公开(公告)号：US20240288463A1

公开(公告)日：2024-08-29

申请号：US18573306

申请日：2023-06-13

Applicant: SHENZHEN JINGTAI TECHNOLOGY CO., LTD.

Inventor： Jianqing LIU ,  Yang LIU ,  Jiandong GAO

IPC: G01N35/10 ,  B01L3/00 ,  G01N35/00 ,  G01N35/04

CPC classification number: G01N35/1002 ,  B01L3/565 ,  G01N35/0099 ,  G01N2035/0496 ,  G01N2035/0498

Abstract: A solvent storage device and a liquid transfer system. The solvent storage device is provided with at least one layer of a frame which has a receiving chamber with an opening. A container carrying assembly for carrying containers is arranged in, and the container carrying assembly is provided with a plurality of container placement parts. The container carrying assembly is connected to the frame through a first moving mechanism for driving the container carrying assembly to move in a straight line at the opening. Accordingly, the space occupied by a plurality of containers can be reduced and the liquid transfer operation is more convenient.

公开(公告)号：US12072343B2

公开(公告)日：2024-08-27

申请号：US17062288

申请日：2020-10-02

Applicant: Illumina, Inc.

Inventor： Johanna L. Whitacre ,  Steven S. Phelps ,  Bradley Kent Drews ,  Debra Sue Bryan, II ,  Michael A. Niziolek ,  Joshua A. Darland ,  Umberto Ulmanella ,  Michael Dai Wang ,  Michelle L. Alvarez ,  Stephen Wayne Clark

IPC: G01N35/10 ,  B01F23/40 ,  B01F23/45 ,  B01F25/10 ,  B01F25/433 ,  B01F31/65 ,  B01F33/84 ,  B01F35/53 ,  B01F35/71 ,  B01F35/75 ,  B01L3/00 ,  B01L3/02 ,  C12Q1/6874 ,  G01N35/00 ,  B01F101/23

CPC classification number: G01N35/1016 ,  B01F23/45 ,  B01F23/49 ,  B01F25/103 ,  B01F25/4331 ,  B01F31/651 ,  B01F33/84 ,  B01F35/53 ,  B01F35/7176 ,  B01F35/7544 ,  B01L3/0293 ,  B01L3/502 ,  B01L3/527 ,  C12Q1/6874 ,  G01N35/00584 ,  G01N35/1002 ,  G01N35/1097 ,  B01F2101/23 ,  B01L2200/0621 ,  B01L2200/16 ,  B01L2300/06 ,  B01L2300/0867 ,  B01L2300/0883 ,  B01L2400/0487 ,  B01L2400/0622 ,  B01L2400/0633 ,  B01L2400/086 ,  G01N2035/1058

Abstract: A method includes, under control of control circuitry implementing a mixing protocol, aspirating reagents from multiple different reagent reservoirs into a cache channel. Designated amounts of the reagents are automatically aspirated from the corresponding reagent reservoirs by corresponding sippers based on the mixing protocol implemented by the control circuitry. The method also includes discharging the reagents from the cache channel into a mixing reservoir, and mixing the reagents within the mixing reservoir to form a reagent mixture.

公开(公告)号：US12070750B2

公开(公告)日：2024-08-27

申请号：US17981035

申请日：2022-11-04

Applicant: ILLUMINA, INC.

Inventor： Paul Crivelli ,  Cyril Delattre

IPC: B01L3/00 ,  G01N35/10

CPC classification number: B01L3/502715 ,  B01L3/502707 ,  B01L3/502738 ,  G01N35/1002 ,  B01L2200/12 ,  B01L2300/044 ,  B01L2300/047 ,  B01L2300/0645 ,  B01L2300/0816 ,  B01L2300/0887 ,  B01L2300/12 ,  B01L2300/123 ,  B01L2400/06

Abstract: An apparatus includes a fluid reservoir and a laminate fluidic circuit positioned above the fluid reservoir. The laminate fluidic circuit includes two or more layers laminated together to define a substantially planar substrate and one or more channels defined within the substrate. The laminate fluidic circuit includes a flexible conduit defined by a portion of the substrate encompassing an extent of at least one of the channels that is partially separated or separable from the remainder of the substrate. The flexible conduit is deflectable with respect to the planar substrate toward the fluid reservoir such that the flexible conduit fluidly connects the at least one channel to the fluid reservoir.

