公开(公告)号：US20120202272A1

公开(公告)日：2012-08-09

申请号：US13220658

申请日：2011-08-29

Applicant: Ranjini Chatterjee ,  Kenneth Zahn ,  Kenneth Mitchell ,  Yaoquan Liu

Inventor： Ranjini Chatterjee ,  Kenneth Zahn ,  Kenneth Mitchell ,  Yaoquan Liu

IPC: C12N1/21

CPC classification number: C12N9/1088 ,  C12N9/88 ,  C12P7/22 ,  C12P7/26 ,  C12P7/42 ,  C12Y205/01018

Abstract: The teachings provided herein are generally directed to a method of converting lignin-derived compounds to valuable aromatic chemicals using an enzymatic, bioconversion process. The teachings provide a selection of (i) host cells that are tolerant to the toxic compounds present in lignin fractions; (ii) polypeptides that can be used as enzymes in the bioconversion of the lignin fractions to the aromatic chemical products; (iii) polynucleotides that can be used to transform the host cells to express the selection of polypeptides as enzymes in the bioconversion of the lignin fractions; and (iv) the transformants that express the enzymes.

Abstract translation: 本文提供的教导通常涉及使用酶促生物转化过程将木质素衍生的化合物转化为有价值的芳族化学品的方法。 该教导提供（i）对木质素部分中存在的有毒化合物具有耐受性的宿主细胞的选择; （ii）在木质素部分生物转化成芳族化学产品时可用作酶的多肽; （iii）可用于转化宿主细胞以表达多肽选择的多核苷酸，作为木质素级分的生物转化中的酶; 和（iv）表达酶的转化体。

公开(公告)号：US20120202258A1

公开(公告)日：2012-08-09

申请号：US13220646

申请日：2011-08-29

Applicant: Ranjini Chatterjee ,  Kenneth Zahn ,  Kenneth Mitchell ,  Yaoquan Liu

Inventor： Ranjini Chatterjee ,  Kenneth Zahn ,  Kenneth Mitchell ,  Yaoquan Liu

IPC: C12P13/00 ,  C12N15/63 ,  C12P7/42 ,  C12P7/22 ,  C12P7/24 ,  C12N15/54 ,  C12N1/21

CPC classification number: C12N9/1088 ,  C12N9/88 ,  C12P7/22 ,  C12P7/26 ,  C12P7/42 ,  C12Y205/01018

Abstract: The teachings provided herein are generally directed to a method of converting lignin-derived compounds to valuable aromatic chemicals using an enzymatic, bioconversion process. The teachings provide a selection of (i) host cells that are tolerant to the toxic compounds present in lignin fractions; (ii) polypeptides that can be used as enzymes in the bioconversion of the lignin fractions to the aromatic chemical products; (iii) polynucleotides that can be used to transform the host cells to express the selection of polypeptides as enzymes in the bioconversion of the lignin fractions; and (iv) the transformants that express the enzymes.

Abstract translation: 本文提供的教导通常涉及使用酶促生物转化过程将木质素衍生的化合物转化为有价值的芳族化学品的方法。 该教导提供（i）对木质素部分中存在的有毒化合物具有耐受性的宿主细胞的选择; （ii）在木质素部分生物转化成芳族化学产品时可用作酶的多肽; （iii）可用于转化宿主细胞以表达多肽选择的多核苷酸，作为木质素级分的生物转化中的酶; 和（iv）表达酶的转化体。

公开(公告)号：US20130143304A9

公开(公告)日：2013-06-06

申请号：US13220662

申请日：2011-08-29

Applicant: RANJINI CHATTERJEE ,  KENNETH ZAHN ,  KENNETH MITCHELL ,  YAOQUAN LIU

Inventor： RANJINI CHATTERJEE ,  KENNETH ZAHN ,  KENNETH MITCHELL ,  YAOQUAN LIU

IPC: C12N1/21

CPC classification number: C12N9/1088 ,  C12N9/88 ,  C12P7/22 ,  C12P7/26 ,  C12P7/42 ,  C12Y205/01018

Abstract: The teachings provided herein are generally directed to a method of converting lignin-derived compounds to valuable aromatic chemicals using an enzymatic, bioconversion process. The teachings provide a selection of (i) host cells that are tolerant to the toxic compounds present in lignin fractions; (ii) polypeptides that can be used as enzymes in the bioconversion of the lignin fractions to the aromatic chemical products; (iii) polynucleotides that can be used to transform the host cells to express the selection of polypeptides as enzymes in the bioconversion of the lignin fractions; and (iv) the transformants that express the enzymes.

