公开(公告)号：US20080009835A1

公开(公告)日：2008-01-10

申请号：US11353762

申请日：2006-02-13

申请人： Marshall Kriesel ,  Joshua Kriesel ,  Alan Langerud

发明人： Marshall Kriesel ,  Joshua Kriesel ,  Alan Langerud

IPC分类号： A61K9/22

CPC分类号： A61M5/152 ,  A61M5/141 ,  A61M5/14244 ,  A61M5/16813 ,  A61M5/16881 ,  A61M5/24 ,  A61M5/2429 ,  A61M5/2466 ,  A61M5/3146 ,  A61M5/315 ,  A61M2005/1402 ,  A61M2005/3104 ,  A61M2005/3121 ,  A61M2005/3139

摘要： An apparatus for delivering fluids at precisely controlled rates to ambulatory patients. The invention comprises a housing having a fluid reservoir to contain fluids to be delivered to the patient, a novel stored energy membrane for expelling fluid from the reservoir and a unique flow control assembly in communication with the fluid reservoir for the precise infusion of pharmaceutical fluids to ambulatory patients at precisely controlled rates. The flow control assembly includes a novel rate control member having a plurality of fluidic micro-channels through which the fluid is selectively directed.

摘要翻译： 用于以精确控制的速率向流动患者输送流体的装置。 本发明包括具有流体储存器以容纳要输送到患者的流体的壳体，用于从储存器排出流体的新型存储的能量膜和与流体储存器连通以将药物流体精确地输注到 门诊患者精确控制率。 流量控制组件包括具有多个流体微通道的新颖的速率控制构件，流体被选择性地引导通过。

公开(公告)号：US20060196552A1

公开(公告)日：2006-09-07

申请号：US11353598

申请日：2006-02-13

申请人： Marshall Kriesel ,  Joshua Kriesel ,  Alan Langerud ,  Donald Bivin

发明人： Marshall Kriesel ,  Joshua Kriesel ,  Alan Langerud ,  Donald Bivin

IPC分类号： G05D7/06

CPC分类号： A61M5/141 ,  A61M5/16804 ,  B01L3/502746 ,  F16K99/0001 ,  F16K99/0013 ,  F16K99/0028 ,  G05D7/0186 ,  Y10T137/7256 ,  Y10T137/7761 ,  Y10T137/8275

摘要： A distal rate control device, which can be conveniently interposed between a fluid supply line and fluid delivery line for precisely controlling the rate of fluid flow toward the delivery line. The device includes a readily adjustable flow rate control device having a novel flow control plate that can be placed in fluid communication with the fluid supply line and with the fluid delivery line. The flow control plate is provided with a plurality of elongated fluidic flow control channels that are in communication with a rate selector member that is rotatably carried by the device housing. Rotation of the rate selector member places a selected one of the flow control channels in communication with the fluid delivery line.

摘要翻译： 远程速率控制装置，其可以方便地插入在流体供应管线和流体输送管线之间，用于精确地控制流向输送管线的流体流速。 该装置包括易于调节的流量控制装置，其具有新颖的流量控制板，其可以被放置成与流体供应管线和流体输送管线流体连通。 流量控制板设置有多个细长的流体流动控制通道，其与由装置壳体可旋转地承载的速率选择器构件连通。 速率选择器构件的旋转将所选择的一个流量控制通道与流体输送管线连通。

公开(公告)号：US20060206052A1

公开(公告)日：2006-09-14

申请号：US11353593

申请日：2006-02-13

申请人： Marshall Kriesel ,  Joshua Kriesel ,  Alan Langerud

发明人： Marshall Kriesel ,  Joshua Kriesel ,  Alan Langerud

IPC分类号： A61M37/00

CPC分类号： A61M5/16827 ,  A61M5/1408 ,  A61M5/141 ,  A61M5/14244 ,  A61M5/14566 ,  A61M5/2429 ,  A61M2209/045

摘要： A dual reservoir fluid dispensing apparatus for use in controllably dispensing fluid medicaments, such as antibiotics, analgesics and like medicinal agents from either or both of the device reservoirs. The fluid dispensing apparatus includes novel fill means for selectively filling each of the reservoirs with the same or different medicaments that are to be dispensed to the patent. Stored energy sources are provided in the form of a pair of constant force spring members of novel design that provide the force necessary to continuously and substantially uniformly expel fluid from the reservoirs. The apparatus also includes novel adjustable flow rate assemblies that are disposed intermediate the outlet port of the fluid reservoirs and the outlet port of the device for precisely controlling the rate of fluid flow from the outlet port toward the patient.

