 , B01L2300/0816 , B01L2300/0874 , B01L2300/18 , B01L2400/0406
摘要： A modular and reconfigurable multi-stage microreactor cartridge apparatus provides a manifold for removably attaching multiple microfluidic components such as microreactors. The microfluidic components are attached at microfluidic component ports having two input/output terminals, which microfluidic component ports are connected via connections internal to the manifold to other microfluidic component ports providing a microfluidic circuit. The microfluidic component may be a microfluidic circuit plug-in or a cartridge having a mounting block with two input/output terminals and a fastener aperture and fluidic tubing having a first and second transport portion and a body portion, the three portions being disposed in substantially parallel planes and the body portion being would in a coil around a spool. The coil is connected to the mounting block by either epoxy protector or L-bracket. The cartridge has a first and a second remote input/output terminal connected to the first and second transport lines respectively.
摘要翻译： 模块化和可重新配置的多级微反应器盒装置提供用于可移除地附接多个微流体部件如微反应器的歧管。 微流体组件连接在具有两个输入/输出端子的微流体组分端口处，该微流体组分端口通过歧管内部的连接连接到提供微流体电路的其它微流体组分端口。 微流体组件可以是微流体电路插件或具有带有两个输入/输出端子的安装块和具有第一和第二传送部分和主体部分的紧固件孔和流体管的微盒，所述三个部分基本上 平行的平面和主体部分缠绕在卷轴周围的线圈中。 线圈通过环氧树脂保护器或L型支架连接到安装块。 盒具有分别连接到第一和第二传输线的第一和第二远程输入/输出端子。
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公开(公告)号：US10667505B2
公开(公告)日：2020-06-02
申请号：US15918714
申请日：2018-03-12
申请人： Joseph C. Matteo
发明人： Joseph C. Matteo
IPC分类号： A01K89/01 , A01K97/12 , A01K89/033 , A01K89/016
摘要： A fly-fishing reel having an integrated incremental meter device along with a modular weight system for customizing the weight of the fly-fishing reel in order for an angler to use the fly-fishing reel with a variety of fly rods and still maintain a desired balance point. The modular weight system allows the balance point of the rod and fly-fishing reel to be adjusted. The incremental metering device is adapted for keeping a tally of selected data, such as, though not limited to the number of fish caught or released.
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10.发明申请公开(公告)号：US20100098594A1
公开(公告)日：2010-04-22
申请号：US12632027
申请日：2009-12-07
申请人： Joseph C. Matteo
发明人： Joseph C. Matteo
CPC分类号： B01L3/502715 , B01L3/565 , B01L9/527 , B01L2200/027 , B01L2200/028 , B01L2300/0803 , B01L2300/0816 , B01L2300/0874 , B01L2300/18 , B01L2400/0406
摘要： A modular and reconfigurable multi-stage microreactor cartridge apparatus provides a manifold for removably attaching multiple microfluidic components such as microreactors. The microfluidic components are attached at microfluidic component ports having two input/output terminals, which microfluidic component ports are connected via connections internal to the manifold to other microfluidic component ports providing a microfluidic circuit. The microfluidic component may be a microfluidic circuit plug-in or a cartridge having a mounting block with two input/output terminals and a fastener aperture and fluidic tubing having a first and second transport portion and a body portion, the three portions being disposed in substantially parallel planes and the body portion being would in a coil around a spool. The coil is connected to the mounting block by either epoxy protector or L-bracket. The cartridge has a first and a second remote input/output terminal connected to the first and second transport lines respectively.
摘要翻译： 模块化和可重新配置的多级微反应器盒装置提供用于可移除地附接多个微流体部件如微反应器的歧管。 微流体组件连接在具有两个输入/输出端子的微流体组分端口处，该微流体组分端口通过歧管内部的连接连接到提供微流体电路的其它微流体组分端口。 微流体组件可以是微流体电路插件或具有带有两个输入/输出端子的安装块和具有第一和第二传送部分和主体部分的紧固件孔和流体管的微盒，所述三个部分基本上 平行的平面和主体部分将围绕线轴缠绕在线圈中。 线圈通过环氧树脂保护器或L型支架连接到安装块。 盒具有分别连接到第一和第二传输线的第一和第二远程输入/输出端子。
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