Abstract translation: 本文提供的教导通常涉及使用酶促生物转化过程将木质素衍生的化合物转化为有价值的芳族化学品的方法。 该教导提供（i）对木质素部分中存在的有毒化合物具有耐受性的宿主细胞的选择; （ii）在木质素部分生物转化成芳族化学产品时可用作酶的多肽; （iii）可用于转化宿主细胞以表达多肽选择的多核苷酸，作为木质素级分的生物转化中的酶; 和（iv）表达酶的转化体。

公开(公告)号：US20120196353A1

公开(公告)日：2012-08-02

申请号：US13220662

申请日：2011-08-29

Applicant: RANJINI CHATTERJEE ,  KENNETH ZAHN ,  KENNETH MITCHELL ,  YAOQUAN LIU

Inventor： RANJINI CHATTERJEE ,  KENNETH ZAHN ,  KENNETH MITCHELL ,  YAOQUAN LIU

IPC: C12N1/21

CPC classification number: C12N9/1088 ,  C12N9/88 ,  C12P7/22 ,  C12P7/26 ,  C12P7/42 ,  C12Y205/01018

Abstract: The teachings provided herein are generally directed to a method of converting lignin-derived compounds to valuable aromatic chemicals using an enzymatic, bioconversion process. The teachings provide a selection of (i) host cells that are tolerant to the toxic compounds present in lignin fractions; (ii) polypeptides that can be used as enzymes in the bioconversion of the lignin fractions to the aromatic chemical products; (iii) polynucleotides that can be used to transform the host cells to express the selection of polypeptides as enzymes in the bioconversion of the lignin fractions; and (iv) the transformants that express the enzymes.

Abstract translation: 本文提供的教导通常涉及使用酶促生物转化过程将木质素衍生的化合物转化为有价值的芳族化学品的方法。 该教导提供（i）对木质素部分中存在的有毒化合物具有耐受性的宿主细胞的选择; （ii）在木质素部分生物转化成芳族化学产品时可用作酶的多肽; （iii）可用于转化宿主细胞以表达多肽选择的多核苷酸，作为木质素级分的生物转化中的酶; 和（iv）表达酶的转化体。

公开(公告)号：US20120196334A1

公开(公告)日：2012-08-02

申请号：US13220629

申请日：2011-08-29

Applicant: Ranjini Chatterjee ,  Kenneth Zahn ,  Kenneth Mitchell ,  Yaoquan Liu

Inventor： Ranjini Chatterjee ,  Kenneth Zahn ,  Kenneth Mitchell ,  Yaoquan Liu

IPC: C12N9/10 ,  C12P7/42 ,  C12P13/00 ,  C12P7/22 ,  C12P7/24

CPC classification number: C12N9/1088 ,  C12N9/88 ,  C12P7/22 ,  C12P7/26 ,  C12P7/42 ,  C12Y205/01018

Abstract: The teachings provided herein are generally directed to a method of converting lignin-derived compounds to valuable aromatic chemicals using an enzymatic, bioconversion process. The teachings provide a selection of (i) host cells that are tolerant to the toxic compounds present in lignin fractions; (ii) polypeptides that can be used as enzymes in the bioconversion of the lignin fractions to the aromatic chemical products; (iii) polynucleotides that can be used to transform the host cells to express the selection of polypeptides as enzymes in the bioconversion of the lignin fractions; and (iv) the transformants that express the enzymes.

