Means and methods for treating DLBCL
    1.
    发明授权
    Means and methods for treating DLBCL 有权
    治疗DLBCL的方法和方法

    公开(公告)号:US09192665B2

    公开(公告)日:2015-11-24

    申请号:US13881889

    申请日:2011-10-27

    摘要: The present invention provides means and methods for treating diffuse large B cell lymphoma (DLBCL). Specifically, a bispecific CD19×CD3 antibody which engages T cells via its CD3 binding portion and concomitantly binds to CD19 on the surface of in particular, lymphoma cells via its CD19 binding portion (i.e. a bispecific T cell engager, “BiTE”) is administered for use in the treatment of tumorous mass of lymophoreticular tissue and/or extranodal lymphoma caused by DLBCL in a patient.

    摘要翻译: 本发明提供了治疗弥漫性大B细胞淋巴瘤(DLBCL)的方法和方法。 具体地,施用通过其CD3结合部分与T细胞接合并通过其CD19结合部分特别是淋巴瘤细胞表面(即,双特异性T细胞募集体“BiTE”)同时结合CD19的双特异性CD19×CD3抗体) 用于治疗由DLBCL引起的淋巴管组织和/或结外淋巴瘤的肿瘤组织。

    LOW TEMPERATURE FUSE
    2.
    发明申请
    LOW TEMPERATURE FUSE 审中-公开
    低温保险丝

    公开(公告)号:US20090189730A1

    公开(公告)日:2009-07-30

    申请号:US12362913

    申请日:2009-01-30

    IPC分类号: H01H85/04

    摘要: A fuse is disclosed, the fuse made of a first metal, such as copper, and having a notched portion with an alloying element, such as tin, deposited in the notch. The alloying element helps to lower the voltage drop across the notch, allowing the fuse to generate less heat during operation without affecting its ability to protect a circuit to which it is connected. The fuse may also include a housing and terminals to connect into a circuit.

    摘要翻译: 公开了一种保险丝,由诸如铜的第一金属制成的保险丝,并且具有凹陷部分,该凹槽部分具有沉积在凹口中的诸如锡的合金元素。 合金元素有助于降低切口两端的电压降,允许熔断器在运行过程中产生较少的热量,而不会影响其保护与其连接的电路的能力。 保险丝还可以包括用于连接到电路中的外壳和端子。

    Blade fuse
    3.
    发明授权
    Blade fuse 有权
    刀片保险丝

    公开(公告)号:US08976000B2

    公开(公告)日:2015-03-10

    申请号:US13287660

    申请日:2011-11-02

    摘要: A blade fuse includes a first terminal includes an outer edge and an inner edge, the inner edge includes a first portion notched away from the inner edge beneath the first portion; a second terminal includes an outer edge and an inner edge, the inner edge include a second portion notched away from the inner edge beneath the second portion; an element extending from the first portion of the inner edge of the first terminal to the second portion of the inner edge of the second terminal; and a housing covering the element.

    摘要翻译: 叶片保险丝包括第一端子,其包括外边缘和内边缘,所述内边缘包括从第一部分下方的内边缘切开的第一部分; 第二端子包括外边缘和内边缘,所述内边缘包括从所述第二部分下方的所述内边缘切开的第二部分; 从第一端子的内边缘的第一部分延伸到第二端子的内边缘的第二部分的元件; 以及覆盖该元件的壳体。

    BLADE FUSE
    5.
    发明申请
    BLADE FUSE 审中-公开
    刀片保险丝

    公开(公告)号:US20120044037A1

    公开(公告)日:2012-02-23

    申请号:US13287660

    申请日:2011-11-02

    IPC分类号: H01H85/02

    摘要: A blade fuse includes a first terminal includes an outer edge and an inner edge, the inner edge includes a first portion notched away from the inner edge beneath the first portion; a second terminal includes an outer edge and an inner edge, the inner edge include a second portion notched away from the inner edge beneath the second portion; an element extending from the first portion of the inner edge of the first terminal to the second portion of the inner edge of the second terminal; and a housing covering the element.