摘要翻译： 一种双储存器流体分配装置，用于可控地分配流体药物，例如来自装置储存器中的一个或两个的抗生素，止痛剂和类似药剂。 流体分配装置包括新颖的填充装置，用于用要分配给专利的相同或不同的药剂选择性地填充每个储存器。 存储的能源以新颖设计的一对恒力弹簧构件的形式提供，其提供连续地且基本上均匀地从储层排出流体所需的力。 该装置还包括设置在流体储存器的出口和装置的出口之间的新颖的可调流量组件，用于精确地控制从出口朝向患者的流体流速。

公开(公告)号：US20060041077A1

公开(公告)日：2006-02-23

申请号：US11202322

申请日：2005-08-10

申请人： Joshua Kriesel ,  Donald Bivin ,  David Olson ,  Jeremy Harris

发明人： Joshua Kriesel ,  Donald Bivin ,  David Olson ,  Jeremy Harris

IPC分类号： C08F120/08

CPC分类号： C08F8/30

摘要： Nanofilms useful for filtration are prepared from amphiphilic species and one or more polymeric components. The amphiphilic species or components may be oriented on an interface or surface. A nanofilm may be prepared by coupling one or more of the components. The nanofilm may also be deposited or attached to a substrate.

摘要翻译： 用于过滤的纳米薄膜由两亲物质和一种或多种聚合物组分制备。 两亲性物质或组分可以在界面或表面上取向。 可以通过偶联一种或多种组分来制备纳米薄膜。 纳米薄膜也可以沉积或附着到基底上。

公开(公告)号：US20060195057A1

公开(公告)日：2006-08-31

申请号：US11353761

申请日：2006-02-13

申请人： Marshall Kriesel ,  Joshua Kriesel ,  Alan Langerud

发明人： Marshall Kriesel ,  Joshua Kriesel ,  Alan Langerud

IPC分类号： A61N1/30

CPC分类号： A61M5/141 ,  A61M5/14244 ,  A61M5/148 ,  A61M5/16813 ,  A61M2005/1402 ,  A61M2005/1403 ,  A61M2005/14506 ,  A61M2209/045

摘要： A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, analgesics, and the like medicinal agents from the reservoir of the device. Uniquely, the dispenser includes a novel bellows-type reservoir and vial fill means for filling the bellows-type reservoir with the medicament to be dispensed. The dispenser also includes a novel stored energy source in the form of a constant force spring which controllably urges the medicinal fluid from the device reservoir. Additionally, the apparatus of the invention includes a novel adjustable flow rate control assembly that is disposed intermediate the fluid reservoir outlet and the outlet port of the device for precisely controlling the rate of fluid flow from the outlet port toward the patient. The rate control assembly includes a rate selector member for selecting the desired rate of fluid flow toward the patient and a cooperatively associated flow control plate having a plurality of fluidic micro-channels which controls the rate of fluid flow toward the selector member. The rate control plate uniquely includes a priming feature for priming the various fluid passageways of the device and purging the fluid passageways of gases that may be contained therein prior to the delivery of the medicinal fluids to the administration line of the device.

摘要翻译： 一种紧凑的流体分配器，用于从装置的储存器中可控地分配流体药物，例如抗生素，止痛剂等药物。 独特地，分配器包括新颖的波纹管式储存器和用于用要分配的药物填充波纹管式储存器的小瓶填充装置。 分配器还包括以恒力弹簧的形式的新颖的储存能源，其可控制地从装置储存器推动药液。 另外，本发明的装置包括一个新颖的可调节流量控制组件，其设置在装置的流体储存器出口和出口的中间，用于精确地控制从出口朝向患者的流体流速。 速率控制组件包括用于选择朝向患者的流体流量的期望速率的速率选择器构件和具有多个流体微通道的协作关联的流量控制板，其控制流向选择器构件的流体流速。 速率控制板唯一地包括起动特征，用于在将药液输送到装置的管理线之前，灌注装置的各种流体通道并清洗可能包含在其中的气体的流体通道。

