利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

180 条记录 (耗时 0.031 秒)

    Intermittent high-energy cardiac stimulation for therapeutic effect
    1.
    发明授权
    Intermittent high-energy cardiac stimulation for therapeutic effect 有权
    间歇性高能心脏刺激治疗效果

    公开(公告)号：US09037233B2

    公开(公告)日：2015-05-19

    申请号：US12838792

    申请日：2010-07-19

    申请人： Joseph M. Pastore ,  Imad Libbus ,  Andrew P. Kramer ,  Julio C. Spinelli

    发明人： Joseph M. Pastore ,  Imad Libbus ,  Andrew P. Kramer ,  Julio C. Spinelli

    IPC分类号： A61N1/00 ,  A61N1/362

    CPC分类号： A61N1/3627 ,  A61N1/3622

    摘要： A device and method for delivering high-energy electrical stimulation to the heart in order to improve cardiac function in heart failure patients. The high-energy stimulation mimics the effects of exercise and improves symptoms even in patients who are exercise intolerant. The high-energy stimulation may be delivered on an intermittent basis either as pacing pulses in accordance with a programmed pacing mode and with a higher pacing pulse energy than used for conventional pacing or as low energy shock pulses.

    摘要翻译： 用于向心脏递送高能电刺激以改善心力衰竭患者的心脏功能的装置和方法。 高能量刺激模拟运动的影响，即使在运动不耐受的患者中也能改善症状。 高能量刺激可以间歇地作为起搏脉冲递送，或者作为起搏脉冲根据编程的起搏模式和较高的起搏脉冲能量而不是用于常规起搏或低能量冲击脉冲。

    Closed loop impedance-based cardiac resynchronization therapy systems, devices, and methods
    4.
    发明授权
    Closed loop impedance-based cardiac resynchronization therapy systems, devices, and methods 有权
    基于闭环阻抗的心脏再同步治疗系统，装置和方法

    公开(公告)号：US08295927B2

    公开(公告)日：2012-10-23

    申请号：US12254631

    申请日：2008-10-20

    申请人： Jiang Ding ,  Yinghong Yu ,  Julio C. Spinelli ,  Jeffrey E. Stahmann

    发明人： Jiang Ding ,  Yinghong Yu ,  Julio C. Spinelli ,  Jeffrey E. Stahmann

    IPC分类号： A61N1/365

    CPC分类号： A61N1/3627 ,  A61B5/053 ,  A61N1/36521 ,  A61N1/3682 ,  A61N1/3684

    摘要： This document discusses, among other things, systems, devices, and methods measure an impedance and, in response, adjust an atrioventricular (AV) delay or other cardiac resynchronization therapy (CRT) parameter that synchronizes left and right ventricular contractions. A first example uses parameterizes a first ventricular volume against a second ventricular volume during a cardiac cycle, using a loop area to create a synchronization fraction (SF). The CRT parameter is adjusted in closed-loop fashion to increase the SF. A second example measures a septal-freewall phase difference (PD), and adjusts a CRT parameter to decrease the PD. A third example measures a peak-to-peak volume or maximum rate of change in ventricular volume, and adjusts a CRT parameter to increase the peak-to-peak volume or maximum rate of change in the ventricular volume.

    摘要翻译： 本文件还讨论了系统，设备和方法测量阻抗，并作为响应调整房室（AV）延迟或同步左心室收缩和右心室收缩的其他心脏再同步治疗（CRT）参数。 第一个例子是使用循环区域创建同步分数（SF），在心动周期中使用第一心室容积对第二心室容积进行参数化。 CRT参数以闭环方式调整以增加SF。 第二个例子是测量隔层相位差（PD），并调整CRT参数以减少PD。 第三个例子测量峰 - 峰体积或最大心室容积变化率，并调整CRT参数以增加心室容积的峰 - 峰体积或最大变化率。

    Method and apparatus for determining the coronary sinus vein branch accessed by a coronary sinus lead
    6.
    发明授权
    Method and apparatus for determining the coronary sinus vein branch accessed by a coronary sinus lead 有权
    用于确定冠状静脉窦导管接近的冠状静脉窦静脉分支的方法和装置

    公开(公告)号：US08214026B2

    公开(公告)日：2012-07-03

    申请号：US12976397

    申请日：2010-12-22

    申请人： Yinghong Yu ,  Jiang Ding ,  Jeng Mah ,  Julio C. Spinelli

    发明人： Yinghong Yu ,  Jiang Ding ,  Jeng Mah ,  Julio C. Spinelli

    IPC分类号： A61B5/0452

    CPC分类号： A61B5/0452 ,  A61B5/0456 ,  A61B34/20 ,  A61B2034/2072 ,  A61N1/3627 ,  A61N1/3682

    摘要： Systems and methods for determining the coronary sinus vein branch location of a left ventricle electrode are disclosed. The systems and methods involve detecting the occurrence of electrical events within the patient's heart including sensing one or more of the electrical events with the electrode and then analyzing the electrical events to determine the electrode's position. The determination of electrode position may be used to automatically adjust operating parameters of a VRT device. Furthermore, the determination of electrode position may be made in real-time during installation of the electrode and a visual indication of the electrode position may be provided on a display screen.

