公开(公告)号：US20080115593A1

公开(公告)日：2008-05-22

申请号：US11666077

申请日：2005-11-07

申请人： Kaname Mogami ,  Hiroshi Kase

发明人： Kaname Mogami ,  Hiroshi Kase

IPC分类号： G01L1/04 ,  G01N33/53 ,  C12Q1/48

CPC分类号： G01N33/6872 ,  G01N19/00 ,  G01N33/53 ,  G01N2333/4727

摘要： The object of this invention is to provide a method for detecting conformational change of calmodulin easily and simply in a short period, quantitatively and in real-time manner, and to provide a method for screening a substance having an activity that affects to conformational change of calmodulin efficiently among numerous substances. To solve the object, a method is provided and the method comprising; subjecting a test sample to be tested for its activity to a sample film comprising calmodulin, detecting change(s) in tension and/or elasticity of the sample film in comparison with prior to subjecting said test sample using a mechanochemical sensor, thereby it enables real-time and short time measurement of the activity of said test sample to induce or to inhibit conformational change of calmodulin.

摘要翻译： 本发明的目的是提供一种用于在短期内，定量和实时地容易且简单地检测钙调蛋白的构象变化的方法，并提供一种筛选具有影响构象变化的活性的物质的方法 钙调蛋白有效地在许多物质之中。 为了解决该问题，提供了一种方法，该方法包括： 将测试样品的活性测试为包含钙调蛋白的样品膜，与使用机械化学传感器处理所述测试样品之前相比，检测样品膜的张力和/或弹性变化，从而使得实际 - 时间和短时间测量所述测试样品的活性以诱导或抑制钙调蛋白的构象变化。

公开(公告)号：US09395003B2

公开(公告)日：2016-07-19

申请号：US14236884

申请日：2012-08-03

申请人： Shigeto Hayafuji ,  Takeshi Kamaya ,  Hiroshi Hayakawa ,  Yasuhiro Jinbo ,  Kaname Mogami ,  Kenji Takeshita ,  Masanori Aritomi ,  Kunio Yoshikawa ,  Saburo Kikuchi ,  Akio Ishido

发明人： Shigeto Hayafuji ,  Takeshi Kamaya ,  Hiroshi Hayakawa ,  Yasuhiro Jinbo ,  Kaname Mogami ,  Kenji Takeshita ,  Masanori Aritomi ,  Kunio Yoshikawa ,  Saburo Kikuchi ,  Akio Ishido

IPC分类号： A62D3/35 ,  F16K5/06 ,  G21F9/28 ,  G21F9/30

CPC分类号： F16K5/06 ,  G21F9/28 ,  G21F9/30

摘要： A process for reducing a radioactive material of an object containing a radioactive material to a safe level in a living environment includes releasing pressure including carrying out a heating process on an aqueous liquid that includes water, water-soluble liquid, or a mixture of water and water-soluble liquid, and the object in a state where temperature is less than or equal to a critical temperature of the aqueous liquid and pressure is greater than or equal to a saturated vapor pressure of the aqueous liquid when the object is immersed in the aqueous liquid to such a degree that the object is covered or to a greater degree and then abruptly releasing the pressure, and separating, after the releasing pressure, the mixture of the object and the aqueous liquid into liquid and solid.

摘要翻译： 一种在生活环境中将含有放射性物质的物体的放射性物质还原到安全水平的方法包括释放压力，包括对包含水，水溶性液体或水与水的混合物的水性液体进行加热处理 水溶性液体和物体在温度低于或等于水性液体的临界温度的状态下，并且当物体浸入水中时，压力大于或等于水性液体的饱和蒸气压 液体达到使物体被覆盖或者更大程度的程度，然后突然释放压力，并且在释放压力之后将物体和水性液体的混合物分离成液体和固体。

公开(公告)号：US20140228612A1

公开(公告)日：2014-08-14

申请号：US14236884

申请日：2012-08-03

申请人： Shigeto Hayafuji ,  Takeshi Kamaya ,  Hiroshi Hayakawa ,  Yasuhiro Jinbo ,  Kaname Mogami ,  Kenji Takeshita ,  Masanori Aritomi ,  Kunio Yoshikawa ,  Saburo Kikuchi ,  Akio Ishido

发明人： Shigeto Hayafuji ,  Takeshi Kamaya ,  Hiroshi Hayakawa ,  Yasuhiro Jinbo ,  Kaname Mogami ,  Kenji Takeshita ,  Masanori Aritomi ,  Kunio Yoshikawa ,  Saburo Kikuchi ,  Akio Ishido

IPC分类号： G21F9/30 ,  F16K5/06

CPC分类号： F16K5/06 ,  G21F9/28 ,  G21F9/30

摘要： Provided are a process and device for reducing radioactive material of an object containing the radioactive material to a safe level in a living environment.Included are a step of performing at least a step of carrying out a heating process on the object, into which radioactive material is absorbed and/or adsorbed from an environment or which absorbs and/or adsorbs radioactive material from an environment, in a state where temperature is less than or equal to the critical temperature of water and pressure is greater than or equal to the saturated vapor pressure of water, or a step of abruptly releasing the pressure; and a step of separating, after the above step, into liquid and solid.

摘要翻译： 提供了一种用于将包含放射性物质的物体的放射性物质还原到生活环境中的安全水平的方法和装置。 包括对在物体上进行放热物质的吸收和/或从环境中吸收和/或从环境中吸收和/或吸附放射性物质或从环境中吸收和/或吸附放射性物质的步骤的至少一个步骤， 温度小于或等于水的临界温度，压力大于或等于水的饱和蒸汽压，或突然释放压力的步骤; 以及在上述步骤之后分离成液体和固体的步骤。