公开(公告)号：US20050277884A1

公开(公告)日：2005-12-15

申请号：US10855446

申请日：2004-05-26

申请人： Marshall Kriesel ,  Joshua Kriesel

发明人： Marshall Kriesel ,  Joshua Kriesel

IPC分类号： A61M5/14 ,  A61M5/145 ,  A61M5/148 ,  A61M5/168 ,  A61M5/50 ,  B67D1/00

CPC分类号： A61M5/16877 ,  A61M5/141 ,  A61M5/148 ,  A61M5/504 ,  A61M2005/14506 ,  A61M2209/045

摘要： A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as, antibiotics, analgesics, and like medicinal agents from the device reservoir which is provided in the form of a novel bellows type assembly. The fluid dispenser includes a unique stored energy mechanism which takes the form of a constant force spring member of novel design that provides the force necessary to continuously and substantially uniformly expel fluid from the device reservoir. The device also includes novel adjustable flow rate control assembly that is disposed intermediate the fluid reservoir outlet and the outlet port of the device for precisely controlling the rate of fluid flow from the outlet port toward the patient.

摘要翻译： 用于可控地分配液体药物的紧凑型流体分配器，例如来自设备储存器的抗生素，止痛剂和类似药剂，其以新型波纹管式组件的形式提供。 流体分配器包括独特的存储能量机构，其采用新颖设计的恒力弹簧构件的形式，其提供连续且基本均匀地排出来自装置储存器的流体所需的力。 该装置还包括新颖的可调节流量控制组件，其设置在装置的流体储存器出口和出口的中间，用于精确地控制从出口朝向患者的流体流速。

公开(公告)号：US20050154199A1

公开(公告)日：2005-07-14

申请号：US10913634

申请日：2004-08-06

申请人： Jeffery Whiteford ,  William Freeman ,  Joshua Kriesel

发明人： Jeffery Whiteford ,  William Freeman ,  Joshua Kriesel

IPC分类号： C07D20060101 ,  C07D487/22 ,  C07D491/14 ,  C07K1/10

CPC分类号： C07D273/00 ,  C07D498/18 ,  C07D513/18

摘要： This invention is related to the fields of organic chemistry and nanotechnology. In particular, it relates to materials and methods for the preparation of organic synthons and bridged macrocyclic module compounds. The bridged macrocyclic module compounds may be used to prepare macrocyclic compositions such as nanofilms, which may be useful for filtration.

摘要翻译： 本发明涉及有机化学和纳米技术领域。 特别涉及制备有机合成物和桥连大环模块化合物的材料和方法。 桥联的大环模块化合物可用于制备大环组合物，例如可用于过滤的纳米薄膜。

公开(公告)号：US20050263615A1

公开(公告)日：2005-12-01

申请号：US10854830

申请日：2004-05-26

申请人： Marshall Kriesel ,  Joshua Kriesel

发明人： Marshall Kriesel ,  Joshua Kriesel

IPC分类号： A61M5/00 ,  A61M5/145 ,  A61M5/168

CPC分类号： A61M5/1454 ,  A61M5/16877

摘要： A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as, antibiotics, analgesics, and like medicinal agents from the device reservoir. The fluid dispenser includes a unique stored energy mechanism which takes the form of a constant force spring member of novel design that provides the force necessary to continuously and substantially uniformly expel fluid from the device reservoir. The device also includes novel adjustable flow rate control assembly that is disposed intermediate the fluid reservoir outlet and the outlet port of the device for precisely controlling the rate of fluid flow from the outlet port toward the patient.

摘要翻译： 用于可控地分配来自装置储存器的流体药物例如抗生素，止痛剂和类似药剂的紧凑型流体分配器。 流体分配器包括独特的存储能量机构，其采用新颖设计的恒力弹簧构件的形式，其提供连续且基本均匀地排出来自装置储存器的流体所需的力。 该装置还包括新颖的可调节流量控制组件，其设置在装置的流体储存器出口和出口的中间，用于精确地控制从出口朝向患者的流体流速。