    摘要翻译： 公开了用于确定左心室电极的冠状静脉窦静脉分支位置的系统和方法。 系统和方法涉及检测患者心脏内的电事件的发生，包括用电极感测一个或多个电事件，然后分析电气事件以确定电极的位置。 电极位置的确定可用于自动调整VRT器件的工作参数。 此外，可以在电极的安装期间实时地确定电极位置，并且可以在显示屏上提供电极位置的视觉指示。

    Cardiac rhythm management system selecting between multiple same-chamber electrodes for delivering cardiac therapy
    7.
    发明授权
    Cardiac rhythm management system selecting between multiple same-chamber electrodes for delivering cardiac therapy 有权
    心脏节律管理系统选择多个相同室电极之间进行心脏治疗

    公开(公告)号：US08121686B2

    公开(公告)日：2012-02-21

    申请号：US13026917

    申请日：2011-02-14

    申请人： Jiang Ding ,  Julio C. Spinelli ,  Andrew P. Kramer

    发明人： Jiang Ding ,  Julio C. Spinelli ,  Andrew P. Kramer

    IPC分类号： A61N1/362

    CPC分类号： A61N1/3684 ,  A61N1/3627 ,  A61N1/36514 ,  A61N1/368

    摘要： A cardiac rhythm management system selects one of multiple electrodes associated with a particular heart chamber based on a relative timing between detection of a depolarization fiducial point at the multiple electrodes, or based on a delay between detection of a depolarization fiducial point at the multiple electrodes and detection of a reference depolarization fiducial point at another electrode associated with the same or a different heart chamber. Subsequent contraction-evoking stimulation therapy is delivered from the selected electrode.

    摘要翻译： 心脏节律管理系统基于在多个电极处的去极化基准点的检测之间的相对定时或基于在多个电极之间的去极化基准点的检测之间的延迟来选择与特定心室相关联的多个电极中的一个，以及 在与相同或不同的心室相关联的另一电极处检测参考去极化基准点。 随后的收缩诱导刺激疗法从所选择的电极递送。

    REDUCTION OF AV DELAY FOR TREATMENT OF CARDIAC DISEASE
    10.
    发明申请
    REDUCTION OF AV DELAY FOR TREATMENT OF CARDIAC DISEASE 有权
    减少AV延迟治疗心脏病

    公开(公告)号：US20110319955A1

    公开(公告)日：2011-12-29

    申请号：US13229948

    申请日：2011-09-12

    申请人： Joseph M. Pastore ,  Rodney W. Salo ,  Julio C. Spinelli ,  Allan C. Shuros ,  Andres Belalcazar

    发明人： Joseph M. Pastore ,  Rodney W. Salo ,  Julio C. Spinelli ,  Allan C. Shuros ,  Andres Belalcazar

    IPC分类号： A61N1/365

    CPC分类号： A61N1/3627 ,  A61N1/36521 ,  A61N1/36535 ,  A61N1/36542 ,  A61N1/36564 ,  A61N1/3688

    摘要： An implantable pacing device for delivering ventricular pacing may be configured to intermittently reduce the AVD interval for beneficial effect in patients with compromised ventricular function (e.g., HF patients and post-MI patients). The AVD interval may be reduced in an AVD reduction mode, by shortening the AVD in an atrial triggered ventricular pacing mode or by switching to a non-atrial triggered ventricular pacing mode (e.g., VVI) and delivering paces at a rate above the intrinsic rate. The physiological effects of AVD reduction may be either positive or negative on cardiac output, depending upon the individual patient.

    摘要翻译： 用于输送心室起搏的可植入起搏装置可以被配置为间歇地减小AVD间隔，以在患有心室功能受损的患者（例如，HF患者和MI后患者）中产生有益效果。 通过在心房触发的心室起搏模式中缩短AVD或者通过切换到非心房触发的心室起搏模式（例如，VVI）并以高于内在速率的速率递送步进，AVD间期可以减小AVD减小模式 。 取决于个体患者，AVD减少的生理作用可能是心输出量的正或负。