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公开(公告)号：US09057703B2
公开(公告)日：2015-06-16
申请号：US14239892
申请日：2012-06-15
CPC分类号： G01N21/6486 , G01N15/0612 , G01N15/0656 , G01N21/643 , G01N35/04 , G01N2015/0046 , G01N2015/0065
摘要： A particle detection device detects a biological particle. The particle detection device includes a collection unit that collects a particle to a collection substrate, a fluorescence detection unit that emits excitation light toward the particle collected on the collection substrate and receives fluorescence emitted from the particle, and a cleaning unit that removes the particle from the collection substrate at a refreshing position separated from a collection/heating position and a detection position. At the collection/heating position, the particle is collected onto the collection substrate by the collection unit. At the detection position, fluorescence is received by the fluorescence detection unit. With such a structure, the particle detection device in which the particle is highly accurately detected is provided.
摘要翻译： 粒子检测装置检测生物粒子。 粒子检测装置包括将粒子收集到收集基板的收集单元，向收集基板收集的粒子发射激发光并接收从粒子发射的荧光的荧光检测单元，以及从粒子 所述收集基板位于与收集/加热位置分离的刷新位置和检测位置。 在收集/加热位置，通过收集单元将颗粒收集到收集基底上。 在检测位置，荧光检测单元接收荧光。 通过这样的结构，提供了高精度地检测出粒子的粒子检测装置。
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2.发明申请公开(公告)号：US20120136584A1
公开(公告)日：2012-05-31
申请号：US13388934
申请日：2010-07-26
申请人： Kazuo Ban , Kazushi Fujioka , Norie Matsui , Shuhji Nishiura , Hiroki Okuno , Katsutoshi Takao
发明人： Kazuo Ban , Kazushi Fujioka , Norie Matsui , Shuhji Nishiura , Hiroki Okuno , Katsutoshi Takao
CPC分类号： G01N15/1459 , G01N15/1429 , G01N2015/1486 , G01N2015/1493
摘要： A light receiving element provides a current signal corresponding to an amount of received light scattered by suspended particles moving at a predetermined speed to a pulse width measurement circuit and a current-voltage conversion circuit via a filter circuit. A pulse width measured from the current signal is converted into a voltage value based on a predetermined relationship by a pulse width-voltage conversion circuit, and is provided to a voltage comparison circuit. The current-voltage conversion circuit converts a peak value of the current signal into a voltage value, and an amplifier circuit amplifies the signal at a predetermined amplification factor and provides the same to the voltage comparison circuit. The voltage comparison circuit uses the voltage value converted from the pulse width as a boundary value, and the suspended particles causing the scattered light are detected as microorganisms when the peak voltage value is smaller than the boundary value.
摘要翻译： 光接收元件提供与通过以预定速度移动的悬浮颗粒散射的接收光的量相对应的脉冲宽度测量电路和电流 - 电压转换电路的电流信号。 从电流信号测得的脉冲宽度由脉冲宽度 - 电压转换电路基于预定的关系转换为电压值，并提供给电压比较电路。 电流 - 电压转换电路将电流信号的峰值转换为电压值，并且放大器电路以预定的放大系数放大信号并将其提供给电压比较电路。 电压比较电路使用从脉冲宽度转换的电压值作为边界值，当峰值电压值小于边界值时，引起散射光的悬浮颗粒被检测为微生物。
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公开(公告)号：US08901512B2
公开(公告)日：2014-12-02
申请号：US14239900
申请日：2012-06-15
申请人： Hideaki Fujita , Haruki Kamiyama , Kazushi Fujioka , Hiroki Okuno
发明人： Hideaki Fujita , Haruki Kamiyama , Kazushi Fujioka , Hiroki Okuno
CPC分类号： G01N21/6486 , G01N1/2202 , G01N15/0612 , G01N15/10 , G01N21/645 , G01N2001/2223 , G01N2015/0046 , G01N2015/0065 , G01N2021/6421 , G01N2021/6463 , G01N2201/062
摘要： There is provided a particle detector that can increase a detection sensitivity to fluorescence emitted from biogenic particles. A particle detector for detecting biogenic particles includes a substrate having a principal surface and configured to collect the biogenic particles on the principal surface, a light emitting element configured to irradiate particles collected on the principal surface with excitation light, and a light receiving element configured to receive fluorescence emitted from the particles when the particles are irradiated with the excitation light from the light emitting element. An optical axis of the Fresnel lens and a ray direction of the excitation light intersect with each other. The principal surface is a mirror surface.