公开(公告)号：US12070744B2

公开(公告)日：2024-08-27

申请号：US17526943

申请日：2021-11-15

Applicant: ILLUMINA, INC.

Inventor： Ahmadreza Rashedi ,  Gregory Holst ,  Rajagopal Panchapakesan

IPC: B01L3/00 ,  G01N35/10

CPC classification number: B01L3/502 ,  G01N35/1002 ,  G01N35/1016 ,  B01L2200/026 ,  B01L2200/143 ,  B01L2200/16 ,  B01L2300/0654 ,  B01L2300/0663 ,  B01L2300/0877 ,  B01L2400/06

Abstract: Valve assemblies and related systems are disclosed. An apparatus includes or comprises a system including or comprising an imaging system, a flow cell interface having a corresponding flow cell receptacle, a stage assembly, and a valve assembly including or comprising a valve and a valve drive assembly. The stage assembly moves the flow cell interface relative to the imaging system and the valve drive assembly is to drive the valve using shaped input signals to reduce vibration imposed on at least one of the stage assembly or another component of the apparatus based on movement of the valve.

公开(公告)号：US12061208B2

公开(公告)日：2024-08-13

申请号：US17265231

申请日：2019-06-21

Applicant: HITACHI HIGH-TECH CORPORATION

Inventor： Taichiro Yamashita ,  Takenori Okusa ,  Susumu Sakairi

IPC: B01L99/00 ,  B01L3/00 ,  G01N21/13 ,  G01N35/00 ,  G01N35/02 ,  G01N35/10 ,  G01N21/01 ,  G01N35/04

CPC classification number: G01N35/025 ,  B01L3/523 ,  G01N21/13 ,  G01N35/1002 ,  B01L2300/041 ,  G01N2021/0112 ,  G01N2021/0187 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444

Abstract: The automatic analysis device includes: a reagent tank that holds a reagent container that contains a reagent; and a lid opening/closing device including a lid opening/closing member configured to be movable in a first direction parallel to a vertical direction and a second direction perpendicular to the first direction. The lid opening/closing member has a first member for opening a lid of the reagent container and a second member for closing the lid. The lid opening/closing member is configured to be movable between a first position and a second position, the first position located above the reagent container and the second position located below the first position in the first direction such that the bottom surface of the lid opening/closing member comes into contact with the reagent container, and the lid opening/closing member is configured to be movable between the second position and a third position that is away from the second position in the second direction.

公开(公告)号：US20240264190A1

公开(公告)日：2024-08-08

申请号：US18434924

申请日：2024-02-07

Applicant: CANON MEDICAL SYSTEMS CORPORATION

Inventor： Takahiro SEMACHI ,  Isamu MATSUDA ,  Makoto OGASAWARA ,  Kiwamu KODAMA ,  Yuki SHIMODAIRA ,  Yuya KOMORI

IPC: G01N35/10 ,  G01N35/02

CPC classification number: G01N35/1004 ,  G01N35/025 ,  G01N35/1002

Abstract: An automatic analyzer includes a probe, a detector, and a controller. The probe sucks and discharges a sample and/or a reagent. The detector detects that the probe is in contact with a liquid. The controller detects that a liquid droplet adheres to the probe based on a detection result of the detector.

公开(公告)号：US20240240171A1

公开(公告)日：2024-07-18

申请号：US18560380

申请日：2021-12-24

Applicant: AUTOBIO LABTEC INSTRUMENTS CO., LTD.