Abstract translation: 本文提供的教导通常涉及使用酶促生物转化过程将木质素衍生的化合物转化为有价值的芳族化学品的方法。 该教导提供（i）对木质素部分中存在的有毒化合物具有耐受性的宿主细胞的选择; （ii）在木质素部分生物转化成芳族化学产品时可用作酶的多肽; （iii）可用于转化宿主细胞以表达多肽选择的多核苷酸，作为木质素级分的生物转化中的酶; 和（iv）表达酶的转化体。

公开(公告)号：US20120202257A1

公开(公告)日：2012-08-09

申请号：US13220616

申请日：2011-08-29

Applicant: Ranjini Chatterjee ,  Kenneth Zahn ,  Kenneth Mitchell ,  Yaoquan Liu

Inventor： Ranjini Chatterjee ,  Kenneth Zahn ,  Kenneth Mitchell ,  Yaoquan Liu

IPC: C12N9/10 ,  C12P7/42 ,  C12P13/00 ,  C12P7/22 ,  C12P7/24

CPC classification number: C12N9/1088 ,  C12N9/88 ,  C12P7/22 ,  C12P7/26 ,  C12P7/42 ,  C12Y205/01018

Abstract: The teachings provided herein are generally directed to a method of converting lignin-derived compounds to valuable aromatic chemicals using an enzymatic, bioconversion process. The teachings provide a selection of (i) host cells that are tolerant to the toxic compounds present in lignin fractions; (ii) polypeptides that can be used as enzymes in the bioconversion of the lignin fractions to the aromatic chemical products; (iii) polynucleotides that can be used to transform the host cells to express the selection of polypeptides as enzymes in the bioconversion of the lignin fractions; and (iv) the transformants that express the enzymes.

Abstract translation: 本文提供的教导通常涉及使用酶促生物转化过程将木质素衍生的化合物转化为有价值的芳族化学品的方法。 该教导提供（i）对木质素部分中存在的有毒化合物具有耐受性的宿主细胞的选择; （ii）在木质素部分生物转化成芳族化学产品时可用作酶的多肽; （iii）可用于转化宿主细胞以表达多肽选择的多核苷酸，作为木质素级分的生物转化中的酶; 和（iv）表达酶的转化体。

公开(公告)号：US20120196335A1

公开(公告)日：2012-08-02

申请号：US13220652

申请日：2011-08-29

Applicant: RANJINI CHATTERJEE ,  KENNETH ZAHN ,  KENNETH MITCHELL ,  YAOQUAN LIU

Inventor： RANJINI CHATTERJEE ,  KENNETH ZAHN ,  KENNETH MITCHELL ,  YAOQUAN LIU

IPC: C12N1/21 ,  C12N15/63 ,  C12P7/42 ,  C12P7/24 ,  C12P13/00 ,  C12N15/54 ,  C12P7/22

CPC classification number: C12N9/1088 ,  C12N9/88 ,  C12P7/22 ,  C12P7/26 ,  C12P7/42 ,  C12Y205/01018

Abstract: The teachings provided herein are generally directed to a method of converting lignin-derived compounds to valuable aromatic chemicals using an enzymatic, bioconversion process. The teachings provide a selection of (i) host cells that are tolerant to the toxic compounds present in lignin fractions; (ii) polypeptides that can be used as enzymes in the bioconversion of the lignin fractions to the aromatic chemical products; (iii) polynucleotides that can be used to transform the host cells to express the selection of polypeptides as enzymes in the bioconversion of the lignin fractions; and (iv) the transformants that express the enzymes.

Abstract translation: 本文提供的教导通常涉及使用酶促生物转化过程将木质素衍生的化合物转化为有价值的芳族化学品的方法。 该教导提供（i）对木质素部分中存在的有毒化合物具有耐受性的宿主细胞的选择; （ii）在木质素部分生物转化成芳族化学产品时可用作酶的多肽; （iii）可用于转化宿主细胞以表达多肽选择的多核苷酸，作为木质素级分的生物转化中的酶; 和（iv）表达酶的转化体。