摘要翻译： 提供了一种能够增加从生物颗粒发射的荧光的检测灵敏度的粒子检测器。 用于检测生物颗粒的颗粒检测器包括具有主表面并且被配置为在主表面上收集生物颗粒的基板，被配置为用激发光照射收集在主表面上的颗粒的发光元件，以及被配置为 当用来自发光元件的激发光照射颗粒时，接收从颗粒发射的荧光。 菲涅耳透镜的光轴和激发光的射线方向相交。 主表面是镜面。
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公开(公告)号：US20140175304A1
公开(公告)日：2014-06-26
申请号：US14239892
申请日：2012-06-15
IPC分类号： G01N21/64
CPC分类号： G01N21/6486 , G01N15/0612 , G01N15/0656 , G01N21/643 , G01N35/04 , G01N2015/0046 , G01N2015/0065
摘要： A particle detection device detects a biological particle. The particle detection device includes a collection unit that collects a particle to a collection substrate, a fluorescence detection unit that emits excitation light toward the particle collected on the collection substrate and receives fluorescence emitted from the particle, and a cleaning unit that removes the particle from the collection substrate at a refreshing position separated from a collection/heating position and a detection position. At the collection/heating position, the particle is collected onto the collection substrate by the collection unit. At the detection position, fluorescence is received by the fluorescence detection unit. With such a structure, the particle detection device in which the particle is highly accurately detected is provided.
摘要翻译： 粒子检测装置检测生物粒子。 粒子检测装置包括将粒子收集到收集基板的收集单元，向收集基板收集的粒子发射激发光并接收从粒子发射的荧光的荧光检测单元，以及从粒子 所述收集基板位于与收集/加热位置分离的刷新位置和检测位置。 在收集/加热位置，通过收集单元将颗粒收集到收集基底上。 在检测位置，荧光检测单元接收荧光。 通过这样的结构，提供了高精度地检测出粒子的粒子检测装置。
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5.发明申请公开(公告)号：US20120315666A1
公开(公告)日：2012-12-13
申请号：US13581224
申请日：2010-07-07
申请人： Kazushi Fujioka , Kazuo Ban , Norie Matsui , Hiroki Okuno
发明人： Kazushi Fujioka , Kazuo Ban , Norie Matsui , Hiroki Okuno
CPC分类号： G01N15/0612 , G01N1/44 , G01N15/0637 , G01N21/0332 , G01N21/6486 , G01N2015/0046 , G01N2015/0065 , G01N2015/0681
摘要： In a detection apparatus, an inlet and an outlet are opened and an air introducing mechanism is driven to introduce air to a case, and airborne particles are electrically attracted and held on a collecting jig 12. After introduction, the inlet and outlet are closed, and amount of fluorescence received by a light receiving element resulting from irradiation with light emitted from a light emitting element is measured by a measuring unit. Thereafter, the collecting jig is heated by a heater and the amount of fluorescence after heating is measured by the measuring unit. Based on the amount of change in the amount of fluorescence before and after heating, the amount of microorganisms collected by the collecting jig is calculated at the measuring unit.
摘要翻译： 在检测装置中，打开入口和出口，并且驱动空气引入机构以将空气引入到壳体中，并且将空气传播的颗粒电吸引并保持在收集夹具12上。在引入之后，入口和出口被关闭， 并且通过测量单元测量由从发光元件发射的光的照射而产生的受光元件所接收的荧光量。 此后，通过加热器加热收集夹具，并且通过测量单元测量加热后的荧光量。 基于加热前后的荧光量的变化量，在测定单元计算由收集夹具收集的微生物的量。
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公开(公告)号：US20050170211A1
公开(公告)日：2005-08-04
申请号：US11047216
申请日：2005-01-28
申请人： Kazushi Fujioka
发明人： Kazushi Fujioka
CPC分类号： H01L51/5052 , H01L51/0036 , H01L51/5012
摘要： An organic electroluminescent element comprising a hole injection electrode, an electron injection electrode and one kind or more of organic layers including a luminous layer between these electrodes, in which the organic layer includes a layer containing S, and metal or an oxide thereof is doped into the layer.
摘要翻译： 一种有机电致发光元件，其包括空穴注入电极，电子注入电极和在这些电极之间包含发光层的有机层中的一种或多种，其中有机层包括含有S的层，以及金属或其氧化物被掺杂到 层。
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公开(公告)号：US08941932B2
公开(公告)日：2015-01-27
申请号：US14239904
申请日：2012-06-15
申请人： Haruki Kamiyama , Hideaki Fujita , Kazushi Fujioka , Hiroki Okuno
发明人： Haruki Kamiyama , Hideaki Fujita , Kazushi Fujioka , Hiroki Okuno
IPC分类号： G02B3/08
CPC分类号： G02B3/08
摘要： A Fresnel lens includes an incident surface that is flat, and a prism-forming surface that has a plurality of prisms, the prism-forming surface being provided on the side of the Fresnel lens opposite to the incident surface. Each of the prisms has a converging surface that is located on the side away from the optical axis of the Fresnel lens.
摘要翻译： 菲涅尔透镜包括平坦的入射表面和具有多个棱镜的棱镜形成表面，棱镜形成表面设置在与入射表面相对的菲涅耳透镜侧。 每个棱镜具有会聚表面，其位于远离菲涅尔透镜的光轴的一侧。
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公开(公告)号：US20140218810A1
公开(公告)日：2014-08-07
申请号：US14239904
申请日：2012-06-15
申请人： Haruki Kamiyama , Hideaki Fujita , Kazushi Fujioka , Hiroki Okuno
发明人： Haruki Kamiyama , Hideaki Fujita , Kazushi Fujioka , Hiroki Okuno
IPC分类号： G02B3/08
CPC分类号： G02B3/08
摘要： A Fresnel lens includes an incident surface that is flat, and a prism-forming surface that has a plurality of prisms, the prism-forming surface being provided on the side of the Fresnel lens opposite to the incident surface. Each of the prisms has a converging surface that is located on the side away from the optical axis of the Fresnel lens.