    摘要翻译: 叶片保险丝包括第一端子,其包括外边缘和内边缘,所述内边缘包括从第一部分下方的内边缘切开的第一部分; 第二端子包括外边缘和内边缘,所述内边缘包括从所述第二部分下方的所述内边缘切开的第二部分; 从第一端子的内边缘的第一部分延伸到第二端子的内边缘的第二部分的元件; 以及覆盖该元件的壳体。

    Blade fuse
    6.
    发明授权
    Blade fuse 有权
    刀片保险丝

    公开(公告)号:US08077007B2

    公开(公告)日:2011-12-13

    申请号:US12013997

    申请日:2008-01-14

    IPC分类号: H01H85/08 H01H85/02

    摘要: A blade fuse includes a first terminal includes an outer edge and an inner edge, the inner edge includes a first portion notched away from the inner edge beneath the first portion; a second terminal includes an outer edge and an inner edge, the inner edge include a second portion notched away from the inner edge beneath the second portion; an element extending from the first portion of the inner edge of the first terminal to the second portion of the inner edge of the second terminal; and a housing covering the element.

    摘要翻译: 叶片保险丝包括第一端子,其包括外边缘和内边缘,所述内边缘包括从第一部分下方的内边缘切开的第一部分; 第二端子包括外边缘和内边缘,所述内边缘包括从所述第二部分下方的所述内边缘切开的第二部分; 从第一端子的内边缘的第一部分延伸到第二端子的内边缘的第二部分的元件; 以及覆盖该元件的壳体。

    Flexible power distribution module
    7.
    发明授权
    Flexible power distribution module 有权
    灵活配电模块

    公开(公告)号:US07955133B2

    公开(公告)日:2011-06-07

    申请号:US12108328

    申请日:2008-04-23

    IPC分类号: H01R13/68 H02B1/26

    摘要: A power distribution module for a vehicle includes an insulating housing including a component grid, the component grid defining a plurality of circuit protection footprints, the housing further including at least one connector mount or terminal mating location; a printed circuit board (“PCB”) located within the housing and beneath the component grid, the PCB holding a plurality of fuse mounting terminals and at least one connector mounting terminal, the PCB including a plurality of conducting traces connecting the fuse mounting terminals to the at least one connector mounting terminal; and a cover that threadingly engages the housing, the threading engagement leading to a locking of the cover to the housing that tends to prevent the cover from loosening from the housing when the vehicle is being driven, the locking of the cover able to be overcome by a person so that the cover can be unthreaded readily from the housing.

    摘要翻译: 一种用于车辆的配电模块包括:绝缘壳体,其包括部件网格,所述部件网格限定多个电路保护贴片,所述壳体还包括至少一个连接器安装件或端子配合位置; 一个印刷电路板(“PCB”),位于壳体内部和元件栅格之下,PCB保持着多个保险丝安装端子和至少一个连接器安装端子,该PCB包括多个连接熔断器安装端子的导电迹线 所述至少一个连接器安装端子; 以及与所述壳体螺纹接合的盖,所述螺纹接合导致所述盖到所述壳体的锁定,所述盖倾向于防止所述盖在所述车辆被驱动时从所述壳体松动,所述盖的锁定能够被 一个人,使得盖子可以容易地从壳体上撕开。

    MEANS AND METHODS FOR TREATING DLBCL
    8.
    发明申请
    MEANS AND METHODS FOR TREATING DLBCL 有权
    治疗DLBCL的方法和方法

    公开(公告)号:US20130287778A1

    公开(公告)日:2013-10-31

    申请号:US13881889

    申请日:2011-10-27

    IPC分类号: A61K39/395

    摘要: The present invention provides means and methods for treating diffuse large B cell lymphoma (DLBCL). Specifically, a bispecific CD19×CD3 antibody which engages T cells via its CD3 binding portion and concomitantly binds to CD19 on the surface of in particular, lymphoma cells via its CD19 binding portion (i.e. a bispecific T cell engager, “BiTE”) is administered for use in the treatment of tumorous mass of lymophoreticular tissue and/or extranodal lymphoma caused by DLBCL in a patient.

    摘要翻译: 本发明提供了治疗弥漫性大B细胞淋巴瘤(DLBCL)的方法和方法。 具体地,施用通过其CD3结合部分与T细胞接合并通过其CD19结合部分特别是淋巴瘤细胞表面(即双特异性T细胞募集体“BiTE”)并与CD19结合的双特异性CD19×CD3抗体) 用于治疗由DLBCL引起的淋巴管组织和/或结外淋巴瘤的肿瘤组织。