Inventor： Chao WANG ,  Zhenkun LI ,  Long SUN ,  Peng ZHAO ,  Yaoji LIU ,  Haoran WEN ,  Weiye GAO ,  Chaohui ZHANG ,  Cong LIU

IPC: C12N15/10 ,  B01L7/00 ,  G01N21/64 ,  G01N35/00 ,  G01N35/10

CPC classification number: C12N15/1013 ,  B01L7/52 ,  G01N21/6428 ,  G01N35/00732 ,  G01N35/0099 ,  G01N35/1002 ,  G01N35/1079 ,  B01L2200/0647 ,  B01L2200/16 ,  B01L2300/021 ,  B01L2300/041 ,  B01L2300/0663 ,  B01L2300/1805 ,  B01L2300/1894 ,  G01N2021/6439 ,  G01N2035/00752 ,  G01N2201/08

Abstract: A DNA and RNA nucleic acid co-extraction and detection system includes a nucleic acid extraction system, a sealing, transferring and mixing system, a nucleic acid detection system and a control system, wherein the nucleic acid extraction system, the sealing, transferring and mixing system and the nucleic acid detection system are all connected to the control system; the nucleic acid extraction system comprises a carry basket for loading an extraction reagent strip and a sample tube, a consumable-material supply module, a reagent kit loading module, a barcode scanning device for automatically inputting barcode information, a magnetic absorption incubation device, and an automatic sample addition device for transferring a liquid to a reaction chamber of the extraction reagent strip or a PCR tube and sealing the PCR tube; the sealing and transferring system comprises a PCR transferring device for grabbing and driving a PCR tube to move, and a high-speed mixing device.

公开(公告)号：US12019001B2

公开(公告)日：2024-06-25

申请号：US17959109

申请日：2022-10-03

Applicant: LEICA BIOSYSTEMS MELBOURNE PTY LTD

Inventor： Zbigniew Mioduszewski ,  Aaron Ridgway ,  Matthew King ,  Blake Hellard

IPC: G01N1/00 ,  G01N1/31 ,  G01N35/00 ,  G01N35/10

CPC classification number: G01N1/312 ,  G01N35/00029 ,  G01N35/1002 ,  G01N35/1004 ,  G01N35/1072 ,  G01N35/1081 ,  G01N2035/00059 ,  G01N2035/00138

Abstract: The present invention relates to a fluid transport system for an automated slide treatment apparatus for treating one or more tissue samples disposed on slides, whereby the slide treatment apparatus includes a plurality of slide treatment modules arranged to receive ones of the slides, and the fluid transport system includes a fluid dispensing robot configured by a controller to dispense a plurality of reagents to said ones of the slides received in the slide treatment modules to treat said one or more tissue samples respectively.

公开(公告)号：US20240201218A1

公开(公告)日：2024-06-20

申请号：US18555737

申请日：2022-01-27

Applicant: Hitachi High-Tech Corporation

Inventor： Mayuko ITO ,  Shinya MATSUOKA

IPC: G01N35/10

CPC classification number: G01N35/1004 ,  G01N35/1002

Abstract: Provided is an automatic analyzer capable of preventing precipitation of a solute in a cleaning liquid in a reservoir used for cleaning a dispensing probe. The automatic analyzer for analyzing a sample includes a dispensing probe configured to dispense the sample or a reagent, a reservoir configured to reserve a cleaning liquid used for cleaning the dispensing probe, a flow path connected to the reservoir and through which the cleaning liquid flows, and a control unit configured to control each unit. The control unit draws the cleaning liquid in the reservoir into the flow path, and then supplies system water to the reservoir.

公开(公告)号：US20240192240A1

公开(公告)日：2024-06-13

申请号：US18531853

申请日：2023-12-07

Applicant: CANON MEDICAL SYSTEMS CORPORATION

Inventor： Takeshi KINPARA ,  Takafumi FUJIWARA ,  Takahiro OMORI ,  Hideto KOJIMA ,  Yoshifumi YAMAGATA ,  Tomoaki KURANO

IPC: G01N35/02 ,  G01N35/00 ,  G01N35/10

CPC classification number: G01N35/026 ,  G01N35/00663 ,  G01N35/00732 ,  G01N35/1002 ,  G01N35/1009 ,  G01N2035/00673 ,  G01N2035/1025

Abstract: A transport rack according to the present embodiment comprises a holder configured to hold a storage container that stores a sample or a reagent that is reacted with the sample, a first observation window configured to enable reading of identification information on the storage container, and a second observation window configured to enable observation of the sample or the reagent stored in the storage container.