摘要翻译： 菲涅尔透镜包括平坦的入射表面和具有多个棱镜的棱镜形成表面，棱镜形成表面设置在与入射表面相对的菲涅耳透镜侧。 每个棱镜具有会聚表面，其位于远离菲涅尔透镜的光轴的一侧。
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公开(公告)号：US20140166903A1
公开(公告)日：2014-06-19
申请号：US14239900
申请日：2012-06-15
申请人： Hideaki Fujita , Haruki Kamiyama , Kazushi Fujioka , Hiroki Okuno
发明人： Hideaki Fujita , Haruki Kamiyama , Kazushi Fujioka , Hiroki Okuno
IPC分类号： G01N21/64
CPC分类号： G01N21/6486 , G01N1/2202 , G01N15/0612 , G01N15/10 , G01N21/645 , G01N2001/2223 , G01N2015/0046 , G01N2015/0065 , G01N2021/6421 , G01N2021/6463 , G01N2201/062
摘要： There is provided a particle detector that can increase a detection sensitivity to fluorescence emitted from biogenic particles. A particle detector for detecting biogenic particles includes a substrate having a principal surface and configured to collect the biogenic particles on the principal surface, a light emitting element configured to irradiate particles collected on the principal surface with excitation light, and a light receiving element configured to receive fluorescence emitted from the particles when the particles are irradiated with the excitation light from the light emitting element. An optical axis of the Fresnel lens and a ray direction of the excitation light intersect with each other. The principal surface is a mirror surface.
摘要翻译： 提供了一种能够增加从生物颗粒发射的荧光的检测灵敏度的粒子检测器。 用于检测生物颗粒的颗粒检测器包括具有主表面并且被配置为在主表面上收集生物颗粒的基板，被配置为用激发光照射收集在主表面上的颗粒的发光元件，以及被配置为 当用来自发光元件的激发光照射颗粒时，接收从颗粒发射的荧光。 菲涅耳透镜的光轴和激发光的射线方向相交。 主表面是镜面。
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公开(公告)号：US06225239B1
公开(公告)日：2001-05-01
申请号：US09163975
申请日：1998-09-30
IPC分类号： H01L21469
CPC分类号： B05D1/185 , B82Y30/00 , B82Y40/00 , H01L21/3128
摘要： This invention provides a process for accumulating different organic molecular films on oxidized III-V-group compound semiconductor substrates in order to produce a stable, high-quality organic monomolecular film that is three-dimensionally regularly arranged, as well as a process for producing a fine pattern of such organic films. This organic film is formed by immersing a III-V group compound semiconductor substrates in a vessel containing a solution containing phosphonic acid dissolved into a solvent in order to form a self-assembled film, and placing the substrate into a different solution to adsorb metal ions to the surface of the film, or immersing the substrate in a bromide or an acid or alkali solution to denature functional groups, then immersing it in a solution containing organic molecules that are selectively chemically adsorbed to the modified functional groups. These steps are repeated to form a stable, high-quality multilayer film that is three-dimensionally regularly arranged, while controlling film thickness with an accuracy on the scale of thickness of a molecular layer. In addition, the present invention realizes the formation of a fine composite three-dimensional organic self-assembled film of the order of nanometer, characterized in that the process comprises using a cleavage method or a very-high-vacuum vessel to form on a substrate with different types of III-V-group semiconductor materials mixed thereon by means of the heteroepitaxial process such as the MBE or MOCVD process, a self-assembled film of the molecules having thiol groups in a non-oxidized area and then forming on an oxidized surface a self-assembled film of molecules having phosphoric acid group, trichlorosilyl groups or alkoxylyl groups.
摘要翻译： 本发明提供一种用于在氧化的III-V族化合物半导体衬底上积聚不同的有机分子膜的方法，以产生三维规则排列的稳定，高质量的有机单分子膜，以及制备 这种有机薄膜的精细图案。 该有机膜通过将III-V族化合物半导体基板浸渍在含有溶解于溶剂中的膦酸溶液的容器中形成自组装膜而形成，并将基板放置在不同的溶液中以吸附金属离子 或者将基材浸入溴化物或酸或碱溶液中以使官能团变性，然后将其浸入含有选择性地化学吸附至改性官能团的有机分子的溶液中。 重复这些步骤以形成三维规则排列的稳定，高质量的多层膜，同时以分子层厚度的精度控制膜厚。此外，本发明实现了 精细复合三维有机自组装膜的纳米级，其特征在于该方法包括使用切割方法或非常高的真空容器在具有不同类型的III-V族半导体材料的基底上形成 通过诸如MBE或MOCVD工艺的异质外延工艺在其上混合，在非氧化区域中具有硫醇基的分子的自组装膜然后在氧化表面上形成具有磷酸的分子的自组装膜 基团，三氯甲硅烷基或烷氧基。
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